ABSTRACT
Background: It was observed that post?COVID patients reported persistent exertional dyspnea, cough, fatigue, or chest pain. About 10%–20% of patients may progress to pulmonary fibrosis. Pulmonary rehabilitation has been proven to be useful in improving effort tolerance and quality of life in chronic respiratory diseases. Objectives: The objective of this study was to assess the effectiveness of pulmonary rehabilitation in improving 6?min walk distance (6 MWD), peak flow, fatigue, anxiety, and depression in early postacute COVID disease. Materials and Methods: This quasi?experimental study was conducted during January 2021 to March 2021. The patients who recovered from COVID?19 and having persistent exertional dyspnea and fatigue after 3 weeks of recovery were included in the study. Baseline and postintervention assessment of 6 MWD, Visual Analog Scale for Fatigue (VAS?F), peak flow, and Hamilton rating scales (HAM) scales after 4 weeks were done. Compliance was ensured with weakly telemonitoring. Results: Significant improvement in peak flow, 6 MWD, Hamilton Anxiety Rating Scale (HAM-A), Hamilton Depression Rating Scale (HAM-D), and VAS-F (P < 0.01) after 4 weeks of pulmonary rehabilitation. Conclusion: Early pulmonary rehabilitation in post?COVID syndrome can contribute to statistically significant improvement in functional and psychological parameters as well as post-COVID fatigue.
ABSTRACT
Introduction Normative comprehensive echocardiographic measurements data for healthy Indians are not available while data for American and European population is available from American Society of echocardiography and European Society of Cardiology/European Association of Cardio-Vascular Imaging and their publications. Available studies of Indian subjects are small and report only limited measurements with focus on left ventricular (LV) volumes. Objective We aim to provide comprehensive normative echocardiographic data for healthy Indians from a large sample size. Methods A retrospective cross-sectional single-center study of 707 healthy Indian adults age and sex segregated which presented detailed and comprehensive echocardiographic measurements including two-dimensional, M-mode, tissue Doppler imaging, speckle tracking echocardiography, chamber volumes, LV ejection fraction (LVEF), global longitudinal strain (GLS), segmental longitudinal strain and effort tolerance. Results Our findings show healthy Indians, as compared to US and European population, to have higher relative wall thickness. LV volumes, LV mass, LVEF and effort tolerance that were within American Society of Echocardiography described ranges for chamber quantification. Higher GLS values were observed in Indian population compared to European and American population. Women had higher LVEF and GLS values as compared to men and both showed a gradual decline with aging. Conclusion We present normal reference values for echocardiographic measurements in healthy Indian population, which could be used for future reference and comparison work.
ABSTRACT
La Enfermedad Pulmonar Obstructiva Crónica (EPOC) es una de las principales causas de morbimortalidad en todo el mundo. Representa un alto nivel de discapacidad afectando al individuo en todas sus áreas y determinando el deterioro funcional en sus actividades básicas cotidianas y en la relación con su entorno. El propósito fue determinar los cambios en el BODE-BODEX de pacientes con EPOC que culminaron un programa de Rehabilitación Pulmonar (RP) en la ciudad de Cali Colombia. Se realizó un estudio cuasiexperimental en 28 pacientes con diagnóstico de EPOC mayormente mujeres quienes ingresaron a un programa de RP entre enero de 2013 y julio de 2015. Se tuvo en cuenta la espirometría, el test de caminata de 6 minutos (6MWT), la valoración de la disnea y el índice de masa corporal. El grupo se clasificó principalmente en EPOC moderada. Con respecto a los valores pre y post RP, hubo cambios significativos en Disnea medida con la escala mMRC y la tolerancia al esfuerzo valorada con el 6MWT. No se encontraron variaciones respecto al IMC. La rehabilitación pulmonar generó cambios con significancia clínica y estadística en la tolerancia al esfuerzo reflejado en la distancia recorrida en el 6MWT, así como en la disnea según la mMRC y la fatiga de miembros inferiores, esta situación también generó cambios multidimensionales en la puntuación de los índices BODE-BODEX.
Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality worldwide. It represents a high level of disability affecting a person in all areas and determining the functional impairment in its basic daily activities and in relation to his surroundings. The purpose was to determine the changes in the BODE-BODEX of patients with COPD who accomplished a pulmonary rehabilitation program in Cali Colombia. A quasi-experimental study in 28 patients, most of them females, with a COPD diagnosis who were admitted to a PR program in the period January 2013 to July 2015. Spirometry, the 6 minute-walk test (6MWT), the assessment of dyspnea and body mass index were taken into account. They were classified mainly in moderate-COPD. With respect to the pre and post RP values, there were significant changes in dyspnea measured with the mMRC scale and effort tolerance assessed by the 6MWT. No variations were found related to BMI. Pulmonary rehabilitation generated changes of clinical and statistical significance in the effort tolerance reflected on the distance covered in the 6MWT as well as in dyspnea according to mMRC and fatigue of lower limbs. This situation also generated multidimensional score changes in BODE-BODEX index.