ABSTRACT
@#BACKGROUND. Annular elastolytic giant cell granuloma (AEGCG) is a rare skin disease, characterized by loss of elastic tissue due to elastophagocytosis by multinucleated giant cells in the upper part of dermis, which clinically presents as multiple annular plaques with raised erythematous border and central atrophy. We report a first case of AEGCG in dermatology practice in Mongolia. Its clinical and histological features, differential diagnosis and treatment modalities are described and discussed in detail.
ABSTRACT
Annular elastolytic giant cell granuloma is a rare form of granulomatous dermatosis, characterized clinically by annular plaques with slightly elevated margins, and histopathologically by the phagocytosis of elastic fibers by multinucleated giant cells. It typically occurs in sun-exposed areas of the skin in middle-aged women. However, some cases involving unexposed areas have been described. A 57-year-old man had erythematous plaques on both palms accompanied by a sensation of heat for 2 weeks. Histopathological examination revealed granulomatous infiltration with multinucleated giant cells and elastophagocytosis, which is consistent with annular elastolytic giant cell granuloma. Herein we report an interesting case of annular elastolytic giant cell granuloma that occurred on non-sun-exposed skin, palms.
Subject(s)
Female , Humans , Middle Aged , Elastic Tissue , Giant Cells , Granuloma, Giant Cell , Hot Temperature , Phagocytosis , Sensation , Skin , Skin DiseasesABSTRACT
Actinic granuloma is a rare chronic granulomatous dermatosis that is characterized by the elastophagocytosis by multinucleated giant cells. This malady presents in middle-aged individuals and it manifests as asymptomatic papules or annular plaques in the sun-exposed area. There are four main histopathologic patterns of actinic granuloma, including the giant cell, necrobiotic, histiocytic and sarcoidal variants. However, there are no previously reported cases of actinic granuloma associated with the histopathologic findings of suppurative granuloma. We herein report on an unusual case of actinic granuloma that showed the histopathologic findings of suppurative granuloma in a 58-year-old female.