ABSTRACT
OBJECTIVE@#To observe the effect on supplementary analgesia after total knee arthroplasty (TKA) treated with electroacupunture, and explore it's mechanism.@*METHODS@#A total of 40 patients with severe knee osteoarthritis were randomized into an observation group and a control group, 20 cases in each one. During the operation, patients were given epidural anesthesia in the two groups, conventional patient controlled epidural analgesia and oral celecoxib were applied after the operation. In the observation group, electroacupunture was used at Liangqiu (ST 34), Xuehai (SP 10), Yinlingquan (SP 9), Zusanli (ST 36), Fenglong (ST 40) and Qiuxu (GB 40) on the operation side from the 1st to 7th day after the operation to support analgesia, 30 min for each time, once a day. The visual analogue scale (VAS) was used to record postoperative pain of resting state and active state. The levels of serum prostaglandin E and β-endorphin were measured on the 1st and 7th day after surgery in the two groups.@*RESULTS@#In the observation group, the VAS scores of resting state and active state were superior to the control group on the 3rd, 5th and 7th day after the operaton (all <0.05); after the treatment, the level of serum β-endorphin was increased and the level of serum prostaglandin E was reduced in the two groups (all <0.05), and the change of the observation group was larger than that of the control group (both <0.05).@*CONCLUSION@#Electroacupunture has the effect of supplementary analgesia for patients after TKA, the mechanism may be related to promote the synthesis of β-endorphin and inhibit the synthesis of prostaglandin E.
Subject(s)
Humans , Analgesia, Patient-Controlled , Arthroplasty, Replacement, Knee , Pain Management , Pain, Postoperative , Prostaglandins , beta-EndorphinABSTRACT
El control postural es la capacidad de mantener el cuerpo en una posición sin oscilaciones o caídas, capacidad que es fundamental para el desarrollo de habilidades motoras y la funcionalidad Los enfermedades neurológicos han sido caracterizadas por limitaciones en el control postural, llevando o disfunciones del movimiento,funcionalidad y calidad de vida en la población adulto. la electroacupuntura (EA) es una terapia que podría contribuir a la mejoría del control postural, ligado a mecanismos de analgesia, que facilitarían la movilidad aumentos de circulación cerebral y liberación de factores neurotróficos en zonas asociados al control del movimiento. Sin embargo, es necesario entender con mayor profundidad estos mecanismos. Por esa razón, esta revisión busca identificar y comprender los efectos terapéuticos de la EA en el control postural en enfermedades neurológicos.
Postural control is the capacity to keep the body in a position without oscillation or falls, this ability is important for the development of mobility skilIs and functionality. Neurological diseases have been characterized by limitations in postural control, leading to dysfunction of movement, functionality and quality of ljfe. Electroacupunture (EA) is a therapy which could contribute to the improvement o postural control associated to analgesic mechanisms, that facilitate the mobility, increasing the cerebral circulation and release of neurotrophic factors in area associated with movement control However it is necessary to understand better about these mechanisms. For this reason, this review aimed to identify and comprehend the therapeutic effects of the EA on the control postural in neurological diseases.
Subject(s)
Humans , Electroacupuncture , Postural Balance , Nervous System Diseases/rehabilitationABSTRACT
Electroacupuncture (EA) has been widely used in pain relief. Clinical evidence has revealed its unique advantages and effectiveness in alleviating pain. Studies on EA and pain relief have revealed that EA displays greater analgesic effects for different types of pain in comparison to manual acupuncture. Here, we reviewed the clinical application and mechanism of EA in treating osteoarthritic knee pain and its influence factors in curative effect.
ABSTRACT
Objective To observe the effect of electroacupuncture (EA) intervention on the expression of Rho-associated kinase 1 (ROCK1) and Rho-associated kinase 2 (ROCK2) in rat peri-infarct cortex after middle cerebral artery occlusion (MCAO), so as to study the underlying mechanism by which EA improves cerebral ischemia. Methods Totally 40 male Sprague Dawley (SD) rats were equally randomized into four groups, control group, sham-operation group, model group and EA group. MACO in the model group and EA group was successfully established by an improved Longa procedure. EA was given 90 min after resuscitation for the EA group, once a day for 14 days. The modified neurological severity scores (mNSS) of rats in each group were determined on the 1st day, 3rd day, 7th day and the 14th day after operation. Immunohistochemistry and Western blotting analysis were used to detect the expression of ROCK1 and ROCK2 in the brain 14 d after operation. Results Neural dysfunction was not observed in the control group and sham-operation group. The values ofmNSS were significantly different between model group and EA group at 7 d, 14 d after operation (P<0. 05). Both immunohistochemical staining and Western blotting analysis indicated that the expression levels of ROCK1 and ROCK2 were up-regulated in model group, while those in EA group were significantly less than those in the model group (P<0. 05). Conclusion The expression of ROCK1 and ROCK2 is up-regulated in rat cortex after focal cerebral infarction, and the up-regulation can be prevented by EA intervention, which might be oneof the mechanisms by which EA promotes the recovery of neurological dysfunction after cerebral infarction.
ABSTRACT
[Objective]To contrast the influence of using the electro-needling machine on the Zusanli(ST36) or Shangjuxu(ST37) ,or on the two points both to treat the postoperative distension of the abdomen.And simultaneously to obverse whether using the two points together has the coordination effect or antagonistic effect.[Method] Adopting the stochastic grouping contrastive technique,dividing the 100 patients into the Zusanli group,the Shangjuxu group,the cooperative group and the blank group. To contrastively observe each situation,including the abdominal rumbles sound,the abdominal pain,the transformation of the incidental symptoms and the first time of exhaust,before and after the acupuncture treatment in each group.[Result]The treatment group has the therapeutic effect,with the blank group comparison,having the significant difference(P0.05)with each other.There's no obvious coordination effect or antagonistic effect during the treatment in the cooperative group. [Conclusion] Using the electro-acupunture on Zusanli,Shangjuxu can play an important part in improving the recuperation of the gastrointestinal function after surgical treatment. It also can obviously relieve uncomfortable postoperative symptoms.
ABSTRACT
To explore the mechanism of electroacupunture (EA) of Zusanli (ST36)in protecting gastric mucosa of dogs.Twenty mongrel dogs were randomly allocated to four groups: blank control group (Group A), non acupoint group (Group B), Shangjuxu (ST37) group (Group C) and Zusanli (ST36) group (Group D). Dynamic gastric mucosal blood flow (GMBF) was monitored by laser Doppler flowmeter and calcitonin gene related peptide (CGRP) contents in plasma and gastric mucosa were measured simultaneously by radioimmunoassay method. After sixty minutes of EA, GMBF and CGRP contents in plasma and gastric mucosa were increased in Group D (P
ABSTRACT
0.05) 1 day after acupuncture.There was a significant difference in the damage neurons of penumbrazone between the acupuncture and control groups(P