ABSTRACT
BACKGROUND: Since ciliary dysfunction of the respiratory system impair mucosal ciliary clearance, it is associated with recurrent or persistent upper respiratory infections, chronic bronchitis, chronic sinusitis, recurrent pneumonia, recurrent otitis media, bronchiectasis and chronic rhinitis. Primary ciliary dyskinesia has a familial tendency and it is known to have autosomal recessive trait, and rarely acquired trait. OBJECTIVES: We had this study in order to inspect whether primary ciliary dyskinesia is associated with recurrent or persistent upper respiratory problems or not. MATERIAL AND METHODS: From May 1995 through April 1996, by electron microscopy of the nasal mucosa, the authors analysed nine patients who had recurrent or persistent respiratory symptoms. RESULTS: Electron microscopic findings revealed primary ciliary dyskinesia in 4 patients with the symptoms of upper respiratory tract problems. CONCLUSION: It is concluded that nasal mucosal biopsy may be necessary for rule out primary ciliary dyskinesia in the patients with recurrent respiratory infections.
Subject(s)
Humans , Biopsy , Bronchiectasis , Bronchitis, Chronic , Kartagener Syndrome , Microscopy, Electron , Nasal Mucosa , Otitis Media , Pneumonia , Respiratory System , Respiratory Tract Infections , Rhinitis , SinusitisABSTRACT
The authors present a 3-year-old boy showing generalized migratory erythema with doubleedged scaling broders since 3 month after birth, Histologic examination revealed an acanthotic epidermis with hyperkeratosis, focal parakeratosis and papillomatosis. The PAS-positive, diastase-resistant amorphous materials were found in th space of parakeratoric scales and cytoplasms of spinous cells just below the parakeraroric lesion. On clectron microscopy, we could observe the round dense bodise in the upper spinous cells and a number of lipoid granules in the horny layer. Our patient showed characteristic clinical, clinical, microscopic and ultrastructural gearures of ichthyosis linearis citcumflexa(ILC). However, he showed no hair shaft abnormalities, which is the common finding of Metherthon/sysdrome(NS) along with ILC and atopic deathesis.
Subject(s)
Child, Preschool , Humans , Male , Cytoplasm , Epidermis , Erythema , Hair , Ichthyosis , Microscopy , Papilloma , Parakeratosis , Parturition , Weights and MeasuresABSTRACT
We report a case of an uncommon cutaneous neoplasm of nerve sheath myxoma in a 25-year-old woman who had a papule on the left cheek of her face. The histologic findings of the lesion showed that lobulated tumors were composed of spindle shaped and stellate tumor cells in an abundant matrix of mucosubstances. The electron microscopic findings showed numerous cytoplasmic myelin figures, and interdigitating long cytoplasmic processes. 5-100 protein was not discovered and alcian blue and PAS stain showed positive. After surgical excision of tumor, the patient did not have any evidence of disease for one year.
Subject(s)
Adult , Female , Humans , Alcian Blue , Cheek , Cytoplasm , Myelin Sheath , NeurothekeomaABSTRACT
Ultrastructural study was taken in a 48 year old male farmer with colloid milium. Electrcn microscopically, colloid was mainly composed of protofilaments, amorphous substance and degenerating collagens surrounded by halos. Colloidal filaments were curved and branched at their ends. Fibroblasts near the colloid island contained amorphous materials and protofilaments idnitical to that of colloid materials, Thus we suggest that. colloid milium may be produced by the abnormal fibroblasts or may be derived from actiinically damaged collagen fibers.