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Objective@#To investigate the clinical application of injected autologous fat and buried polydioxanone threads for nasolabial fold filling.@*Methods@#From April 2016 to October 2017, 64 cases of mild and moderate nasolabial fold beauty seekers from the First People＇s Hospital of Jiande were divided into group A and group B with their attitude. Group A (28 cases) were only treated with buried polydioxanone threads for nasolabial fold filling; Group B (36 cases) were treated with injected autologous fat and buried polydioxanone threads for nasolabial fold filling. The surgical effect was recorded for 18 months.@*Results@#The most common complications were swelling, bruising and pain immediately after the surgery. Polydioxanone threads exposure occurred in two cases in each group 2 weeks after the surgery. There were satisfactory results in skin color and skin texture in both groups. 9 cases showed inadequate correction in group A while only 2 cases showed inadequate correction in group B in long-term follow-up (>3 months).@*Conclusions@#Combined treatment of autologous fat and polydioxanone threads is safe and effective for nasolabial fold filling.
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Objective To observe the clinical efficacy of acupoint thread-embedding in treating premature ovarian failure.Method By following the visiting or admission sequence, 35 patients were randomized into a treatment group (acupoint thread-embedding group) and a control group (Western medication group). The therapeutic efficacy, and the levels of follicle stimulation hormone (FSH), luteinizing hormone (LH) and estradiol (E2) before and after the treatment were observed.Result After the treatment, the recovery rate and total effective rate were respectively 44.4% and 72.2% in the treatment group, significantly different from 0.0% and 52.9% in the control group (P0.05).Conclusion Acupoint thread-embedding can produce a satisfactory efficacy in treating premature ovarian failure.
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Objective To observe the clinical efficacy of acupoint thread embedding on the peripheral serum leptin and insulin levels in simple obesity patients, and to further explore the mechanism of acupoint thread embedding in treating simple obesity.Method A total of 120 patients with simple obesity were randomized into a control group, an eletroacupuncture (EA) group and a thread embedding group, 40 cases in each group. The control group was intervened by diet plus exercise intervention, the EA group by EA treatment in addition to the intervention given to the control group and the thread embedding group by acupoint thread embedding treatment in addition to the intervention given to the control group. The levels of blood serum leptin and insulin in the three groups were observed before and after 2 treatment courses and the clinical efficacies were compared among the three groups.Result The total effective rate was 87.5% in the thread embedding group, 85.0% in the EA group, and 47.5% in the control group. The total effective rates in the thread embedding group and EA group were significantly different from the rate in the control group (P<0.05). The levels of the fasting serum leptin and insulin were significantly changed in the thread embedding group and EA group after the treatment (P<0.01). After the treatment, the levels of the fasting serum leptin and insulin in the thread embedding group and EA group were significantly different from those in the control group (P<0.01,P<0.05). The insulin level in the thread embedding group was better than that in the EA group, and the difference was statistically significant (P<0.05).Conclusion Acupoint thread embedding is an effective approach for simple obesity, and it can down-regulate the fasting peripheral serum leptin and insulin levels.
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Objective To analyze the bibliometry of the literature of acupoint thread-embedding in treating simple obesity, and to provide references for clinic.Method By both computer and manual retrieval, the relevant literatures over the past 30 years were collected from the Chinese Journal Full-text Database (CJFD), Vip database, WanFang database. By using the SPSS 17.0 software for statistical analysis, the distribution (province or city), publication year, and journal of the literatures, supporting fund, sample size, research method, material of the thread, use frequency of the involved acupoints, and the meridians of the selected acupoints were summarized.Result The included eligible 175 articles were distributed over many provinces and cities; the publication amount had been increasing year by year; there was a variety of thread materials; the literature with supporting funds only occupied a small percentage, while the research with a small sample size occupied a comparatively large percentage, and the randomized controlled trials (RCTs) also had a small percentage.Conclusion As a common Chinese external therapy in treating simple obesity, acupoint thread-embedding has been paid more and more attention for its practical value and bright future. However, the relevant governmental department hasn’t paid enough attention to this therapy, and the low clinical research quality also makes it difficult to scientifically evaluate its clinical efficacy and safety. Therefore, more attention is required, RCTs of multicenter and large sample size are expected, and clinical research quality also needs improvement, to provide references for clinic.
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ObjectiveTo observe the clinical efficacy of microinvasive thread embedding plusShe Gan Ma Huangdecoction based on ordinary Western medications in treating chronic obstructive pulmonary disease (COPD) (cold-phlegm obstructing the lung). MethodThe treatment group was intervened by microinvasive thread embedding plusShe Gan Ma Huangdecoction based on ordinary Western medications, while the control group was by the Western medications alone.ResultThe markedly effective rate and total effective rate were respectively 10.0% and 93.3% in the treatment group;the pulmonary function showed significant improvements in both groups.ConclusionMicroinvasive thread embedding plusShe Gan Ma Huangdecoction based on Western medications can produce a more significant therapeutic efficacy than dry Western medicationsin treating COPD (cold-phlegm obstructing the lung) in acute attack stage, and it can simultaneously improve the pulmonary function.
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ObjectiveTo compare the therapeutic efficacies between acupoint thread embedding plus Western medication and dry Western medication in treating metabolic syndrome.MethodTotally 320 patients with metabolic syndrome were randomized into a treatment group and a control group, 160 cases in each group. The control group was intervened by ordinary Western medication, while the treatment group was by acupoint thread embedding in addition to the Western medication given to the control group, and Yishu (Extra), Geshu (BL17), Ganshu (BL18), Pishu (BL20), Shenshu (BL23), Tianshu (ST25), Daimai (GB26), and Guanyuan (CV4) were selected as the major points. The therapeutic efficacies, metabolism-related parameters, liver function, and kidney function were compared between the two groups, and the therapeutic efficacies of different syndromes were also compared.ResultThe markedly effective rate and total effectiverate of the treatment group were significantly higher than that of the control group (P0.05), but there were significant inter-group differences in comparing the rest parameters including liver and kidney functions (P<0.05), and the treatment group was superior to the control group. Acupoint thread embedding produced a more significant efficacy in treating metabolic syndrome due to heat in liver-stomach and phlegm-dampness stagnancy compared to the control group (P<0.05), and the efficacy of acupoint thread embedding in treating metabolic syndrome due to phlegm-dampness stagnancy was significantly different from that of the control group (P<0.01).ConclusionAcupoint thread embedding plus Western medication can produce a more significant therapeutic efficacy in treating metabolic syndrome compared to Western medication alone, and it’s safe; of all the patterns, phlegm-dampness stagnancy responds thebest to acupoint thread embedding.
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Objective To observe the clinical efficacy of thread embedding at Back-Shu points in treating stroke-associated pneumonia.Method Seventy patients with stroke-associated pneumonia were randomized into a treatment group and a control group, 35 cases in each group. The control group was intervened by regular medications, while the treatment group was additionally intervened by thread embedding at the Back-Shu points. Before and after the intervention, C-reactive protein (CRP), white blood cell (WBC), neutrophil ratio (NE%), and symptoms and signs scores were observed, and the clinical efficacies were compared between the two groups.Result The CRP, WBC, NE%, and symptoms and signs scores were significantly changed after intervention in both groups (P<0.05). After intervention, the CRP, WBC, NE%, and symptoms and signs scores in the treatment group were significantly different from that in the control group (P<0.05). The total effective rate was 91.4% in the treatment group, versus 82.9% in the control group, and the difference was statistically significant (P<0.05).Conclusion Thread embedding at the Back-Shu points can promote the treatment of stroke-associated pneumonia.
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Objective To observe the clinical efficacy of thread embedding at the holographic point Kidney of the second metacarpal bone in treating tinnitus.Method Eighty-two patients with tinnitus were randomized into a treatment group and a control group, 41 cases in each group. The treatment group was intervened by thread embedding at the holographic point Kidney of the second metacarpal bone, while the control group was by intragluteal injection with Mecobalamin 0.5 mg. The Tinnitus Handicap Inventory (THI) was compared before intervention and after 1 treatment course.Result The THI scores were significantly changed in both groups after intervention (P<0.01). The change of THI score after intervention in the treatment group was significantly different from that in the control group (P<0.05).Conclusion Thread embedding at the holographic point of the second metacarpal bone in an effective approach in treating tinnitus.
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Objective To investigate the therapeutic effect of microinvasive PGLA thread embedding on neck pain due to cervical spondylosis. Method One hundred and five cervical spondylosis patients with complaints of neck pain were randomly allocated to three groups, 35 cases each. The thread embedding group received PGLA thread embedding therapy;the control group, acupuncture with thread-embedding needles (without thread embedding);the acupuncture group, conventional acupuncture. Result There was a significant difference in the relief of symptoms and signs between the thread embedding or acupuncture group and the control group (P<0.05). There were statistically significant pre-/post-treatment differences in the VAS score and the PPI score in the thread embedding and acupuncture groups (P<0.05). There were statistically significant post-treatment differences in the above scores between the thread embedding or acupuncture group and the control group (P<0.05). The total efficacy rate was 17.1% in the control group, 77.1%in the acupuncture group and 94.3%in the thread embedding group. The total efficacy rate was significantly higher in the thread embedding group than in acupuncture and control groups. Conclusion The therapeutic effect on neck pain due to cervical spondylosis is produced by PGLA thread stimulation of the acupoints and not by simple injurious stimulation with thread-embedding needles. PGLA thread embedding has a marked therapeutic effect on neck pain due to cervical spondylosis.
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Objective To observe the clinical efficacy of yang-supplementing thread-embedding (acupoint embedded with catgut soaked in Shenfu injection) in treating shoulder-hand syndrome after cerebral stroke. Method Totally 120 patients were randomized into a treatment group and a control group, 60 cases in each group. The treatment group was intervened by acupoint thread-embedding, while the control group was by conventional acupuncture. The changes of symptoms, joint range of motion (ROM), pain, and Fugl-Meyer Assessment (FMA), and general therapeutic efficacy were observed after 30 d treatment. Result The total effective rate was 95.0% in the treatment group versus 85.0% in the control group, and the difference was statistically significant (P<0.05). Conclusion Yang-supplementing thread-embedding and conventional acupuncture both can mitigate pain induced by shoulder-hand syndrome, increase the range of motion, and significantly improve the upper-limb motor function, while the effect of yang-supplementing thread-embedding is superior to that of conventional acupuncture.
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Objective To observe the clinical efficacy of Li Jiao Tong Fu (regulating the triple energizers and unblocking the Fu-organs) acupoint thread-embedding in treating functional constipation. Method Sixty eligible subjects were randomized into a treatment group and a control group, 30 cases in each group. The treatment group was intervened by acupoint thread-embedding at Tianshu (ST25), Shuidao (ST28), Zusanli (ST36), Shangjuxu (ST37), and Danchangshu (BL25), once every 2 weeks, totally for 2 sessions. The control group was by sham thread-embedding at the same points with the same treatment duration. The Patient Assessment of Constipation-Symptom (PAC-SYM), Patient Assessment of Constipation-Quality of Life (PAC-QOL), Self-rating Anxiety Scale (SAS), and two factors from PAC-SYM, hard bower movement and bloating, were observed before and after the intervention, and the clinical efficacies were compared. Result The total effective rate was 83.3% in the treatment group versus 46.7%in the control group, and the total effective rate of the treatment group was significantly higher than that of the control group (P<0.05). The PAC-SYM, PAC-QOL, and bloating scores were significantly improved after the intervention in the two groups (P<0.05), and the improvements in the treatment group were more significant than that in the control group (P<0.05). The score of hard bower movement was markedly improved after the intervention in the treatment group (P<0.05), and the score in the treatment group was significantly lower than that in the control group (P<0.05). Conclusion Li Jiao Tong Fu acupoint thread-embedding is significantly effective in treating functional constipation, and it’s easy-to-operate, safe and reliable, and has a good compliance, thus worth promoting in clinic.
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ObjectiveTo observe the clinical efficacy of acupoint thread-embedding in treating perimenopausal insomnia in women.MethodSixty outpatients with perimenopausal insomnia were randomized into a thread-embedding group and an acupuncture group, 30 in each group. The thread-embedding group was intervened by acupoint thread-embedding by selecting Xinshu (BL15), Ganshu (BL18), Pishu (BL20), Shenshu (BL23), Qihai (CV6), Guanyuan (CV4), Neiguan (PC6), Zusanli (ST36), and Sanyinjiao (SP6), once a week, successive 3 sessions as a treatment course; the acupuncture group was intervened by regular acupuncture by selecting the same acupoints following the same treatment course, 3sessions a week. The Pittsburgh Sleep Quality Index (PSQI) was adopted for evaluation, and a 30-d follow-up was conducted for observing the efficacy.ResultThere was no significant difference in comparing the total effective rate between the two groups (P>0.05). After intervention, the PSQI scores were significantly changed in both groups (P<0.01). In the follow-up, the PSQI global score, sleep quality, sleeping pills, and daytime function scores in the thread-embedding group were significantly differentfrom that in the acupuncture group (P<0.01). ConclusionThread-embedding can produce a more significant efficacy than using acupuncture in treating perimenopausal insomnia in women.
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ObjectiveTo evaluate the clinical efficacy of micro-invasive thread-embedding in treating allergic rhinitis.Method Sixty eligible patients were randomized into a control group and a thread-embedding group. Thecontrol group was intervened by Budesonide nasal spray, while the thread-embedding group was by micro-invasive thread-embedding in addition to the nasal spray. The therapeutic efficacy was evaluated after 2-month treatment.ResultThe symptom score and symptom-sign global score were decreased significantly in both groups after intervention (P<0.05), the improvement of stuffy nose and running nose and the global score of the thread-embedding group were significantly superior to that of the control group (P<0.05); the quality of life scores were markedly improved in both groups after intervention (P<0.05), and the improvement of non-nasal/eye symptoms, actual symptoms, and nasal symptoms, as well as the global score in the thread-embedding group were superior to that in the control group (P<0.05); the total effective rate was 96.7% in the thread-embedding group, significantly higher than 66.7% in the control group (P<0.01).ConclusionMicro-invasive thread-embedding can produce a content efficacy in treating allergic rhinitis, and can enhance the quality of life.
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Objective To observe the clinical efficacy of micro-invasive point-through-point thread-embedding in treating acute stage of post-stroke shoulder-hand syndrome. Method Sixty patients were randomized into a treatment group and a control group, 30 in each group. Patients in the treatment group were intervened by micro-invasive point-through-point thread-embedding in addition to rehabilitation training, while patients in the control group were by rehabilitation training alone. Before treatment and after 4-week treatments, Visual Analogue Scale (VAS) was used to estimate shoulder pain, modified Barthel Index (MBI) to detect the activities of daily life, and Fugl-Meyer Assessment Scale to measure the motor function of upper limb. Result Before treatment, there were no significant differences in comparing the involved indexes between the two groups (P>0.05), and the indexes were significantly improved after intervention in both groups (P<0.05). Conclusion Micro-invasive point-through-point thread-embedding can reduce pain intensity, improve the activities of daily life and motor function of upper limb of patients in acute stage of post-stroke shoulder-hand syndrome.
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ObjectiveTo observe the therapeutic efficacy ofacupoint thread embedding in treating hyperlipidemia, and to explore a treatment method with valid efficacy and few side effects.MethodSixty patients with hyperlipidemia were randomized into a thread embedding group and a medication group, 30 cases ineach group. The thread embedding group was intervened by thread embedding at Zhongwan (CV12), Tianshu (ST25), Fenglong (ST40), and Zusanli (ST36), once a week; the medication group was by taking Xue Zhi Kang capsules, two capsules each time, twice a day. The two groups both received treatment for 8 weeks. The clinical efficacy, total cholesterol (Chol), and triglyceride levels were observed before and after treatment.ResultThe total effective rate was 86.7% in the thread embedding group versus 83.3% in the medication group, and the difference was statistically insignificant (P>0.05). After 4-week treatment, the transaminase level increased in 3.3% of the patients in the medication group, while no one showed an increased transaminase level in the thread embedding group. After 8-week treatment, the observed indexes were increased in the medication group, while those in the thread embedding group were still stable.ConclusionAcupoint thread embedding is effective in treating hyperlipidemia, and the effect is durable with few side effects.
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Objective To observe the clinical efficacy of thread-embedding at scalp points in treating insomnia.Method Sixty-four insomnia patients were randomized into a treatment group of 33 cases and a control group of 31 cases. The treatment group was intervened by thread-embedding at scalp points, while the control group was by orally taking Estazolam. Four weeks were taken as a treatment course, and the clinical efficacies and changes of indexes were measured after a treatment course.Result The total effective rate was 90.0% in the treatment group versus 90.3% in the control group, and the difference was statistically insignificant (P>0.05). The item scores of Pittsburgh Sleep Quality Index (PSQI) were changed significantly after treatment in both groups (P<0.01). The changes of sleep latency and daily function disturbance in the treatment group were significantly different from that in the control group (P<0.05).Conclusion Thread-embedding at scalp points and oral administration of Estazolam both can improve insomnia symptoms. Thread-embedding at scalp points is inferior to Estazolam in improving sleep latency but is superior to Estazolam in improving daily function.
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Objective To observe the efficacy of Zhuang’s medicated thread moxibustion plus acupoint thread embedding in treating allergic rhinitis.Method By using random number table, 103 patients with allergic rhinitis were randomized into a treatment group (n=53) and a control group (n=50). The treatment group was intervened by Zhuang’s medicated thread moxibustion and acupoint thread embedding, while the control group was by acupoint thread embedding alone. The subjects were treated for 6 courses with a one-month follow-up. The therapeutic efficacies were compared between the two groups.Result The total effective rates were respectively 94.3% and 80.0% in the treatment group and control group.Conclusion Zhuang’s medicated thread moxibustion plus acupoint thread embedding has significant advantage in improving the symptoms of allergic rhinitis.
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Objective To observe the clinical efficacy of acupoint thread embedding in treating simple obesity and its effect on blood lipids and insulin.Method Eighty patients were randomized into a thread embedding group and an acupuncture group. The acupoint thread embedding was given once every week, while acupuncture was given six times a week, both for 8 weeks in total. The body weight, body mass index (BMI), chest circumference, waist circumference, hip circumference, insulin and blood lipids were observed before and after intervention.Result After intervention, body weight, BMI, waist circumference, waist-hip ratio, fasting insulin level, blood lipids, and insulin resistance dropped significantly in both groups (P0.05).Conclusion Acupoint thread embedding can reduce body weight and three circumferences, and modulate glucose and lipid metabolisms, through which approaching weight loss in a healthy way.
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ObjectiveTo observe the efficacy of thread embedding at tender points on the Governor Vessel in treating intractable insomnia.MethodEighty eligible subjects were randomized into two groups. The thread embedding group was intervened by thread embedding at tender points on the Governor Vessel, while the acupuncture was by ordinary acupuncture.ResultThe recovery and markedly effective rate in the thread embedding group (72.5%) was markedly higher than that in the acupuncture group (45.0%). The Pittsburgh Sleep Quality Index (PSQI) scores were significantly lower after intervention in both groups (P<0.05); the PSQI score in the thread embedding group was significantly lower than that in the acupuncture group after intervention (P<0.05). ConclusionThread embedding at tender points on the Governor Vessel can produce a more significant efficacy than ordinary acupuncture in treating intractable insomnia, and it can more effectively improve sleep quality.
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ObjectiveTo compare the therapeutic efficacies and adverse reactions of micro-invasive thread embedding with two types of materials in treating chronic facial paralysis.MethodTotally 186 patients with chronic facial paralysis were randomized into a catgut group and a PDS group, 93 cases in each group. For the two groups, Cuanzhu (BL2), Yuyao (EX-HN4), Taiyang (EX-HN5), Dicang (ST4), Jiache (ST6), Quanliao (SI18), Yingxiang (LI20), Qianzheng (Extra), Xiaguan (ST7), Fengchi(GB20), and bilateral Hegu (LI4) and Zusanli (ST36) were selected. The thread embedding treatment was given once every 10 d, 3 timesas a treatment course, successively for 2 courses. The therapeutic efficacy and adverse reactions were analyzed after 2 treatment courses. ResultThe Sunnybrook Facial Grading System scores were significantly increased after intervention in the two groups (P0.05). There were no significant differences in comparing the adverse reactions including tenderness, nodules, and swelling right after thread embedding between the two types of materials (P>0.05); 10 d after thread embedding, the adverse reactions happened inthe catgut group were significantly more than that in the PDS group (P0.05).Conclusion Acupoint thread embedding with PDS can help recover facial nerve function in chronic facial paralysis; as a thread embedding material, PDS thread produces a lower occurrence rate of adverse reactions, and thus it’s a kind excellent thread embedding material.