ABSTRACT
Objective To characterize the clinical features and assess the role of surgery in posterior cortex epilepsy. Methods A retrospective analysis of clinical data was performed in 43 patients with posterior cortex epilepsy. The diagnosis Was established by means of a standard presurgical evaluation, including ictal semiology, MRI, interictal and ictal scalp video-EEG, and additional intracranial EEG monitoring in selected cases. Results The 43 patients included 11 parietal lobe epilepsy, 13 occipital lobe epilepsy, and 19 patients with seizures originating from other part of posterior cortex. Thirty-three patients (76.7%)experienced at least one type of aura, such as visual aura, somatosensory aura, dizziness and so on. The common ictal manifestations included deviation, automatisms, tonic posture and so on. Intracranial EEG monitoring was preformed in 22 selected cases. Transient contralateral hemiparesis occurred in 2 patients, mixed aphasia in 1 patient, and they recovered in 3 weeks after surgery. Visual and visual field deficits were observed in 5 patients, and they did not fully recovered. All patients were followed-up 1 to 5 years, and 27(62.8%)became seizure free (Engel' S I class). Conclusions Some of the specific auras or ictal manifestations may indicate posterior cortex epilepsy. Favorable surgical outcome has been achieved in many of the patients.
ABSTRACT
Objective To study the efficacy and safety of flunarizine (FNR) used as an open add on therapy with increasing dosage for treatment of intractable partial seizures (IPS) Methods Fourty three patients with IPS received FNR add on therapy more than 6 months in addition to the medication of existing antiepileptic drug The administration of FNR in increasing dosage was executed as follows: for children aged 8 12 years,the initial dosage was 5 mg/d in the first week,then with a subsquent increase of 5 mg/d every week; for adult,10 mg/d for the first week,and then increased 10 mg/d each week And at the fourth week,the dosage of FNR for children was added up to 20 mg/d,and for the adult, 40 mg/d served as a maintenance dosage continuously for 6 months Results Two patients dropped out for personal reasons Three cases discontinued FNR add on therapy because of untolerable adverse effects of increasing dosage Thiry eight patients accomplished the whole course of 6 month treatment Total effective rate was 63%,in which there was 75% for simple partial seizures (SPS), 62% for complex partial seizures(CPS) and 56% for the secondary general seizures(SGS) There was a seizure reduction of 69% as compared with pre FNR treatment period ( P
ABSTRACT
Se estudiaron 30 niños que padecen crisis epilépticas parciales y que asisten a escuelas primarias normales, con el objetivo de conocer si presentan dificultades escolares y en qué asignaturas, para esto se realizó una evaluación psicopedagógica. Los resultados se compara-ron con un grupo control de 30 niños para lo cual se utilizó el test de comparación de medias. Se halló que 18 niños del grupo estudio (60 %) y 9 del grupo control (30 %) presentaron alguna dificultad en el cumplimiento de los objetivos del grado escolar, con una diferencia significativa entre los grupos de p < 0,001. Se concluye que las mayores dificultades escolares se encuentran en las áreas de Lectura y Español.
Thirty children with partial epileptic crisis that go to normal primary schools were studied, with the objective of knowing if they have learning difficulties, and in which subjects; with this purpose, a psychopedagogical assessment was carried out. Results were compared with a 30 children control group, and this was made through the mean comparison test. It was found that 18 children from the study group (60 %), and 9 from the control group (30 %) presented some difficulties in achieving the goals of the school grade with a significant difference between groups of p < 0,001. It is concluded that the highest learning difficulties are in the areas of Reading and Spanish.