ABSTRACT
Objective To explore the level change of peripheral blood lymphocyte subgroup ,the erythrocyte zinc and hs-CRP in children with hand-foot-mouth disease (HFMD) .Methods Children with severe HFMD in this hospital were selected as experi-mental group ,and children in health that received physical examination in this hospital were selected as control group .Level of the peripheral blood lymphocyte subsets ,erythrocyte zine and hs-CRP were detected .Results In the HFMD group ,total T cell percent-age(CD3 + ) ,auxiliary/ induced T cells (CD3 + CD4 + ) percentage ,inhibit/cytotoxic T cells(CD3 + CD8 + ) percentage ,and the eryth-rocyte zine levels were all significantly lower than that of the control group(P< 0 .05) ,while the hs-CRP determination level ,B cells (CD19 + ) percentage were significantly higher than those of the control group(P< 0 .05) .Conclusion Children with severe HFMD have cellular immunity and hormone immunity function disorder and are lack of erythrocyte zinc .And their body cannot effectively resist infection virus ,which can lead to secondary bacterial infection .
ABSTRACT
Introduction: According to the National Nutrition and Health Survey of Argentina, 33 ,5 percent of women aged 14 to 49 years old could have alow zinc intake. Nevertheless, there is no information about the biochemical evaluation of zinc nutritional status in women at a reproductive age. Objective: To carry out an exploratory survey in order to study three biochemical parameters: zinc in plasma (ZnP), zinc in erythrocyte (ZnE) and the relationship zinc I Hemoglobin (Hb) in a group of female university students. Methods: The sample included 48 university students without pathologies who accepted to participate in the survey. Participants were evaluated by anthropometric measurements and Body Mass Index (BMI) was calculated. Fasting blood samples were obtained and plasma Zn and erythrocyte Zn levels were determined by atomic absorption spectrometry. Results: The group had a mean +/- standard deviation of 22,3 +/- 3,3 years and the anthropometric characteristics were: weight (kg)...
Introducción: en Argentina es muy escasa la información bioquímica respecto al estado nutritional con respecto al zinc (Zn) en mujeres en edad fértil. Según la Encuesta Nacional de Nutrición y Salud el 33,5 por ciento de las mujeres de 10 a 49 años presentan una ingesta inadecuada. Objetivos: La finalidad de este trabajo exploratorio fue estudiar el comportamiento de tres indicadores bioquímicos: Zn en plasma (ZnP), Zn en eritrocito (ZnE) y la relación Zn/Hb en un grupo de estudiantes universitarias. Métodos: La muestra estuvo constituida por 48 estudiantes universitarias clínicamente sanas, que aceptaron ser incluidas en el estudio. Se les realizó una evaluación antropométrica mediante la determinación del IMC. Se les extrajo sangre venosa en ayunas, determinando ZnP y ZnE por espectofotometría de absorción atómica. Resultados: El grupo estudiado presentó una edad promedio de 22.3 +/- 3.3 años y las siguientes características antropométricas (Media +/- DE): peso (kg): 56.0 +/- 6.8; talla (m): 1.62 +/- 0,05; IMC (kg/m2):21.3 +/- 2.2. Las estadísticas descriptivas: media +/- DE, (IC 95 por ciento) y...
Subject(s)
Humans , Adult , Female , Erythrocytes , Hemoglobins/analysis , Students , Zinc/blood , Argentina , Body Mass Index , Cross-Sectional Studies , Biomarkers/blood , Nutritional Status , Reference Values , Spectrophotometry, AtomicABSTRACT
Se estudiaron adultos, clínicamente sanos, 21 varones (V) y 19 mujeres (M), de: edad (años): V: 48±14 (28-78); M: 41±14 (23-66); Índice de masa corporal (kg/m²): V: 26,7±2,3 (23,1-31,9); M: 22,2±3,5 (19,3-29,6). Se realizó una encuesta nutricional y se extrajo sangre en ayunas. Se realizaron las determinaciones de rutina del laboratorio clínico. Se determinó zinc en plasma (ZnPl), cobre en suero (CuS); en eritrocitos: Zinc (ZnGR) y cobre (CuGR), por espectrometría de absorción atómica. La totalidad de los V y M presentaron ingestas adecuadas de energía, proteínas, Zn y Cu. Los resultados expresados como: promedio ± desvío estándar y rangos fueron: ZnPl (μg/dL): V: 93±27 (49-161); M: 79±28 (42-157); ZnGR (μg/dL): V: 1.380±210 (1.110-2.010); M: 1.350±130 (1.090-1.520); CuS (μg/dL): V: 89±20 (40- 122); M: 93±28 (45-157). CuGR (μg/dL): V: 59±12 (37-78); M: 63±19 (30- 110). No se evidenciaron diferencias significativas entre V y M. Los resultados para la población estudiada fueron, percentilos 5 y 95, respectivamente: ZnPl: 49 a 131 μg/dL; ZnGR: 1.130 a 1.610 μg/dL; Zn/Hb: 34,4 a 47,5 μg/g; CuS: 45 a 124 μg/dL; CuGR: 36 a 78 μg/dL. Los valores de ZnPl y CuS se encuadraron dentro de los rangos de valores de referencia internacionales, sin diferencias significativas de acuerdo con el género.
Two groups of adult healthy people were studied: 21 males (M) and 19 females (F). Mean age (ys) was: M: 48±14 (28-78); F: 41±14 (23-66); body mass index (Kg/m²) was: M: 26.7±2.3 (23.1-31.9); F: 22.2±3.5 (19.3-29.6). A nutritional survey was recorded and mean daily intake of energy, protein, Zinc (Zn) and Copper (Cu) were calculated. Fasting blood samples were obtained in order to determine Hemoglobin (Hb), plasmatic Zn (PlZn), serum Cu (SCu), erythrocyte Zn (EZn) and erythrocyte Cu (ECu) levels. Zn and Cu were determined by AAS. Results were: mean±SD and ranges: PlZn (μg/dL): M: 93±27 (49-161); F: 79±28 (42-157); EZn (μg/dL): M: 1380±210 (1110-2010); F: 1350±130 (1090-1520); SCu (μg/dL): M: 89±20 (40-122); F: 93±28 (45-157). ECu (μg/dL): M: 59±12 (37-78); F: 63±19 (30-110). All individuals presented adequate intake of energy, protein, Zn and Cu. There were no significant differences between M and F for PlZn, EZn, Zn/Hb ratio, SCu and ECu. The results for the adult healthy population in Argentina, and which were in accordance with the international published values were: (percentiles 5 y 95, respectively): PlZn: 49 - 131 μg/dL; EZn: 1130 - 1610 μg/dL; Zn/Hb: 34,4 - 47,5 μg/g; SCu: 45 - 124 μg/dL; ECu: 36 - 78 μg/dL.