ABSTRACT
Objective: To study the chemical constituents of the stems and leaves of mangrove plant, Scyphiphora hydrophyllacea. Methods: The chemical constituents of S. hydrophyllacea were separated and purified by silica gel, ODS, Sephadex LH-20 gel column chromatographies and preparative HPLC. Their structures were identified by physicochemical properties, spectroscopic analysis, as well as comparisons with the data reported in literatures. Results: A total of 18 compounds were isolated from the 90% ethanol extract of the stems and leaves of S. hydrophyllacea, which were identified as pomonic acid (1), euscaphic acid (2), dammaradienyl acetate (3), erythrodiol (4), lupenyl acetate (5), 30-oxo-lupeol (6), maslinic acid (7), 23-hydroxyursolic acid (8), β-amyrenone (9), acacetin (10), chrysoeriol (11), jaceosidin (12), kumatakenin (13), isosakuranetin (14), taxifolin (15), lyoniresinol (16), medioresinol (17), and balanophonin (18). Compounds 1-9 were triterpenoids, compounds 10-15 were flavonoids and compounds 16-18 were lignans. Conclusion: All compounds are isolated from the genus Scyphiphora for the first time.
ABSTRACT
Objective: To study the chemical constituents of Ledum palustre. Methods: Compounds were isolated from n-hexane fraction in the ethanol extract from L. palustre by silica gel column chromatography and HPLC. The structures of the chemical constituents were identified by analysis on their spectral data. Results: Thirteen compounds were isolated from n-hexane fraction in the ethanol extract from L. palustre and identified as euphol acetate (1), lanosta-8, 24-dien-3-one (2), taraxerol (3), labda-8(17), 14-dien-13-ol (4), (24S)-stigmast-4-en-3-one (5), euphol (6), isopimaric acid (7), larixyl acetate (8), 28-hydroxyl-lupenone (9), β-sitosterol (10), isocalamendiol (11), erythrodiol (12), and uvaol (13). Conclusion: Compounds 2, 4-9, 11, and 12 are first obtained from the plants of Ledum L.