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Chinese Pharmaceutical Journal ; (24): 2026-2028, 2012.
Article in Chinese | WPRIM | ID: wpr-860534

ABSTRACT

OBJECTIVE: To develop a method for the determination of ethanol extracts content of Pogostemon cablin (Blanco) Benth. using near-infrared spectroscopy. METHODS: The ethanol extracts contents of 139 samples were determined by the method of ethanol cold-soak extraction. Near-infrared spectrograms were obtained, then multiplicative signal correction, first derivative method and Savitzky-Golay filter method were used to process the spectrograms, at last the calibration model of ethanol extracts content was established by partial least squares regression analysis method. RESULTS: The correlation coefficients, root-mean-square error of calibration, root-mean-square error of prediction and root-mean-square error of cross-validation of the calibration model of ethanol extracts content were 0.98958, 0.590, 0.623 and 0.97518, respectively. CONCLUSION: The method is stable, accurate, and can be used to predict ethanol extracts content of Pogostemon cablin (Blanco) Benth. rapidly.

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