Torus mandibular e palatino predisponentes em um grupo familiar: fatores genéticos e ambientais, relato de uma série de casos / Mandibular and palatine torus predisposing in a family group: genetic and environmental factors, report of a series of cases / Torus mandibular y palatino predisponente en un grupo familiar: factores genéticos y ambientales, informe de una serie de casos

As exostoses mais conhecidas são o Torus palatino e mandibular, que se desenvolvem a partir do crescimento benigno da cortical óssea, localizadas respectivamente na linha média palatina e superfície lingual de caninos e pré-molares, podendo ser unilaterais ou bilaterais. Esse trabalho tem como objetivo o estudo de um grupo familiar que apresentaram o Torus como característica em comum, buscando confirmar a presença e prevalência das características clínicas multifatoriais listadas na literatura, possibilitando o diagnóstico da etiologia e assim traçando um plano de tratamento individual, se necessário. Como metodologia, foi realizada uma triagem com cada membro familiar na clínica Odontológica da Faculdade Sete Lagoas - FACSETE, descartando a participação no estudo os membros que não apresentaram o Torus. Os indivíduos que apresentaram indicação da remoção cirúrgica foram encaminhados para clínica de cirurgia da própria instituição. Concluímos, portanto, com este estudo que fatores genéticos e ambientais colaboram como fator etiológico mais predominantes para surgimento do Torus no grupo familiar estudado... (AU)

The best known exostosis are the palatine and mandibular Torus, which develop from the benign growth of the cortical bone, located respectively in the midpalatal line and lingual surface of canines and premolars, and maybe unilateral or bilateral. This work aims to study a family group that had Torus as a common feature, confirming the presence and prevalence of multifactorial clinical features listed in the literature, enabling the diagnosis of etiology and thus outlining an in dividual treatment plan, if necessary. As a methodology, a screening was performed by each family member at the Dental Clinic of Facul dade Sete Lagoas - FACSETE, discarding the participation in the study for members who did not present Torus. Individuals who indicated surgical removal were referred to the institution's own surgery clinic. Therefore, we conclude with this study that genetic and environmental factors collaborate as the most predominant etiological factor for the emergence of Torus in the studied family group... (AU)

Las exostosis más conocidas son el Torus palatino y el Torus mandibular, las cuales se desarrollan a partir del crecimiento benigno del hueso cortical y están ubicadas respectivamente en la línea medio palatina y en la cara lingual de los caninos y de los premolares que pueden ser unilaterales o bilaterales. Este proyecto tiene como objetivo el estudio de un grupo familiar que presentó en sus características comunes el Torus, buscando confirmar la presencia y el predominio de las características clínicas multifactoriales listadas en la literatura, lo que hizo posible el diagnóstico de la etiología y diseñar un plan de tratamiento individual, caso necesiten. Como la metodología fue hecho una selección con los miembros de la familia en la clínica odontologica de la Faculdade Sete Lagoas - FACSETE, quitando de los estudios las personas de la familia que no presentaron el Torus. Los individuos que presentaron indicación de extirpación quirúrgica fueron enviados a la clínica de cirugía de la escuela. Concluimos con este estudio que los factores genéticos y ambientales colaboraron como los factores etiológicos más predominantes para la aparición del Torus en la familia analizada... (AU)

Advances in epigenetic changes induced by pathogenic factors of oral diseases / 口腔疾病防治

@#The oral cavity is a complex and complete ecosystem. In addition to the microbial community, anatomical structure, temperature, humidity, pH, nutrient sources, proteases, and external factors all influence the ecosystem. Under normal circumstances, this ecosystem maintains a dynamic balance with the host. However, due to the large number of influencing factors, this dynamic balance is fragile. Abnormal changes in a certain factor can disrupt this balance and cause oral cavity disease. Increasing studies have confirmed the role of genetic factors in the etiology of oral diseases. With the understanding of the pathogenesis of oral diseases, the pathogenic factors induced by oral diseases have attracted more attention. This article reviews the key role of epigenetic changes induced by pathogenic factors, such as bacteria, viruses, and cytokines, in the pathogenesis of oral diseases and contributes to the development and application of related drugs.

Etiological factor distribution in elderly outpatients with vertigo/dizziness / 中华老年医学杂志

Objective To clarify the distribution of etiological factors in elderly versus non-elderly outpatients with vertigo/dizziness for optimizing the diagnosis and therapy. Methods We retrospectively analyzed data of outpatients with vertigo/dizziness in Shaanxi Provincial People's Hospital from April 2015 to April 2017 and conducted diagnoses in accordance with the currently wide-accepted diagnostic criteria. Results A total of 3 356 patients with chief complains of vertigo/dizziness were recruited ,and their top seven etiological factors were benign paroxysmal positional vertigo (n＝ 1 320 ,39.3%) ,chronic subjective dizziness(n＝680 ,20.3%) ,vestibular migraine(n＝386 ,11.5%) ,posterior circulation ischemia (n＝213 ,6.4%) ,Meniere's disease (n ＝ 138 ,4.1%) ,vestibular neuritis (n＝ 121 ,3.6%) ,and vestibular paroxysmia(n＝76 ,2.3%). The top four etiological factors for the elderly patients (n＝1 255)were benign paroxysmal positional vertigo (n＝ 498 ,39.7%) ,chronic subjective dizziness (n＝ 279 ,22.2%) ,posterior circulation ischemia(n＝161 ,12.8%) ,and vestibular migraine(n＝73 ,5.8%) ;while the top four etiological factors for non-elderly patients (n＝ 2 101)were benign paroxysmal positional vertigo (n＝ 822 ,39.1%) , chronic subjective dizziness(n＝401 ,19.1%) ,vestibular migraine(n＝313 ,14.9%) ,and vestibular neuritis(n＝105 ,5.0%). The detection rate in elderly patients versus non-elderly patients was significantly higher in chronic subjective dizziness (22.2% vs.19.1%,P＝ 0.032 )and in posterior circulation ischemia (12.8%vs.2.5%,P＝0.000) ,and was significantly lower in vestibular neuritis (1.3% vs.5.0%,P＝ 0.000 ) ,in vestibular migraine(5.8% vs.19.4%,P ＝ 0.000)and in other causes (1.0% vs.2.7%,P ＝ 0.002) . Conclusions The ratio of posterior circulation ischemia is markedly higher in elderly outpatients than in non-elderly outpatients ,whereas the ratios of vestibular migraine and vestibular neuritis in elderly patients are lower than in non-elderly outpatients.

Analysis of 124 cases of placental abruption and its early diagnosis / 重庆医学

Objective To analyze the clinical manifestations of placental abruption ,and try to provide evidence‐based data for early diagnosis .Methods Retrospective cases of placental abruption from January 2008 to March 2014 were analyzed ,the clinical characteristics ,etiological factor and outcomes were compared .Results There were 58 cases in Ⅰ degree ,45 cases in Ⅱ degree and 21 cases in Ⅲ degree .The incidence of PIH in Ⅰ degree group was significantly lower than that in Ⅱ degree group ,the incidence of PROM in Ⅰ degree group was significantly higher than that in Ⅱ and Ⅲ degree groups(P< 0 .05) .The main symptoms of Ⅰ degree group were vaginal bleeding .The main performances of Ⅱ and Ⅲ degree group were abdominal pain with or without vaginal bleed‐ing .The cesarean section rate of Ⅰ degree group was significantly lower than that of Ⅲ degree group ,and the rate of maternal‐fetal adverse outcomes was statistically lower than Ⅱ and Ⅲ degree groups (P< 0 .05) .Conclusion It is helpful for early diagnosis of placental abruption and improving prognosis by regular prenatal care ,analyzing and combining with history or risk factors ,ultra‐sound ,physical examination ,and paying attention to clinical performance like abdominal pain and vaginal bleeding ,as well as impro‐ving the ability to identify the abnormal FHR .

Anterior pituitary hypofunction: a clinical analysis of 117 cases / 中华内分泌代谢杂志

Objective To investigate the clinical features of anterior pituitary hypofunction.Methods A retrospective analysis was carried out on the data of 117 patients with anterior pituitary hypofunction during 1994-2010.Results There were 60.68％ male and 39.32％ female patients respectively.The onset age was from 13 to 79 years,with 79.12％ of the patients more than 40 years old.There were 57 cases with sellar tumors ( 40.17％ ),in which 55 cases( 96.49％ )were operated and (or) treated with radiotherapy.35 cases were operated via the frontal approaches( 66.04％ ) and 18 cases underwent transsphenoidal surgery ( 33.96％ ).There were 108 cases with hyponatremia with the first symptoms of weakness,anorexia,nausea,and vomiting induced by ACTH deficiency (92.31％ ).There were 23 cases accompanied with central diabetes insipidus( 19.66％ )and 82 cases with coronary heart disease( 70.09％ ).Conclusion Owing to the difference in etiological factors,the incidence,early symptoms,and the hormones involved are greatly different.The main cause is pituitary tumor,which occured more in aged person,more in males than females.

Advance in Research of Sub-health(review) / 中国康复理论与实践

@#To improve human cognition of sub-health condition by analyzing current situation of sub-health researches,the authors of this article reviewed the concept of sub-health,etiological factor,epidemiology,diagnostic code and other sides.

Analysis on latent etiological factor of deep venous thrombosis in lower limb / 重庆医科大学学报

Objective:To improve the diagnostic level of lower extremity deep venous thrombosis ( LEDVT ) and decrease the rate of missed diagnosis.Methods:23 clinical cases which admitting diagnosed with LEDVT but final diagnoses weren't LEDVT were retrospectively analyzed in our hospital between 2000 and 2006.Results:Of these 23 cases with missed diagnosed,13 cases were gynecology tumor,1 case was adenomyosis,3 cases were rectal cancer,2 cases were lung cancer,2 cases were carcinoma of bladder,1 case was prostatic carcinoma,and 1 case was malignant lymphoma in ingina.Conclusion:clinicians should pay attention to question the case history when their patients get lower extremity deep venous thrombosis,especially to those whom are inconspicuous predisposing cause.

Investigation of cervical spongdylotic amyrotryphy / 中国矫形外科杂志

Cervical spondylotic amyotrophy is receiving increasing attention in recent years as a class of specificity of cervical spondylosis,this paper refers a large number of reference reported in the literature,and gives an accurate summary of the disease from the basic definition of disease,pathogenic factors,clinical manifestations,diagnostic criteria and prognostic point of view,and provides a theoretical foundation for clinical diagnosis and treatment of cervical spondylotic amyotrophy.

Analysis of the causes of the 583 cases of hip fracture / 中国矫形外科杂志

[Objective]To study the tendency of hip fracture by analyzing morbidity factors to provide an basis for preventing the fracture.[Method]All of the case records of hip fractures treated at west china hospital between 2000-1 and 2005-12 were checked and 583 inpatients were selected for analysis.[Result]The major injury cause was fall in the old and female was more susceptible.High energy injury was the major cause in younger 50. Osteoporosis and fall contributed best to the hip fracture in elderly.Concomitant disease and environmental factors increased the risk.[Conclusion]Osteoporosis and fall contribute most to the hip fracture in elderly,accordingly,to prevent fall and osteoporosis is vital to the old.

Clinical Analysis of the Etiological Factors and Prognosis of 347 Pregnant Women with Liver Dysfunction / 医学研究杂志

Objective To investigate the etiological factors of hepatic dysfunction during late gestational period,and explore its effect on the mothers and babies.Methods The causes and prognosis of 347 cases with hepatic dysfunction during gestational period were retrospectively analyzed.Result Of the 347 cases of pregnancy,viral hepatitis was present in 216 cases(62.2%),and intrahepatic cholestasis of pregnancy(ICP) present in 80 cases(23.1%);Postpartum hemorrhage rate increased significantly in viral hepatitis,and the rates of premature birth,fetal distress in uterus and cesarean increased obviously in ICP.Conclusion Viral hepatitis and ICP were the main causes of hepatic dysfunction,different complicated diseases may increase the danger of the mother and baby during pregnancy and childbirth.

Syndrome Analysis and Etiological Factor Survey of 122 Patients with Premature Ovarian Failure / 中国中医药信息杂志

Objective To explore the TCM syndrome and its distribution regularity of premature ovarian failure(POF) as well as the relation between the etiological factor and TCM syndrome of it.Methods The pathogenetic condition and etiological factor of 122 patients with POF were surveyed,and TCM syndrome differentiation was carried out on them.Results The TCM symptoms of POF manifested the tendency of variety.Among the 122 cases,Gan-stagnation and Shen-deficiency type accounted for 33.61% of them,Gan-Shen yin deficiency type for 18.03%,Pi-Shen yang deficiency type for 15.57%,Jin damage due to excessive heat type for 15.57%,Shen-deficiency blood stasis type for 8.20%,and Gan-stagnation and Pi-deficiency type for 7.38%.The influence of modern living environment and life style to the disease was found in 68.03% of the patients’ case history.31.15% of the patients was induced by emotion,31.97% by drugs and disease,and 4.92% by both of them.In patients induced by emotion,the proportion of Gan-stagnation and Shen-deficiency type was the highest as compared with the other types(P0.05).Conclusion Gan-stagnation and Shen-deficiency type,Gan-Shen yin deficiency,Pi-Shen yang deficiency type and Jin damage due to excessive heat are the commonly encountered syndromes in patients with POF.Besides the congenital,Shen-Qi and Chong-Ren Qi-blood insufficiency as well as the genetic factor,the modern living environment and life style have the promotion in the genesis of POF.

A study on the etiology of gastric eosinophilic granuloma / 中国实用内科杂志

Objectives To investigate the etiological factors of gastric eosinophilic granuloma(GEG).Methods Clinical manifestations,histopathological features, diagnosis and treatment were analysed retrospectively.Reformed Giemsa staining was employed to detect the helicobacter pylori in 23 patients.Results There was a significant sex difference in patients with GEG. And the misdiagnosis was quite high before resection. Lymphoid follicles were found in 68 8% of the lesion tissues and helicobacter infection was detected in 69 6% of the patients. Increased eosinophils in peripheral blood was observed in 11 patients.Conclusions Helicobacter infection, estrogen and allergic reaction may be related to the development of GEG.

Three dimensional analysis of the occlusion in patients with temporomandibular disorders / 实用口腔医学杂志

Objectives: To investigate the occlusion features in thre e dimensions in patients with temporomandibular disorders(TMD). Methods: Occlusal casts were obtained from 23 asymptom volunteers and 101 TMD pati ents and were analyzed in three dimensions by scores vertically, mesio-distally and labial-or buccal-lingually. Bilateral TMJs of each TMD patient was examin ed with Schuller's radiograph and tomograph, the sounding TMJs were examined wit h arthrography. The relationship between occlusion scores and the changes shown in X-ray images were analyzed. Results: 66.3% TMD patients had abnormal occlusion in vertical direction.Abnormal occlusion in vertical directio n was correlated with TMD symptoms(P 0.05 ). Conclusion: Abnormal occlus ion in vertical direction is correlated with TMD symptoms.

Clinical investigation on giant gastric ulcer for rare etiological causes / 中华消化杂志

Objective To investigate rare etiological causes of giant gastric ulcers. Methods A retrospective investigation was made on 4986 endoscopically proved giant gastric ulcer in our hospital, from January 1976 to December 2000. The morphological features under endoscopy, pathology, diagnosis, treatment and prognosis were analyzed in 59 giant gastric ulcers with special causes. Results Thirty two cases of gastric eosinophilic granuloma,8 gastric carcinoid tumor,8 gastric schistosomiasis, 5 gastric Crohn's disease,4 gastric lymphoma and 2 gastric Behcet's disease were identified. Ten gastric eosinophilic granuloma,3 gastric carcinoid tumor,3 gastric schistosomiasis, 5 gastric Crohn's disease,3 gastric lymphoma , 1 gastric Behcet's disease were misdiagnosed at initial endoscopy.Conclusions Rare etiological causes of giant gastric ulcers could be divided into 3 categories: non-epithelium gastric tumor, gastric granulomatous disease and gastric vascular disease. Careful observation ulcer endoscopy, history inquiry, physical examination, comprehensive analysis and laboratory examination may provide useful information for the diagnosis. Biopsy may be falsely negative in some cases.

Screening and Study on Etiology for Neonatal Congenital Hypothyroidism in Henan Province / 实用儿科临床杂志

Objective To investigate the screening state and cause of neonatal congenital hypothyroidism(CH) in Henan province.Me-thods Three hundred and thirty-eight thousands no-choice newborns in the 156 hospitals in Henan province from Jan.1998 to Dec.2004 were received screening.The heel peripheral blood samples were taken and the levels of thyroid-stimulating hormone(TSH) were mea-sured by time-resolved fluoroimmunoassay.Positive newborns were recalled and draw out 2 mL venous blood.The levels of TSH,triiodothyronine(T3) and thyroxine(T4) in serum were detected by direct chemiluminescence.The abnormal criterion was that the level of T3,T4 was under the normal range and the level of TSH was above the normal range.Meanwhile their growth and development,intelligence quotient,related medical examination and family histories were investigated in order to find etiological factors and high risk factors.Results The average coverage rate was 5.93% of neonatal screening for CH in Henan province.One hundrend and nine infants were diagnosed CH.The attack rate was about 0.032%.The site and growth of thyroideas of 109 cases with CH were all normal.There were higher morbidity for pregnant women with unhealthy condition or the families with hypertension,diabetes,deformity or dysnoesia.Conclusions Etiology of newborns with CH in Henan province may be not relate with congenital absence and dystopia of thyroidea,but relate with dyssynthesis and receptor deficiency of hormone.And scientific reference is offered for the further study.