Hand Anthropometry of Italian Elite Male Swimmers / Antropometría de la Mano en Nadadores Italianos Masculinos de Élite

SUMMARY: Hand size is part of the anthropometric parameters that are assessed in swimmers to select elite athletes, as certain anthropometric relationships involving hand measurements are significantly correlated with sports performance in various swimming disciplines. The authors present the results of the anthropometric study carried out on the hands of 15 elite male Italian swimmers from to the Italian national open water swimming team. All swimmers participated at least once in World Cup and Absolute Italian Championships, winning at least one medal in their sporting career. In particular, the sample includes a medallist at the World Championships, a winner of the World Cup ultra swim marathon circuit and medallists at the European Championships. The sample consisted of 15 elite male swimmers with a mean age of 28.93 years. The following anthropometric measurements were taken on each athlete: Stature; weight; seven dimensions on each hand: hand length; hand breadth metacarpal; palm length; middle finger length; index finger length; thumb distance; and the distance from the thumb root to first flexure line of the index finger - trigger length. The size of the hands is an important factor in the swimmer's propulsion and push as a larger hand allows for greater support in the water and consequently generates more resistance. The anthropometric characteristics of the hands of Italian swimmers are missing from the anthropometric data already reported in the literature and can be used to make comparisons with elite athletes from other nations. Furthermore, anthropometric measurements could be used as predictors to estimate the swimmers' chance of success.

El tamaño de la mano es uno de los parámetros antropométricos que se evalúan en los nadadores para seleccionar a los deportistas de élite. Los autores presentan los resultados de un estudio antropométrico realizado en las manos de 15 nadadores italianos masculinos de élite pertenecientes al equipo nacional de natación en aguas abiertas. Todos los nadadores participaron al menos una vez en Copas del Mundo y Campeonatos de Italia, ganando al menos una medalla en su carrera deportiva. En concreto, la muestra incluye un medallista en los Campeonatos del Mundo, un ganador de la Copa del Mundo del circuito de ultra maratón de natación y medallistas en los Campeonatos de Europa. La muestra consta de 15 nadadores masculinos de élite con una edad media de 28,93 años. Se tomaron las siguientes medidas antropométricas a cada atleta: estatura; peso; siete dimensiones en cada mano: longitud de la mano, anchura de la mano en el metacarpiano, longitud de la palma, longitud del primer, segundo y tercer dedo, distancia entre la raíz del primer dedo y la primera línea de flexión del segundo dedo. El tamaño de las manos es un factor importante para la propulsión y el empuje del nadador, ya que una mano más grande permite un mayor apoyo en el agua y, en consecuencia, genera más resistencia. Las características antropométricas de las manos de los nadadores italianos faltan en los datos antropométricos recolectados en la literatura y pueden utilizarse para hacer comparaciones con los atletas de élite de otras naciones. Además, las medidas antropométricas podrían utilizarse como predictores para estimar las posibilidades de éxito de los nadadores.

New development of EU health strategy: Implementation characteristics and policy implications of EU Health / 公共卫生与预防医学

The EU is a joint political and economic community organization of many countries. The formulation and implementation of its health strategy need to take into account the differences in the development level of public health among its member countries. Since 2003, the EU has completed the implementation of the third-generation health strategy and launched the fourth-generation health strategy in June 2021. Compared with previous generations of health strategies, EU4Health not only includes targeted measures to cope with COVID-19, but also analyzes the current health challenges in the EU, pointing out the direction for the future development of health in the EU. By introducing the basic health situation of the EU, sorting out the development process, content, and strategic indicators of the EU health strategy, and analyzing the implementation characteristics of EU4Health in the EU, this article aims to provide inspiration for the implementation and further improvement of the “Healthy China” strategy.

Applicability of the acute leukemia (AL) - EBMT score as a prognostic model for allogeneic hematopoietic stem cell transplantation: a single-center, prospective, cohort study at a reference transplant center in Brazil

Abstract Introduction The Acute Leukemia-European Society for Blood and Marrow Transplantation (AL-EBMT) risk score was recently developed and validated by Shouval et al. Objective To assess the ability of this score in predicting the 2-year overall survival (OS-2), leukemia-free survival (LFS-2) and transplant-related mortality (TRM) in acute leukemia (AL) adult patients undergoing a first allogeneic hematopoietic stem cell transplant (HSCT) at a transplant center in Brazil. Methods In this prospective, cohort study, we used the formula published by Shouval et al. to calculate the AL-EBMT score and stratify patients into three risk categories. Results A total of 79 patients transplanted between 2008 and 2018 were analyzed. The median age was 38 years. Acute myeloid leukemia was the most common diagnosis (68%). Almost a quarter of the cases were at an advanced stage. All hematopoietic stem cell transplantations (HSCTs) were human leukocyte antigen-matched (HLA-matched) and the majority used familial donors (77%). Myeloablative conditioning was used in 92% of the cases. Stratification according to the AL-EBMT score into low-, intermediate- and high-risk groups yielded the following results: 40%, 12% and 47% of the cases, respectively. The high scoring group was associated with a hazard ratio of 2.1 (p= 0.007), 2.1 (p= 0.009) and 2.47 (p= 0.01) for the 2-year OS, LFS and TRM, respectively. Conclusion This study supports the ability of the AL-EBMT score to reasonably predict the 2-year post-transplant OS, LFS and TRM and to discriminate between risk categories in adult patients with AL, thus confirming its usefulness in clinical decision-making in this setting. Larger, multicenter studies may further help confirm these findings.

A exigência do esporte de alta-competição e o desenvolvimento pleno dos atletas: a necessidade de uma relação simbiótica / The demands of high-competition sport and the full development of athletes: the need for a symbiotic relationship / Las exigencias del deporte de alta competición y el desarrollo pleno de los deportistas: la necesidad de una relación simbiótica

RESUMO O presente ensaio discute a Dupla Carreira (DC) em contexto europeu e a natureza simbiótica das habilidades adquiridas ao longo da vida, contribuindo para uma transição saudável ao mercado de trabalho no final da carreira esportiva. Nessa esteira evolutiva do suporte à DC fica evidente a produção conjunta do conhecimento em nível regional, nacional e internacional entre os Estados-Membros da União Europeia, assim como a proposição de políticas de amparo tanto aos atletas estudantes quanto aos atores que participam do processo de DC. A apresentação das Diretrizes para a DC em conjunto com os programas More Than Gold e EMPATIA ressaltam a importância do suprimento a nível micro, meso e macroestrutural, fornecendo experiências que induzem à ampliação do conceito de atleta estudante para sportsperson.

ABSTRACT This essay discusses the dual career (DC) in a European context and its symbiotic nature present in the skills acquired throughout life that contribute to a healthy transition to the job market at the end of the sports career. In this evolutionary path of DC support, the joint production of knowledge at a regional, national and international level, between the member states of the European Union, is evident, as well as the proposal of policies to support student athletes, and actors who participate in the DC process. The presentation of the Guidelines for DC and the More Than Gold and EMPATIA programs highlight the importance of supply at the micro, meso and macro structural level, experiences that induce the expansion of the concept of student athlete to sportsperson.

RESUMEN Este ensayo analiza la carrera dual (DC) en un contexto europeo y su naturaleza simbiótica presente en las habilidades adquiridas a lo largo de la vida que contribuyen a una transición saludable al mercado laboral al final de la carrera deportiva. Por lo tanto, el apoyo al DC destaca la producción conjunta de conocimiento a nivel regional, nacional e internacional, entre los estados miembros de la Unión Europea, así como la propuesta de políticas para apoyar a los estudiantes deportistas y actores que participan en el proceso de DC. La presentación de los Lineamientos para DC y los programas Más Than Gold y EMPATHY resaltan la importancia de ofrecer a nivel micro, meso y macro estructural, experiencias que induzcan a ampliar el concepto de estudiante deportista a sportsperson.

Health-related quality of life in patients with type 2 diabetes based on the European 5-Dimensional Health Scale / 公共卫生与预防医学

Objective To evaluate the quality of life of patients with type 2 diabetes mellitus in Weifang City, Shandong Province and to explore its influencing factors. Methods A multistage stratified random sampling method was used to investigate patients in endocrine outpatient clinics in four medical institutions in Weifang from July to September 2022. The survey included general information, multi-dimensional evaluation of quality of life with the EQ-5D-5L scale, calculation of health utility values, and analysis of influencing factors using Tobit regression models. Results A total of 397 patients with type 2 diabetes were included in the present investigation, with health utility value of 0.82±0.21 points and visual analogue scale (VAS) score of 79.47±12.81 points. Pain or discomfort, anxiety or depression were more prominent in the study population. Age, diabetic complications, BMI, daily need for care, social support, and daily level of glycemic control were factors influencing health-related quality of life in patients with type 2 diabetes. Conclusion In the actual treatment of type 2 diabetes patients, an emphasis should be placed on protecting elderly type 2 diabetic patients, preventing and controlling the occurrence and development of diabetic complications, and improving daily blood glucose control to further improve the health-related quality of life of the population.

Interpretation of the first edition of definition, diagnosis and treatment of oligometastatic oesophagogastric cancer: A Delphi consensus study in Europe / 中国胸心血管外科临床杂志

@#Local treatment improves the outcomes for oligometastatic disease, an intermediate state between locoregional and widespread disease. However, consensus about the definition, diagnosis and treatment of oligometastatic oesophagogastric cancer is lacking. The first edition "Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer: A Delphi consensus study in Europe" was published on February 15, 2023 by 65 European medical specialists. In this article, the consensus will be interpreted to provide new idea for the diagnosis and treatment of oligometastatic oesophagogastric cancer for Chinese clinicians.

Highlights of the 29th European Congress on Obesity(2022) / 中华内分泌代谢杂志

The 29th European Congress on Obesity(ECO) was held in Maastricht, Netherlands from May 4 to May 7, 2022. The conference consisted of five sections with a great amount of information: basic science, behavioural and public health, childhood and adolescent obesity, management and intervention, and metabolic surgery, with a total of more than 80 special reports. We summarized the epidemiological investigation, diagnosis, complications and management of obesity, aiming to provide reference information for the comprehensive management of obesity in China.

The application of the Chinese version of the European quality of life five-dimension scale in China / 中国医师进修杂志

This paper introduces the composition of the Chinese version of the European quality of life five-dimension scale (EQ-5D), including two different level scales, EQ-5D-3L and EQ-5D-5L, and summarizes the status quo of the application of the above scales. This paper sorts out the utility value sets of the EQ-5D-3L and EQ-5D-5L scales currently developed based on the Chinese population, and provide an important reference for Chinese researchers to choose suitable scales for research on health-related quality of life and health economics cost-utility analysis in the future.

Validation of genome-wide association studies (GWAS)-identified type 2 diabetes mellitus risk variants in Pakistani Pashtun population / Journal of the ASEAN Federation of Endocrine Societies

Objective@#Recent GWAS largely conducted in European populations have successfully identified multiple genetic risk variants associated with Type 2 Diabetes Mellitus (T2DM). However, the effects conferred by these variants in the Pakistani population have not yet been fully elucidated. The objective of this study was to examine European GWAS- identified T2DM risk variants in the Pakistani Pashtun population to better understand the shared genetic basis of T2DM in the European and Pakistani cohorts.@*Methodology@#A total of 100 T2DM patients and 100 healthy volunteers of Pashtun ethnicity were enrolled in this study. Both groups were genotyped for 8 selected single nucleotide polymorphisms (SNPs) using the Sequenom MassARRAY® platform. The association between selected SNPs and T2DM was determined by using appropriate statistical tests.@*Results@#Of the 8 studied SNPs, 5 SNPs, SLC30A8/ rs13266634 (p=0.031, OR=2.13), IGF2BP2/ rs4402960 (p=0.001, OR=3.01), KCNJ11/ rs5219 (p=0.042, OR=1.78), PPARG/ rs1801282 (p=0.042, OR=2.81) and TCF7L2/ rs7903146 (p=0.00006, 3.41) had a significant association with T2DM. SNP GLIS3/ rs7041847 (p=0.051, OR=2.01) showed no sufficient evidence of association. SNPs KCNQ1/ rs2237892 (p=0.140, OR=1.61) and HHEX/IDE/ s1111875 (p=0.112, OR=1.31) showed opposite allelic effects and were not validated for T2DM risk in the study population. Among the studied SNPs, TCF7L2/ rs7903146 showed the most significant association.@*Conclusion@#Our study finding indicates that selected genome-wide significant T2DM risk variants previously identified in European descent also increase the risk of developing T2DM in the Pakistani Pashtun population.

Un caso de publicación en revista médica pirata / A case of publication in a predatory medical journal

Las revistas piratas o depredadoras (predatory journals en inglés) son cada vez más frecuentes y sorprenden en su buena fe a investigadores/as que buscan publicar sus manuscritos. Este artículo presenta un caso de descubrimiento y demostración de publicación en una revista pirata y un conjunto de sugerencias para evitar este error, como un aporte a profesionales de ciencias de la salud que realizan actividades de investigación. El resultado de las investigaciones mostró que la revista European Journal of Gynaecological Oncology(EJGO) es una revista pirata: fundada en 1980, solo desde 2020 posee International Standard Serial Number (ISSN) digital: sus primeras editoras, hasta 2020, no trabajaban en el área disciplinar de la revista ni pudieron ser rastreadas en ORCID; su actual editor no responde correos; la dirección postal de la editorial es la misma de una empresa canadiense importadora de juguetes. Hasta 2021 no poseía una plataforma web para el envío del manuscrito sino se enviaba el trabajo a un correo electrónico genérico. A raíz de nuestras denuncias fue suspendida de Scopus (Scimago) y Clarivate (Web of Science). Cuando Clarivate forzó a EJGO a avisar a sus lectores que estaba suspendida, inmediatamente cambió su página web y la empresa editora. En síntesis, se muestra un caso real de publicación en una revista pirata, la detección y comprobación de que dicha revista efectivamente cae en esta categoría y el aporte de conceptos y definiciones para tener en cuenta a fin de evitar caer en este error. (AU)

Predatory journals are becoming more frequent every day and surprise researchers who seek to publish their manuscripts. This article presents a case of discovery and demonstration of publication in a predatory journal and a set of suggestions to avoid this error, in a contribution to the education of health science professionals. The result of the research showed that the European Journal of Gynaecological Oncology (EJGO) is a pirate journal: founded in 1980, it obtainthe digital International Standard Serial Number (ISSN) in 2020; its former editors, until 2020, do not work in the disciplinary area of the journal and could not be tracked in ORCID, the new editor did not respond any mail; the postal address of the publisher is the same as that of a Canadian toy import company. Until 2021, it did not have a web platform for sending the manuscript, but rather the work was sent to a generic email. As a result of our complaints, it was suspended from Scopus (Scimago) and Clarivate (Web of Science).When Clarivate forced EJGO to notify its readers that it was suspended, it immediately changed its website and publisher. In brief, a real case of publication in a predatory journal is shown, the detection and verification that this journal actually falls into this category and contribution of concepts and definitions to avoid falling into this error. (AU)

Interoperabilidade europeia de registos de saúde eletrónicos e segurança do paciente / European interoperability of electronic health records and patient safety / Interoperabilidad europea de historias clínicas electrónicas y seguridad del paciente

Os registos de saúde são um elemento-chave na prestação de cuidados de saúde desempenhando diversos objetivos. Um dos mais importantes é, sem dúvida, assegurar a segurança dos pacientes na continuidade da prestação desses cuidados de saúde. A Europa encontra-se a desenvolver importantes passos nesse sentido com a adoção de legislação futura que pretende assegurar, entre outras coisas, a interoperabilidade dos sistemas de registo dos dados clínicos a uma dimensão europeia.

Health records are a key element in health care and fulfill several objectives. One of the most important is undoubtedly to ensure patient safety in the continuous delivery of healthcare. Europe is taking important steps in this direction with the adoption of future legislation that will, among other things, ensure the interoperability of clinical data recording systems at the European level.

Los registros de salud son un elemento clave en la prestación de atención en salud, cumpliendo varios objetivos. Uno de los más importantes es, sin duda, garantizar la seguridad de los pacientes en la continuidad de la prestación de esta asistencia sanitaria. Europa está dando pasos importantes en esta dirección con la adopción de una futura legislación que pretende garantizar, entre otras cosas, la interoperabilidad de los sistemas de registro de datos clínicos con dimensión europea.

Eficacia de los sistemas en superioridad e igualdad númerica en balonmano: panorama de una competeción europea

Petroni de Senzi Barreira, C., da Silva Musa, V., Pereira Morato, M. y Pombo Menezes, R. (2022). Eficacia de los sistemas defensivos en superioridad e igualdad numérica en balonmano: panorama de una competición europea. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 20(1), 1-13. Las acciones realizadas durante la fase defensiva en balonmano pueden ser determinantes para los resultados de los partidos, y los análisis en esta fase permiten identificar aspectos clave que pueden ayudar en la planificación y entrenamiento de los equipos. El objetivo de este trabajo fue analizar la influencia de las relaciones numéricas en sistemas defensivos cerrados y abiertos en partidos de balonmano de alto nivel. Se analizaron doce partidos del Campeonato de Europa de clubes de Balonmano, cuyo instrumento de análisis permitió identificar la relación numérica del juego (superioridad defensiva o igualdad) y cuantificar los resultados (GO: gol; NG: sin gol; PP: perdida del balón) y regiones de la cancha en las que terminaron las acciones ofensivas. Se utilizó el chi-cuadrado para el análisis de datos. Los resultados mostraron similitudes para la realización del ataque a través de situaciones de igualdad con el uso de sistemas cerrados (GO = 47.3%; NG = 33.6%; PP = 19.1%) y sistemas abiertos (GO = 46.0%; NG = 34.3%; PP = 19.7%). Para esta situación, se demostró que el uso de sistemas cerrados provoca la pérdida del balón más lejos de la portería (9m- = 56.9%; 9m + = 43.1%), cuando se compara con el uso de sistemas abiertos (9m- = 64.5%; 9m + = 35.5%). En superioridad numérica defensiva, el uso de sistemas abiertos (GO = 28.6%; NG = 53.6%; PP = 17.9%), en comparación con sistemas cerrados (GO = 49.3%; NG = 29.6%; PP = 21.1 %), mostró mayor efectividad en los resultados de las acciones. Además, las secuencias terminaron más lejos del objetivo cuando se utilizaron sistemas abiertos (9m- = 42.9%; 9m+ = 57.1%), en comparación con sistemas cerrados (9m- = 68.3%; 9m+ = 31.7%). Se concluyó que la elección del sistema defensivo debe basarse en el modelo de juego del equipo y en las relaciones recurrentes del juego, especialmente en situaciones de igualdad numérica (más frecuentes). Sin embargo, cuando se tiene una ventaja numérica defensiva, limitar el espacio y el tiempo para que los atacantes tomen decisiones parece ser una estrategia eficaz.

Petroni de Senzi Barreira, C., da Silva Musa, V., Pereira Morato, M. y Pombo Menezes, R. (2022). Eficácia dos sistemas defensivos em superioridade e igualdade numérica no handebol: panorama de uma competição europeia. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 20(1), 1-13. As ações e escolhas realizadas durante a fase defensiva no handebol podem ser determinantes para os resultados das partidas. Análises abordando essa fase do jogo vêm sendo realizadas para identificar aspectos determinantes e que possam auxiliar no planejamento e treinamentos das equipes. Este estudo teve como objetivo analisar a influência das relações numéricas nos sistemas defensivos fechados e abertos no handebol de alto nível. Para isso foram analisados 12 jogos do campeonato europeu de handebol de clubes, cujo instrumento de análise permitiu identificar a relação numérica do jogo (superioridade ou igualdade numérica defensiva) e quantificar os resultados (GO: gol; NG: não-gol; PP: perda de posse da bola) e os locais em que se encerraram as ações ofensivas. Foi utilizado o teste qui-quadrado para análise dos dados. Os resultados apontaram semelhanças para a conclusão do ataque mediante situações de igualdade com a utilização dos sistemas fechados (GO = 47.3%; NG = 33.6%; PP = 19.1%) e dos sistemas abertos (GO = 46.0%; NG = 34.3%; PP = 19.7%). Para essa situação, demonstrou-se que a utilização dos sistemas fechados provoca o encerramento da posse mais distante do gol (9m- = 56.9%; 9m+ = 43.1%), quando comparado à utilização dos sistemas abertos (9m- = 64.5%; 9m+ = 35.5%). Em situações de superioridade numérica defensiva a utilização dos sistemas abertos (GO = 28.6%; NG = 53.6%; PP = 17.9%), quando comparados aos sistemas fechados (GO = 49.3%; NG = 29.6%; PP = 21.1%), apresentou maior eficácia nos resultados das ações. Além disso, as sequências se encerraram mais distantes do gol quando foram utilizados sistemas abertos (9m- = 42.9%; 9m+ = 57.1%) em comparação aos sistemas fechados (9m- = 68.3%; 9m+ = 31.7%). Conclui-se que a escolha do sistema defensivo deve ser pautada no modelo de jogo da equipe e nas relações recorrentes do jogo, nos momentos de igualdade numérica (mais frequentes). Porém, em momentos de vantagem numérica defensiva limitar o espaço e o tempo para que os atacantes tomem decisões mostra-se como uma estratégia eficaz.

Petroni de Senzi Barreira, C., da Silva Musa, V., Pereira Morato, M. y Pombo Menezes, R. (2022). Efficiency of handball defensive systems in numerical equality and superiority: panorama of a european competition. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 20(1), 1-13. Actions taken during the defensive phase in handball can determine match results; therefore, analyzing this phase helps identify key aspects that can assist in team training and planning. The aim of this paper was to analyze the influence of numerical relations on closed and open defense systems in top level handball matches. Twelve matches of the European handball club championship were analyzed, which allowed us to identify the numerical relationship of the game (defensive superiority or equality) and quantify results (GO: goal; NG: non-goal; PP: loss of ball possession) and the sections of the court where offensive actions ended up. A chi-squared test was used for data analysis. Results showed similarities in terms of the attack's conclusion in numerical equality situations, when defense used closed systems (GO = 47.3%; NG = 33.6%; PP = 19.1%) and open systems (GO = 46.0%; NG = 34.3%; PP = 19.7%). For this situation, using closed systems results in losing ball possession further from the goal (9m- = 56.9%; 9m+ = 43.1%), when compared to open systems (9m- = 64.5%; 9m+ = 35.5%). In defensive numerical superiority, using open systems (GO = 28.6%; NG = 53.6%; PP = 17.9%), compared to closed systems (GO = 49.3%; NG = 29.6%; PP = 21.1%) gives more efficient results. In addition, sequences end further from the goal when open systems were used (9m- = 42.9%; 9m+ = 57.1%), compared to closed systems (9m- = 68.3%; 9m+ = 31.7%). It was concluded that the selection of the defensive system should be based on the team's game model and game relationships, especially in situations of numerical equality (more frequent). However, when in defensive numerical advantage, limiting the space and time for attackers to make decisions seems to be an effective strategy.

Biología comparada del conejo criollo (Sylvilagus sp.) y el conejo doméstico europeo (Oryctolagus sp.) con antecedentes de su consumo en una ciudad de Venezuela / Compared Biology of the Native Rabbit (Sylvilagus sp.) and the European Domestic Rabbit (Oryctolagus sp.) with a Background of Rabbit Consumption in a Venezuelan City

Resumen Las diferencias biológicas entre el conejo criollo Sylvilagus sp. (Lagomorpha: Leporidae) y el conejo europeo (Oryctolagus sp.) son poco conocidas entre cunicultores de Latinoamérica, bien sea porque la cunicultura es una explotación menor, comparada con las de otras especies de animales domésticos, o porque la enseñanza de esta materia en estudios universitarios es escaza. El objetivo central de esta investigación fue examinar comparativamente las diferencias existentes entre conejos Sylvilagus sp. y Oryctolagus sp., en relación con su biología, consumo y explotación comercial. Para ello se usó el sistema del metanálisis de trabajos científicos publicados sobre el tema, noticias de prensa y entrevistas realizadas a consumidores en el lapso del 2000 al 2019. Se tomaron en cuenta características morfológicas, fisiológicas, de origen genético y su comportamiento con relación al medio ambiente. Se organizaron y analizaron estas características para establecer las posibles semejanzas y diferencias entre ambos géneros. Como la familia Leporidae comprende tres géneros en Suramérica, se incluyó el género Lepus sp. solo en un cuadro comparativo de géneros. Se encontraron diferencias biológicas, genéticas y reproductivas significativas entre los géneros Sylvilagus sp. y Oryctolagus sp. que pueden ser imperceptibles para cunicultores inexpertos; por ende, se buscó hacer notar las características de cada género para su identificación práctica. Se determinó que el consumo de la carne de conejo depende de la disponibilidad que exista en el mercado.

Abstract Biologic differences between the native rabbit Sylvilagus sp. (Lagomorpha: Leporidae) and the European rabbit (Oryctolagus sp.) are quite unknown among Latin-American rabbit-breeders, either since rabbit-breeding is scarcely exploited as compared to other species of domestic animals or because this subject is taught very unusually in the college education. This research is aimed at examining comparatively the differences between Sylvilagus sp. and Oryctolagus sp. rabbits regarding their biology, consumption, and business exploitation. To do so, a meta-analysis was carried out on different scientific works dealing with this topic, news, and interviews to consumers during the term 2000 to 2019. Morphological, physiological, and genetic-origin characteristics were considered as well as how they behave in relation to the environment. These characteristics were organized and analyzed to determine the potential similarities and differences between both genuses. As the family Leporidae includes three genuses in South America, then the genus Lepus sp. was included only in a genus comparative table. Significant biologic, genetic and reproductive differences between Sylvilagus sp. And Oryctolagus sp. were found but they can be unnoticed to the unexpert rabbit-breeders. Therefore, characteristics typical to each genus were highlighted to allow a practical identification. It was determined that the consumption of rabbit meat depends on the availability in the market.

Fatherhood among adolescents in conflict with the law: A family systemic approach / Paternidad en adolescente en conflicto con la ley: una perspectiva desde la terapia familiar sistémica / Paternidade em adolescentes em conflito com a lei: uma perspectiva da terapia familiar sistêmica

Resumen (analítico) The objective of this paper was to analyze the construction of father-hood in adolescents who are in conflict with the law through an exploratory and qualitative study. Life stories were developed using the in-depth interview technique. The sample consisted of four adolescents in conflict with the law. Through interpretative content analysis, we obtained seven categories, including: emotional context of family origin, family functioning, witnessing family violence and the expression of masculinity by transgressing the law and using drugs. Paternity allows these young fathers to reflect on their own experiences during childhood and develop a paternal role during their transition process out of detention. The main role they assume in their paternity is that of provider, but they also make space to satisfy the affective needs of their children.

Abstract (analytical) El objetivo fue analizar la construcción de la paternidad en adolescentes en conflicto con la ley. Se llevó a cabo un estudio exploratorio y cualitativo, se construyeron historias de vida a través de la técnica de entrevista a profundidad. La muestra se conformó por cuatro adolescentes en conflicto con la ley. Se hizo un análisis de contenido interpretativo y se obtuvieron siete categorías: contexto emocional de la familia de origen, el funcionamiento familiar, ser testigo de violencia familiar y la expresión de masculinidad al transgredir la ley y usar drogas. La paternidad permite reflexionar acerca de sus experiencias en la infancia, desarrollar un rol paternal en transición, en el que asumen como principal función el proveer, pero dando espacio a satisfacer las necesidades afectivas de sus hijos.

Resumo (analítico) O objetivo foi analisar a construção da paternidade em adolescentes em conflito com a lei. Realizou-se um estudo exploratório e qualitativo, as histórias de vida foram construídas por meio da técnica de entrevista em profundidade. A mostra foi composta por quatro adolescentes em conflito com a lei. Por meio da análise de conteúdo interpretativa, obtivemos sete categorias: contexto emocional de origem familiar, funcionamento familiar, testemunho de violência familiar, expressão da masculinidade pela transgressão da lei e uso de drogas. A paternidade permite que reflitam sobre suas vivências na infância, desenvolvam um papel paternal em transição, em que assumem a função principal de prover, mas dando espaço para a satisfação das necessidades afetivas de seus filhos.

Estimación de la tasa de filtración glomerular: concordancia de la ecuación del European Kidney Function Consortium de 2020 con CKD-EPI y FAS en adultos jóvenes

Contexto: la TFG es un indicador de la función renal y se estima por ecuaciones TFGe, la mayoría son aplicables en un rango etario, aunque se producen discrepancias en los valores al cambiar de fórmula por cruzar un límite de edad. Así, la ecuación CKD-EPI sobreestima la TFG en adultos jóvenes, mientras que la ecuación FAS la sobreestima para creatininemias bajas. Para minimizar sus limitaciones, el European Kidney Function Consortium propuso la ecuación EKFC combinando características de diseño de FAS y CKD-EPI. Objetivo: evaluar el comportamiento de las ecuaciones EKFC vs. CKD-EPI y FAS en jóvenes, las diferencias en TFGe y la concordancia en asignación a categorías de TFG. Metodología: estudio analítico aprobado por el Comité Asesor de Ética y Seguridad de la Investigación de la Facultad de Bioquímica y Ciencias Biológicas de la UNL, con una muestra de 157 estudiantes voluntarios, de entre 18 y 37 años. Para la medición de la creatininemia se utilizó el método Jaffé cinético trazable a Isotopic Dilution Mass Spectroscopy, con el programa estadístico MedCalc. Resultados: EKFC: TFGe menores que CKD-EPI y FAS, total y por sexo. Media de las diferencias (mL/min/1,73 m2): (CKD-EPI - EKFC) totales = 10,42; 18-20 años = 11,91; 21-30 años = 11,10; 31-37 años = 8,96 / (FAS-EKFC) totales = 2,79; FAS ≤ 110 mL/min/1,73 m2 y mayor: 1,1 y 9,0 respectivamente. Asignación a categorías G: kappa menores EKFC vs. CKD-EPI que vs. FAS. Recategorización: 13,4 % en G1 por CKD-EPI categorizados G2 por EKFC; 0,6 % respecto a FAS en igual sentido. Asignación a categorías ≥ 75mL/min/1,73 m2 o menor: buena concordancia. Conclusiones: en la muestra, EKFC cumple los objetivos de su diseño. La sobreestimación de TFGe por CKD-EPI en adultos jóvenes disminuyó, más fuertemente hacia los 18 años, y corrigió la de FAS para creatininemias bajas. Es importante desarrollar estimadores de TFG basados en creatininemia que cubran todo el rango de edades y estados de función renal.

Introduction: GFR is a kidney function indicator. The estimation of the GFR (eGFR) is carried out by equations. Most of them are applicable with in an age range. Discrepancies between the values are found when crossing a limit of age. CKD-EPI overestimates GFR in young adults; FAS overestimates it for low creatininemias. To minimize these limitations, the European Kidney Function Consortium proposed the EKFC equation that combines design features of FAS and CKD-EPI. Objective: The performance of EKFC vs. CKD-EPI and FAS in young people was evaluated: differences in eGFR and agreement in the allocation to GFR categories were found. Methods: Analytical study approved by the Ethics Committee. Sample: 157 volunteer students, 18-37 years old. Creatininemia: kinetic Jaffé method traceable to Isotopic Dilution Mass Spectroscopy. Program: MedCalc. Results: EKFC: eGFR lower than CKD-EPI and FAS, total and by sex. Means of the differences (mL/min/1.73m2): total (CKD-EPI - EKFC) = 10.42; 18-20 years = 11.91; 21-30 years = 11.10; 31-37 years = 8.96 // (FAS-EKFC) total = 2.79; FAS≤ 110 mL/min/1.73m2 and higher: 1.1 and 9.0 respectively. Allocation to G categories: lower kappa EKFC vs. CKD-EPI than vs. FAS. Recategorization: 13.4% in G1 by CKD-EPI categorized G2 by EKFC; 0.6% compared to FAS, in the same sense. Allocation to categories ≥75mL/min/1.73 m2 or less: good agreement. Conclusions: In the sample, EKFC meets the objectives of its design. The overestimation of eGFR by CKD-EPI in young adults decreased, even more around 18 years of age, and corrected that of FAS for low creatininemias. It is important to develop GFR estimators based on creatininemia that cover the entire range of ages and renal function status.

Update and interpretation of the European LeukemiaNet guideline for the diagnosis and treatment of acute myeloid leukemia in 2022 / 白血病·淋巴瘤

The 2010 and 2017 editions of the European LeukemiaNet (ELN) guideline for the diagnosis and treatment of acute myeloid leukemia (AML) have been widely used in clinical practice. With further understanding of the molecular biological mechanisms of AML and tremendous progress in the application of clinically targeted drugs, the 2022 edition ELN AML guidelines were recently published online in the Blood. The article interprets the updated key points of the guideline.

Interpretation of International Evidence-based Guideline on Point-of-Care Ultrasound for Critically Ill Neonates and Children Issued by the European Society of Paediatric and Neonatal Intensive Care / 中国小儿急救医学

In 2020, the European Society of Paediatric and Neonatal Intensive Care first issued the international point-of-care ultrasound(POCUS) guideline for the critically ill newborns and children, which provided an evidence-based foundation to standardize the use of POCUS in the critically ill neonates and children.It has been widely recognized by neonatology and pediatric critical physicians worldwide.In order to keep our domestic colleagues updated and promote the POCUS application based on this international standard, the guideline was summarized and interpreted in this review.

Interpretation of the European Society for Vascular Surgery (ESVS) 2022 clinical practice guidelines on the management of chronic venous disease of the lower limbs: Iliac vein diseases / 中国胸心血管外科临床杂志

@#The European Society for Vascular Surgery (ESVS) 2022 clinical practice guidelines showed us venous thrombosis management in January 2022. In terms of iliac vein diseases, it retained some guiding views, upgraded some guiding views, and added some new views compared with the version 2015. It has good guidance and reference significance for medical staff and patients. The part of the guidelines about iliac vein disease is worth our interpretation.

A comparative study of regulations on botanicals registration in Australia and the European Union / 国际中医中药杂志

Australia and EU Member States have been the important components of global herbal medicine market. The legal use of Chinese Materia Medica in Australia and EU Member States is closely related to the internationalization of Chinese medicine, therefore it is of great significance to conduct a comparative study on their herbal medicine registration regulations. By summarizing the regulations issued by Therapeutic Goods Administration (TGA) and European Medicines Agency (EMA), and comparing related definitions and the regulations on quality management and medicinal product registration, we found that the method No.3 of L (A) 3 and the traditional-use registration are more conductive to bringing Chinese patent medicines to market in Australia and the EU Member States.

Analysis of simplified registration of traditional herbal medicinal products in European Union / 国际中医中药杂志

Europe occupies an important position in the world herbal medicine market. The registration of Traditional Chinese Medicine (TCM) in EU is of great significance to the internationalization of TCM. The European Medicines Agency (EMA) has designed a relatively complete management system and regulatory guidelines for the registration and supervision of herbal medicinal products. The promulgation of the DIRECTIVE 2004/24/EC (2004 / 24 / EC) indicates that TCM could enter the EU market through simplified registration. Based on the registration conditions, registration authority and document guideines of Traditional Herbal Medicinal Products (THMPs) in EU, this paper analyzes the application requirements of simple registration of traditional herbal products in EU, and provides suggestions for the simplified registration of TCM in EU according to the registration requirements of medicinal history, quality requirements and application data format.