ABSTRACT
Objective: To investigate the chemical constituents from the fruit of Euscaphis fukienensis. Methods: The chemical constituents were isolated and purified by silica gel, Sephadex LH-20 column chromatography and liquid phase preparation, and the structure were elucidated on the basis of nuclear magnetic technique. Results: Eighteen compounds were obtained from the fruit of E. fukienensis, which were named as betulinic acid (1), tetraketide (2), β-sitosterol (3), oleanolic acid (4), pomolic acid (5). β-amyrin (6), gallic acid (7), 3,3’-dimethoxy ellagic acid (8), quercetin (9), kaempferol (10), isorhamnetin (11), 2-epitormentic acid (12), 3,3’,4’-trimethoxy ellagic acid (13), 1-oxosiaresinolic acid (14), 2-oxopomolic acid (15), momordic acid (16), ursolic acid (17), isorhamnetin-3-O-rutinoside (18). Conclusion: Compounds 6, 11-15 and 18 are isolated from E. fukienensis for the first time, and compounds 13-15 are isolated from the genus Euscaphis for the first time.
ABSTRACT
Objective: To investigate the compouds from methylene dichloride and n-butyl alcohol parts of 70% ethanol extract of the fruits of Euscaphis fukienensis. Methods: The compounds were isolated and purified by Sephadex LH-20, silica gel column chromatographies, and recrystallization. Their structures were identified by physicochemical properties and spectroscopic methods. Results: Ten compounds were isolated and identified as 1, 2-benzenedicarboxylic acid (1), butanedioic acid (2), gallic acid (3), isorhamnetin-3-O-glucoside (4), 4-hydroxy-benzoic acid (5), 2-methyl-5, 7-dihydroxychrom one (6), muconic acid (7), quercetin-3-O- glycosidase (8), β-sitosterol (9), and daucostrol (10). Conclusion: Compounds 1-7 are isolated from the fruits of E. fukienensis for the first time.