ABSTRACT
Abstract Introduction: Posttraumatic stress disorder (PTSD) is a highly prevalent disorder with important social consequences. Several models have been developed with the aim of understanding the mechanisms underlying its symptoms. Intrusions are idiosyncratic symptoms that commonly take the form of involuntary recollection of images or flashbacks about the traumatic event. Objective: To review how memory is conceptualized in each of these models and the implications for clinical practice. Methods: A narrative review of the literature was conducted through analysis of the perspectives of memory in theoretical models of PTSD. Results: Two main perspectives were identified: 1) models in which specific mechanisms of memory for processing traumatic events are proposed, especially those based on clinical studies, and 2) models in which common mnemonic mechanisms are utilized to explain the phenomenon, primarily based on basic experimental research studies investigating memory. The different theories based on these approaches have led to distinct psychotherapy interventions. Conclusion: In order to clarify these discrepancies, future research should aim for the methodological rigor of experimental studies, while maintaining the ecological applicability of findings. Cognitive experimental psychopathology is therefore an area on which research funding should be focused. Such studies could elucidate the role of mnemonic aspects in PTSD and how they impact psychological treatments.
Resumo Introdução: O transtorno de estresse pós-traumático (TEPT) é altamente prevalente e traz consequências sociais importantes. Diversos modelos foram desenvolvidos com o objetivo de compreender os mecanismos subjacentes aos seus sintomas. Intrusões constituem sintomas idiossincráticos, que regularmente tomam a forma de lembranças involuntárias de imagens ou flashbacks do evento traumático. Objetivo: Revisar como a memória é definida conceitualmente nos modelos teóricos propostos e as implicações para a prática clínica. Métodos: Uma revisão narrativa da literatura foi conduzida através da análise das perspectivas de memória em modelos teóricos de TEPT. Resultados: Duas perspectivas principais foram identificadas: 1) modelos com a proposição de mecanismos de memória específicos ao processamento de eventos traumáticos, especialmente apoiados em estudos clínicos, e 2) modelos em que mecanismos mnemônicos comuns são utilizados para explicar o fenômeno, primariamente baseados em estudos experimentais de base investigando memória. As diferentes teorias baseadas nessas perspectivas levaram a distintas abordagens psicoterapêuticas. Conclusões: Para clarificar essas discrepâncias, sugere-se que pesquisas futuras busquem maior rigor metodológico de estudos experimentais, mantendo a aplicabilidade ecológica dos achados. A psicopatologia cognitiva experimental é uma área na qual devem ser focados os financiamentos de pesquisa. Tais estudos podem elucidar o papel de aspectos mnemônicos no TEPT e como impactam tratamentos psicológicos.
Subject(s)
Humans , Stress Disorders, Post-Traumatic/psychology , Stress Disorders, Post-Traumatic/therapy , Memory , Psychotherapy/methods , Models, PsychologicalABSTRACT
La investigación con animales no humanos como sujetos experimentales, para entender el comportamiento humano, se basa en la noción darwiniana de la continuidad de las especies. En este marco encontramos modelos análogos para entender la biología y el comportamiento humanos en especies no humanas. En psicología, los modelos animales han probado ser una herramienta efectiva para el entendimiento del comportamiento humano, tanto normal como anormal. En la presente revisión discutimos cómo los modelos animales han sido usados al investigar la psicopatología. Luego de revisar tres modelos animales históricos de psicopatologías específicas, discutimos cómo los fenómenos descubiertos al estudiar el condicionamiento pavloviano han contribuido a nuestra comprensión de la etiología y mantención de la psicopatología humana, cómo la tradición pavloviana ha contribuido al desarrollo de mejores formas de tratamiento para desórdenes del comportamiento, y de forma más general, cómo los fenómenos pavlovianos se encuentran implicados en casi todas las interacciones entre un organismo y su ambiente.
Research using non-human animals as experimental subjects to understand human behavior have been based on the Darwinian notion of continuity between species. In this framework, we find analogous models to understand human biology and behavior in nonhuman species. In the scientific study of psychology, animal models have proven to be an effective tool for understanding both normal and abnormal human behaviors. In the present review, we discuss how animal models have been used in investigating psychopathology. After reviewing three historical animal models of specific psychopathologies, we discuss how phenomena discovered while studying Pavlovian conditioning have contributed to our understanding of the etiology and maintenance of human psychopathology, how the Pavlovian tradition has contributed to the development of better ways to treat these behavioral disorders, and more generally, how Pavlovian phenomena are implicated in almost all interactions between an organism and its environment.