ABSTRACT
China produces about 15 000 tons of expired drugs every year. Standardized destruction of expired drugs consumes a large number of secondary costs， causing huge economic losses. Improper handling will also lead to serious environmental pollution， endanger national health and even endanger public safety. This paper analyzes the hazards， sources and disposal methods， and research status of expired drugs， introduces the Shelf-Life Extension Program of United States， and put forward feasible measures for the recovery， integration and reuse of expired drugs. It is suggested to construct a scientific and reasonable recovery and disposal system of expired drugs in combination with the actual situation in China， explore the strategy of extending the expiration of drugs， and greatly reduce the waste of drug resources.
ABSTRACT
Pharmaceutical waste can result from many locations and from many activities in health care facilities. They generate medicines waste which are compounding from pharmacy. In the present study, an attempt has been made to know the effect of Ranozex expired tablet on soil physical quality. The expired tablets were applied at a concentration of 150 mg, 250 mg, 500 mg, 750 mg and 1g. The expired ranozex tablets was mixed with sandy loam clay soil and kept for observation for 7 to 27 days respectively. The experimental setup was maintained till 27 days, at every 7 days intervals, the soil was extracted and subjected to selected physical properties such as bulk density, particle density, water holding capacity and moisture content. From the results, it was found that, the bulk density and particle density were found to be reduced. The percentage of water holding capacity was found to be higher during the experimental period