ABSTRACT
Objective@#To investigate the quality of life(QoL) and emotion symptoms(anxiety symptom and depressive symptom), and its influencing factors in patients with permanent peripheral facial paralysis(PPFP).@*Methods@#A case-control trial was conducted to evaluate the QoL status and emotion symptoms of 79 PPFP patients(PPFP group, disease course >12 months) between January 2017 and January 2018 from the Affiliated Hospital of Yangzhou University, and 42 healthy individuals were selected as control group.The generic questionnaire medical outcomes study short-form 36 items health survey(SF-36), Chinese version of facial clinimetric evaluation(FaCE) scale, self-rating depression scale(SDS) and self-rating anxiety scale(SAS) were evaluated.The correlation among SF-36, SDS, SAS and FaCE was evaluated.SPSS 21.0 software was used to analyze the data.@*Results@#By the assessment of SF-36, the score of vitality[(73.23±15.04)points], social function[(72.41±15.46)points], role-emotion[(72.53±15.27)points] and mental health[(73.35±14.54)points] in four dimensions of the PPFP group were lower than those of the control group [(97.56±3.76)points, (96.51±3.32)points, (97.09±2.49)points and (96.63±2.37)points](t=-10.506, -10.144, -10.505, -10.403, all P<0.001), but the scores of physical function, role-physica, bodily pain and general health in four domains of the PPFP group were similar with those of the control group (all P>0.05). By the assessment of FaCE, the total score of the PPFP group was lower than those of the control group [(48.63±17.44)points vs.(100.00±0.00)points, t=-19.281, P<0.05]. The score of SDS in the PPFP group was higher than those of the control group[(48.43±11.57)points vs.(40.63±5.39)points](t=4.174, P<0.001), but the score of SAS had no statistically significant difference between the two groups (P>0.05). According to the assessment of the correlation among SF-36, SDS, SAS and FaCE, the total scores of FaCE in the PPFP group was related only to SF-36 related mental health dimensions and SDS(r=-0.848~0.908, all P<0.001). Multiple linear regression analysis showed that marital status(t=-2.442, P=0.017), occupation(t=-2.377, P=0.020), and age(t=-5.501, P=0.000) were negatively correlated with the SDS scores; with/without synkinesis(t=3.604, P= 0.042), disease course(t=4.152, P=0.000), and the level of House-Brackmann grading system(HBGS)(t=2.116, P=0.038) were positively associated with the SDS of the PPFP group.However, disease course (t=-2.616, P=0.011), HBGS(t=-6.523, P=0.000) were negatively correlated with the total scores of FaCE, and with/without synkinesis(t= 2.767, P=0.000) was positively associated with the total scores of FaCE.@*Conclusion@#The patients with PFPP have a poorer quality of life and experienced greater psychological distress than healthy individuals.The present study suggested that age, gender, occupation, marital status, disease course, with/without synkinesis, the sources of PPFP and the level of HBGS are associated with depression increasing and quality of life decreasing in PPFP patients.
ABSTRACT
To investigate the quality of life (QoL) and emotion symptoms (anxiety symptom and depressive symptom), and its influencing factors in patients with permanent peripheral facial paralysis ( PPFP). Methods A case-control trial was conducted to evaluate the QoL status and emotion symptoms of 79 PPFP patients (PPFP group,disease course ＞12 months) between January 2017 and January 2018 from the Affiliated Hospital of Yangzhou University,and 42 healthy individuals were selected as control group.The generic questionnaire medical outcomes study short -form 36 items health survey(SF-36),Chinese version of facial clinimetric evaluation (FaCE) scale,self-rating depression scale(SDS) and self-rating anxiety scale (SAS) were evaluated.The correlation among SF-36,SDS,SAS and FaCE was evaluated.SPSS 21.0 software was used to analyze the data.Results By the assessment of SF-36,the score of vitality[(73.23 ±15.04)points],social function[(72.41 ±15.46)points],role-emotion[(72.53 ±15.27) points] and mental health [(73.35 ±14.54) points] in four dimensions of the PPFP group were lower than those of the control group [( 97.56 ±3.76 ) points, (96.51 ±3.32 ) points, (97.09 ± 2.49)points and (96.63 ±2.37) points] (t＝-10.506,-10.144,-10.505,-10.403,all P＜0.001),but the scores of physical function ,role-physica,bodily pain and general health in four domains of the PPFP group were similar with those of the control group (all P＞0.05).By the assessment of FaCE,the total score of the PPFP group was lower than those of the control group [(48.63 ±17.44) points vs.(100.00 ±0.00) points,t＝-19.281,P＜0.05].The score of SDS in the PPFP group was higher than those of the control group [(48.43 ±11.57)points vs. (40.63 ±5.39) points] ( t ＝4.174, P ＜0.001), but the score of SAS had no statistically significant difference between the two groups (P＞0.05).According to the assessment of the correlation among SF -36,SDS,SAS and FaCE,the total scores of FaCE in the PPFP group was related only to SF -36 related mental health dimensions and SDS(r＝-0.848 ～0.908, all P ＜0.001).Multiple linear regression analysis showed that marital status ( t ＝-2.442,P＝0.017),occupation ( t＝-2.377,P＝0.020),and age ( t ＝-5.501,P＝0.000) were negatively correlated with the SDS scores;with／without synkinesis ( t ＝3.604, P ＝0.042), disease course ( t ＝4.152,P ＝0.000),and the level of House-Brackmann grading system(HBGS)(t＝2.116,P＝0.038) were positively associated with the SDS of the PPFP group.However,disease course (t＝-2.616,P＝0.011),HBGS(t＝-6.523,P＝0.000) were negatively correlated with the total scores of FaCE ,and with／without synkinesis (t＝2.767,P＝0.000) was positively associated with the total scores of FaCE.Conclusion The patients with PFPP have a poorer quality of life and experienced greater psychological distress than healthy individuals .The present study suggested that age ,gender, occupation,marital status,disease course,with／without synkinesis ,the sources of PPFP and the level of HBGS are associated with depression increasing and quality of life decreasing in PPFP patients.