A Case of Facial Lichen Striatus Improved with Topical Tacrolimus / 대한피부과학회지

A 31-year-old woman presented with 2 year history of multiple, pinhead-sized erythematous papules, which had become coalescent in linear arrangement from the forehead to the left nasal ala. Histopathologically, the lesion showed hyperkeratosis, spongiosis and inflammatory cell infiltration around the skin appendages, and was therefore diagnosed as facial lichen striatus. The patient had been treated with an intermittent topical steroid application for about two years, but this had not been effective. However, application of 0.03% tacrolimus ointment showed dramatic improvement.

A Case of Milia Occurring on Lichen Striatus of the Face / 대한피부과학회지

A healthy 4-year-old boy presented with a linear erythematous eruption, along with some pearly papules on the right cheek. The distribution of the lesions corresponded to that of Blaschko?s lines. Histopathological examination showed necrotic keratinocytes and vacuolar changes on the basal layer in the epidermis, and a superficial and deep perivascular, perieccrine, and perifollicular lymphocytic infiltrate in the dermis. In addition, a small keratin-filled cyst was observed in the upper dermis. These findings were consistent with a diagnosis of milium developing on lichen striatus. We applied 0.03% topical tacrolimus ointment twice daily. On follow-up 12 months later, the linear erythematous eruption cleared, but the pearly papules persisted.