ABSTRACT
Cryotherapy has been shown to be an effective treatment for retinopathy of prematurity (ROP) stage 3+. However, the outcome of cryotherapy is less favorable in zone 1 ROP than in zone 2 ROP. We suspected whether there may be differences in the outcomes of cryotherapy if the zone of ROP is further divided. So we reviewed the records of 85 premature infants (145 eyes) who had undergone cryotherapy for ROP. The frequencies of favorable outcome were 42.9% of 14 eyes (zone 1), 78.9% of 38 eyes (posterior zone 2), 92.9% of 70 eyes (mid zone 2), and 100.0% of 23 eyes (anterior zone 2), respectively (p < 0.001). These results suggest that the more posteriorly the ROP is located, the less favorable the outcome of cryotherapy.
Subject(s)
Humans , Infant , Infant, Newborn , Cryotherapy/methods , Follow-Up Studies , Postoperative Complications , Retinopathy of Prematurity/pathology , Retrospective Studies , Treatment OutcomeABSTRACT
We diagnosed 48 babies as retinopathy of prematurity (ROP) among 438 premature infants from April 1995 to March 1996 in Gil General Hospital. Among 48 ROP babies, 16 (30 eyes) infants progressed to stage 3+ ROP. Mean birth weight was 1474.0 gm, mean gestational age was 29.7 weeks and mean oxygen inhalation duration was 471.2 hours. Among 30 eyes of stage 3+ ROP, 25 eyes progressed to threshold stage and 5 eyes regressed spontaneously. Ten eyes were treated with cryotherapy and 15 eyes with diode laser photocoagulation and the treatment depends on random selection. Four eyes progressed to stage 5 ROP in spite of photocoagulation and encircling scleral buckling. Favorable outcome was achieved in all eyes treated with cryotherapy, and in 73. 3% of eyes laser-treated.
Subject(s)
Humans , Infant , Infant, Newborn , Birth Weight , Cryotherapy , Gestational Age , Hospitals, General , Infant, Premature , Inhalation , Lasers, Semiconductor , Light Coagulation , Oxygen , Retinopathy of Prematurity , Scleral BucklingABSTRACT
Cryotherapy or photocoagulation is indicated for threshcld stage 3+ retinopathy of prematurity. Twenty-three infants with threshold stage 3+ retinopathy of prematurity were treated with cryotherapy and were analyzed from June 1988 10 December 1991. In patient with cryotherapy, mean gestational age was 30.0 weeks, mean birth weight was 1281gm, and mean number of cryoapplications was 45.4. 32 of 44 eyes (72.7%) had favorable outcomes, and 12 of 44 eyes (27.3%) had unfavorable outcomes.