ABSTRACT
PURPOSE: To evaluate the effects of occlusion therapy on anisometropic amblyopia and investigate the factors that influence on the final vision. METHODS: Fifty two patients with anisometropic amblyopia, whose age ranged from 3 to 12 years, were treated with full and partial occlusion therapy. RESULTS: The degree of anisometropia was 3.23+/-1.99 D in hyperopia group and 2.00+/-0.98 D in myopia group. The best corrected visual acuity and final vision were 0.29+/-0.14 and 0.52+/-0.22 in hyperopia group, while 0.34+/-0.16 and 0.63+/-0.16 in myopia group. But statistically significant difference was not found between two groups. The best corrected visual acuity was significantly correlated with the degree of anisometropia. The final vision was also significantly correlated with the degree of anisometropia. As expected, the final visual acuity was strongly correlated with the best corrected visual acuity. But no statistically differences were found based on the age of initial treatment and sexual difference. CONCLUSIONS: The severity of amblyopia and the effect of occlusion therapy were more correlated with the degree of anisometropia than the age of initial treatment and the type of anisometropia.