Treatment of Verrucae with Flashlamp-pumped Pulsed Dye Laser

BACKGROUND: Warts are common virus-induced lesions that are troublesome to treat, especially in children. Recently, some trials have suggested that the pulsed dye laser may also be useful for the treatment of warts. OBJECTIVE: To determine the effectiveness and safety of 585nm flashlamp-pumped pulsed dye laser treatment of warts. METHODS: Fifty patients representing a total of 265 warts were recruited for the study. Patients were treated using the flashlamp-pumped pulsed dye laser with a pulse duration of 450 sec, a spot size of 5mm, and energy fluence ranging between 7 to 9 J/cm2. Patients in whom no visible evidence of warts remained before 5 treatment sessions were classified as 'cured'. RESULTS: The cure rates were 89% for hand warts, 21% for plantar warts, 58% for periungual or subungual warts, 98% for limb warts and 100% for facial warts. Significant difference in the clearance rate of warts was found according to the maximum diameter of warts (≤0.3cm, >0.3cm) (<0.05). CONCLUSION: The 585nm flashlamp-pumped pulsed dye laser had potential effectiveness for the treatment of small warts on the hands, face, and limbs, but it is less effective for plan-tar warts, or larger warts.

Reflectance Spectrophotometry for the Evaluation of Therapeutic Effect of Falshlamp - pumped Pulsed Dye Laser for Nevus Flammeus / 대한피부과학회지

BACKGROUND: At present, flashlamp-pumped pulsed dye lasers are treatment of choice for the treatment of congenital capillary malformations like nevus flammeus. Clinical methods have been generally used to evaluate their effectiveness in many papers. OBJECTIVE: To evaluate the effectiveness of the laser therapy in nevus flammeus patients, we used reflectance spectrophotometry as a supportive objective method in addition to the clinical evaluation. METHODS: Thirty-two patients with definite nevus flammeus skin lesion, mainly on head and neck, were treated with flashlamp-pumped pulsed dye laser(SPTL-1b) at 8 week interval. Patients without previous treatment and the others with previous treatments were grouped separately to compare the influence of previous treatment to laser therapy. Erythema/Melanin indices were measured before and after laser therapy in both normal and lesional skin. Based on these indices, relative blanching effect were calculated. RESULTS: Clinically, they showed 58.6% improvement in their skin color in average and Erythema/Melanin indices measured on normal skins were 13.09+/-3.91 a.u. and 34.65+/-2.82 a.u.. Erythema indices measured on lesional skins were 26.07+/-10.26 a.u. and 20.73+/-8.81 a.u. in non-treated group and 2453+/-6.14 a.u. and 21.18+/-5.47 a.u. in pre-treated group, alternatively. Relative blanching effect in both groups were calculated as 35.9% and 31.6%, meaning no significant difference(p>0.3). Clinical evaluation and relative blanching effect showed good correlation(r=0. 691). CONCLUSION: Reflectance spectrophotometry can be useful in evaluating successful laser treatments in nevus flammeus patients. Reflectance measurements, an objective estimate of blanching, correlate well with the clinical results, and are helpful in monitoring and predicting the therapeutic outcome in dye laser treated patients.

A Study of the Therapeutic Effect of Rosacea by the Flashlamp - Pumped Pulsed Dye Laser ( SPTL - 1 ) / 대한피부과학회지

BACKGROUND: Persistent facial elangiectssia, erythema, and flushing are the major cosmetic problems in patients with rosacea, However various therapeutic modalities for roacea papules and pustules, including topical antibiotics, systemic antibiotics, isotretinoin, and systernic and topical metronidazole, are not effective in reducing telangiectasia and flushing reactions present inrosacea patients. The flashlamp-pumped pulsed dye laser has been deacribed as a succqssful treatment for port wine stains with telangiectasia as part of their abnomalities. A clinical study was therefore undertaken in a group of rosacea patients, who recieves this laser to areas of facial taieous lesions. OBJECTIVE: The purpose of the study was to evaluate the therapeutic effect of the flashlamp-pumped pulsed dye laser(SPTL-1) for osacea, especially telangiectasia and flusing reactions. METHODS: Forty-eight. patient with rosacea were studied to evaluatic the therapeutic effects of the SPTL-1 flashlamp-pumped pulsed dye laser (Candela corp.Wayland Mass.) at the Department of Dermatology in Dong-A University Hospital for 20 months from Januarg 1991 to August 1992. RESULTS: 1. Total therapeutic effects of this SPTL-1 laser showed excellent re:ults in 22.9%, good in 62.5%, fair in 8.3%, and poor in 6.3%. 2. Therapeutic effects of rosacea-associated lesions showed exeellerit or good results in 85.4% of patient,s with erythema and telangiectasia, 84% patients with papules, 100% patients with pustules, and 93.7% of patients with facial flushing. 3. Complications included trarsient hyperpigmentation (14.6%), section lary bacterial infection(6.3%), hypopigmentation(2.1%), and atropic scar(2.1%). 4. The recurrence rat.e was 2,9,%. CONCLUSION: The flashlamp-pumped pulsed dye laser (SPTL-1) is a dry effective mode of treatment for rosacea, including persistent telangiectasia and facial flushing ri.actions which were intractable to previous other therapeutic modalities.

A Study of the Therapeutic Effect of Rosacea by the Flashlamp - Pumped Pulsed Dye Laser ( SPTL - 1 ) / 대한피부과학회지

BACKGROUND: Persistent facial elangiectssia, erythema, and flushing are the major cosmetic problems in patients with rosacea, However various therapeutic modalities for roacea papules and pustules, including topical antibiotics, systemic antibiotics, isotretinoin, and systernic and topical metronidazole, are not effective in reducing telangiectasia and flushing reactions present inrosacea patients. The flashlamp-pumped pulsed dye laser has been deacribed as a succqssful treatment for port wine stains with telangiectasia as part of their abnomalities. A clinical study was therefore undertaken in a group of rosacea patients, who recieves this laser to areas of facial taieous lesions. OBJECTIVE: The purpose of the study was to evaluate the therapeutic effect of the flashlamp-pumped pulsed dye laser(SPTL-1) for osacea, especially telangiectasia and flusing reactions. METHODS: Forty-eight. patient with rosacea were studied to evaluatic the therapeutic effects of the SPTL-1 flashlamp-pumped pulsed dye laser (Candela corp.Wayland Mass.) at the Department of Dermatology in Dong-A University Hospital for 20 months from Januarg 1991 to August 1992. RESULTS: 1. Total therapeutic effects of this SPTL-1 laser showed excellent re:ults in 22.9%, good in 62.5%, fair in 8.3%, and poor in 6.3%. 2. Therapeutic effects of rosacea-associated lesions showed exeellerit or good results in 85.4% of patient,s with erythema and telangiectasia, 84% patients with papules, 100% patients with pustules, and 93.7% of patients with facial flushing. 3. Complications included trarsient hyperpigmentation (14.6%), section lary bacterial infection(6.3%), hypopigmentation(2.1%), and atropic scar(2.1%). 4. The recurrence rat.e was 2,9,%. CONCLUSION: The flashlamp-pumped pulsed dye laser (SPTL-1) is a dry effective mode of treatment for rosacea, including persistent telangiectasia and facial flushing ri.actions which were intractable to previous other therapeutic modalities.