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Arq. neuropsiquiatr ; 68(4): 506-510, Aug. 2010. graf, tab
Article in English | LILACS | ID: lil-555226

ABSTRACT

This study had the objective to verify if the presence of wearing-off phenomenon in patients with Parkinson's disease (PD) could be better identified by the administration of the "Wearing-off Questionnaire Card" (QC). The participant patients were first evaluated by resident doctors in neurology and then invited to answer the QC for detection of motor and nonmotor wearing-off manifestations. Seventy and nine patients were enclosed in the study. The questionnaire revealed that 63 patients (80 percent) presented wearing-off, whereas the consultation by the resident doctors only identified 33 subjects (41 percent) with this phenomenon. The motor wearing-off manifestations were more frequent then the nonmotor. We conclude that the administration of the QC in patients with PD may be a useful tool for the diagnosis of wearing-off phenomena.


Este estudo teve como objetivo verificar se a presença do fenômeno wearing-off em pacientes com doença de Parkinson pode ser melhor identificada pela aplicação do cartão questionário wearing-off (QC). Os pacientes participantes foram avaliados pelos médicos residentes em neurologia e depois foram convidados a responder as questões do QC para detecção das manifestações motoras e não motoras do wearing-off. O número de pacientes estudados foi de 79. O questionário revelou que 63 pacientes (80 por cento) apresentaram wearing-off, enquanto que a consulta dos residentes identificou apenas 33 indivíduos (41 por cento) com este fenômeno. As manifestações motoras foram mais freqüentes do que as não motoras. Nós concluímos que a aplicação do QC em pacientes com doença de Parkinson pode ser uma ferramenta útil para o diagnostico do fenômeno wearing-off.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Antiparkinson Agents/adverse effects , Drug Tolerance , Levodopa/adverse effects , Parkinson Disease/drug therapy , Antiparkinson Agents/therapeutic use , Levodopa/therapeutic use , Sensitivity and Specificity , Severity of Illness Index , Surveys and Questionnaires
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