Regulatory status of bioactive non-nutritional food components in Southeast Asian countries

@#A review conducted on the regulatory status of bioactive non-nutritional food components in foods and beverages in eight Southeast Asian countries indicates these components have been recognised for their health benefits. Indonesia and Malaysia have promulgated specific regulations allowing the addition of these bioactive components in foods and beverages, provided a list of the permitted components that may be used, and clear process for the industry to apply for new components. Both countries also have separate regulations that govern the making of function claims which refer to the beneficial physiological or health effects brought about by such bioactive components. The other six countries do not have a specific regulation governing the use of these bioactive components. However, these countries also permit the making of similar function claims, provided they are scientifically substantiated, preferably human clinical trials. Each country has slightly different requirements and process in place for reviewing applications for claims. All countries, except Myanmar, also allow the sale and marketing of foods containing probiotics, another functional food component. Indonesia, Malaysia, Philippines and Thailand have promulgated specific probiotic regulations and, except for Indonesia, have published permitted list of probiotics. All seven countries have provisions for the industry to apply for the use of new probiotics. Malaysia, Philippines, Singapore and Thailand permit the use of a pre-approved generic function claims related to probiotics. The sharing of experiences in regulatory approaches would be beneficial to the advancement of scientific and regulatory development of bioactive non-nutritional food components in the region and would benefit all stakeholders.

The health benefits of the active ingredients and whole food components of natural plants through regulating the flora / 生物工程学报

With the cooperation of bacteria and the human body, the nutrients in food are deeply digested, utilized, and shared. In addition, symbiosis is formed between microorganisms and hosts. Such a delicate combination makes the microorganisms form the inherent flora in the human body. They obtain the biological basis for survival, and provide the necessary regulation and support for the host in terms of immunity and nutrition, through their functional metabolism and population signals. At present, most of the researches focus on the isolation and evaluation of the functional components of plants, such as plant polysaccharides, polyphenols, flavonoids, and other active functional components. However, in traditional Chinese medicine, plants are often used with whole food components. To date, studies have found that the dynamics of flora affecting human health are not fixed, nor dependent on the change of a single strain. The ecological competition and metabolic regulation between microorganisms are usually coevolved with the host. The regulatory effect of natural plants for both medicine and food mainly depends on their whole food components. This provides evidence to support the role of whole food components played in promoting the efficacy of traditional Chinese medicine from the perspective of microenvironment. Therefore, the development and utilization of medicinal and edible natural plant activities should be fully understood and evaluated with flora regulation.

Food Intake and Thermogenesis in Adipose Tissue

Brown adipose tissue (BAT) is regarded as a key target for developing interventions to prevent and treat obesity and age-related diseases. In addition, uncoupling pro tein 1 (UCP1)

Association of HbA1c level with nutritional status in community-based patients with type 2 diabetes / 中华内分泌代谢杂志

Objective To explore the possible correlation between HbA1c level and nutritional status in community.based patients with type 2 diabetes.Methods A totaI of 219 type 2 diabetes patients were assigned into 2 groups:one with HbAIc<6.5%(n:108)and HbA1f≥6.5%(n=111).Metabolic parameters,food components.and nutritional status were compared between 2 groups.Results (1)49.32% of the participants attained HbA1c<6.5%.(2)HbA1c level was positively correlated with fasting plasma glucose,postprandial plasma glucose,and homeostasis assessment for insulin resistance(HOMA-IR)(r were 0.56,0.49,and 0.20,respectively,P<0.05 or P<0.01),but negatively correlated with high-density lipoprotein-cholesterol(HDL-C)(r=0.16,P<0.05).(3)Linear regression analysis showed that energy,carbohydrate,protein,and fat were the independent risk factors of HbA1c(all P<0.05).(4)Patients with HbA1c<6.5%consumed more fruits.The intake of pure energy-providing foods and protein-,fat-,or saturated fatty acid-rich foods were more frequent in patients with HbA1c≥6.5%(P<0.05).(5)The linear regression revealed that HbA1c level were decreased 0.36%(P<0.10)or 0.46%(P<0.01)by intake of more fruits,roughage and beans,and HbA1c levels were also decreased 0.42%(P<0.05)or 0.37%(P<0.10)by intake of less meat or oils.Conclusions In communitybased patients with type 2 diabetes mellitus,the incidence of HbA1c<6.5% remains low,There exists great difference in nutritional status between the groups with high and low HbA1c levels.The impact of diet OB HbA1c level is great.It's necessary to emphasize the importance of diet therapy far better diabetes control.

Comparison of food and life style between obese and non-obese groups / 中华内分泌代谢杂志

The relation of obesity with food components, genetic factors and life style were explored in obesity group (212 cases) and normal group (212 subjects). The result revealed close relationships among food components, life style or genetic factors and obesity. The food components and life style consisted of high fat and sugar, high salt diet, drinking, smoking and sedentary work. Parents with obesity conferred another factor.