ABSTRACT
Wumei Pill is a classic insect repellent prescription, which is used for ascaris lumbricoides and diarrhea. It is considered to be a representative prescription for the treatment of simultaneous occurrence of cold and heat syndromes. Its prescription is mainly composed of sour drugs ( Mume Fructus and bitter wine) and pungent drugs ( Aconiti Lateralis Radix Praeparataaconite, Cinnamomi Ramulus, Sichuan pepper, Angelicae Sinensis Radix, Zingiberis Rhizoma, and Asari Radix et Rhizoma), supplemented by bitter drugs ( Coptidis Rhizoma and Phellodendri Chinensis Cortex) and sweet drugs ( Ginseng Radix et Rhizoma and honey). From the point of view of "Tang-Ye-Jing-Fa Map", the role of liver is to disperse, whose deficiency leads to limb syncope, and excess leads to the full of hypochondrium and abdominal pain. The pungent herbs can tonify the liver-deficiency, the sour herbs can dispel the liver-excess, and sweet herbs can relive them both. The role of spleen is to moderate, whose deficiency leads to fatigue and weakness, and excess leads to the vomiting and diarrhea. The sweet herbs can tonify the spleen-deficiency, the pungent herbs can dispel the spleen-excess, and bitter herbs can relive them both. Therefore, the function of Wumei Pills is located in the liver and spleen, giving consideration to the heart and lung. It is used for the deficiency and excess mixed syndrome of liver and spleen, which is mainly characterized by chest and flank abdominal pain, limb chills, diarrhea, muscle and pulse contracture and the symptoms of the parts along the liver meridian. It is commonly used in the treatment of ascaris, diarrhea, impotence, depression. At the same time, it can also be used for the treatment of diseases about heart and lung, and cough, anxiety and other diseases.
ABSTRACT
Objective To provide references for the clinical application of Dunhuang prescriptions for treating internal medicine diseases by analyzing medication rules of Dunhuang manuscriptsFu Xing Jue based on data mining method.Methods TCM prescriptions for internal medicine diseases in the Dunhuang manuscriptsFu Xing Jue were input computer. Excel 2003 software was used to establish relevant database. Data mining method was used to analyze the medication rules.Results There were 61 TCM prescriptions in the Dunhuang manuscriptsFu Xing Jue, including66 kinds of Chinese herbal medicine and 336 times of total frequency of usage. The used core single herbs were as follows: Glycyrrhizae Radix et Rhizoma, Paeoniae Radix Alba, Zingiberis Rhizoma,Zingiberis Rhizoma Recens, Scuteliariae Radix, Inulae Flos, Ginseng Radix et Rhizoma, Jujubae Fructus, Lophatheri Herba, Schisandrae Chinensis Fructus, and Cinnamomi Ramulus; medicine types were tonifying-deficiency medicine, heat-clearing medicine, relieving exterior syndrome medicine, interior-warming medicine and antitussive and antiasthmatic medicine, with the cumulative frequency of 80.66%; medicine flavors were bitterness, sweetness and pungentness, with the cumulative frequency of 83.91%; medicine properties were coldness, warmness and peace, with the cumulative frequency of 87.95%; channel tropisms were stomach, lung, spleen, heart, kidney and liver, with the cumulative frequency of 86.15%. Clinical compatibility of medicines for treating internal medicine diseases in Dunhuang medical prescriptions were mainly qi-tonifying medicines (Glycyrrhizae Radix et Rhizoma, Ginseng Radix et Rhizoma and Jujubae Fructus), blood-replenishing medicine (Paeoniae Radix Alba), and nourishing medicines (Ophiopogonis Radix), supplemented by heat-clearing medicine (Lophatheri Herba andScuteliariae Radix),with relieving exterior syndrome medicines (Zingiberis Rhizoma Recens andCinnamomi Ramulus),interior-warming medicine (Zingiberis Rhizoma), antitussive and antiasthmatic medicine (Inulae Flos), inducing astringency medicine (Schisandrae Chinensis Fructus) as characteristic medication. High-frequency medicines constitute Dunhuang medical prescription of Xiaoyindan Decoction, which can be used to treat epidemic. Conclusion This article concluded the compatibility rules of Dunhuang manuscripts Fu Xing Jue, provide references for clinical medication and research and development of new medicine.