1.
Chinese Journal of Current Advances in General Surgery
;
(4)2004.
Article
in Chinese
| WPRIM
| ID: wpr-545475
ABSTRACT
Objective:To study the expression of Survivin and p27~(kipl)and their relationship with the clinical features of gallbladder cancer.Methods:Fifty specimens of gallbladder cancer,20 specimens of chronic cholecystitis,20 specimens of polypoid lesions of gallbladder(PLG)were included,the expression of Survivin and p27~(kipl)were detected using immunohistochemistry assay.Results:In 50 cases of gallbladder cancer,39 cases expressed Survivin and 22 cases expressed p27~(kipl).There was a negative correlation between the expression of p27 and survivin(P0.05),but the expression of p27~(kipl)was related to the pathological grade,clinical stage and lymph node metastasis of gallbladder cancer(P