ABSTRACT
Suryaprabha gulika is a Kharaleeya preparation mentioned in the Gulika prakarana of Sahasrayogam indicated for Sula, Swasa, Kasa and Mahajwara. It contains eleven ingredients namely Suddha Parada, Suddha Gandhaka, Suddha Hingu, Amalaki, Harithaki, Vibheethaki, Sunti, Pippali, Maricha, Yavani and Suddha Vatsanabha triturated for 6 hours in Jambeera swarasa. In this paper, the work done on pharmaceutical and analytical aspects of Suryaprabha gulika is detailed. Pharmaceutical study included Sodhana of Parada, Sodhana of Gandhaka, preparation of Kajjali, Sodhana of Hingu, Sodhana of Vatsanabha and the preparation of final product whereas the analytical study included evaluation of organoleptic characters, physico chemical parameters and analysis based on modern instrumentation techniques such as X-ray Fluorescence (XRF), X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM) and particle size analysis.
ABSTRACT
Introduction: Age-related macular degeneration (AMD) is a neurodegenerative disease which is one of the leading causes of vision loss affecting population above the age of 50 years. Of the two types wet and dry AMD, dry AMD constitute 90% of cases. Currently there is no effective treatment for AMD except for antioxidant supplementation which can delay the progression of AMD and its associated vision loss. In Ayurveda, it is a Vata Pitthadhika Drishtigata Roga compounded by Dhatukshaya in Vardhakya. The treatment should be Brimhana, Chakshushya and Rasayana to tackle the degenerative changes. Gandhaka Kalpa from Rasaratnasamucchaya and Ksheerabala 101 Avarti Taila has these properties to ameliorate the disease pathology. Hence a clinical study was planned with the objective to assess the effect of Gandhakakalpa internally and Ksheerabala 101 Avarti Taila Nasya in dry AMD. Methods: The study design was interventional, pre and post evaluation without control. After preparatory phase, patients were given Nasya with Ksheerabala 101 Avarti Taila followed by administration of Gandhaka Kalpa with concurrent administration of Ksheerabala 101 Avarti Taila as Pratimarsa Nasya. Study and follow up were done in 30 eyes. Results were documented and statistically analysed using Friedmains’s test, paired t test, Wilcoxon’s signed rank test and McNemar test according to type of variable. Result: The intervention is statistically significant while considering visual acuity (p < 0.001) and Daily Living Tasks Dependent on Vision questionnaire scores (p< 0.0001) and not significant for optical coherence tomography and Amsler grid findings. Conclusion: The intervention is an effective protocol to be followed in Ayurveda for dry AMD.
ABSTRACT
Acquired disorders of hyperpigmentation affects individuals of all skin types. In Ayurveda, 慥yanga� is a Kshudra roga and a Rakta pradoshaja vikara which mainly affects the complexion of a person by producing Niruja, Shyava varna mandalas over face. The aim of the study was to assess the effect of Bhringaraja bhavitha gandhaka kalpa in Vyanga which is the eighth Gandhaka kalpa mentioned in the eight Taranga of Rasatarangini. Variables like percentage of area involved, darkness and homogeneity were assessed before and after treatment. This paper highlights a case study of Vyanga treated with Bhringaraja bhavitha gandhaka kalpa.
ABSTRACT
Rasa oushadis are the potent Ayurvedic preparations mainly containing metals and minerals. These Oushadis possess wide range of therapeutic efficacy and are considered superior because of their qualities like small dose, quick action, palatability and longer shelf life. Shatpala Gandhaka churna is an important Rasa oushadi described in Vaidya chintamani- Kushtha prakaranam indicated for all types of Kushtha, Grahani, Gulma, Mandagni. Shatpala Gandhaka Churna contains Shuddha Gandhaka, Shuddha Bhallataka, Shuddha Chitrakamula twak, Triphala, Vidanga, Trikatu, Trijataka, Chanaka, and Jeeraka. The main pharmaceutical procedures adopted in this study are Shodhana, Churna nirmana and preparation of capsule of Shatpala Gandhaka Churna. The specific pharmaceutical blend of these contents can result in a more effective formulation. Till now, no research work has been carried out to standardize this formulation. Therefore the present study has been planned to standardize the method of preparation of Shatpala Gandhaka churna according to the method explained in the classical literature.