ABSTRACT
Objective: To study the chemical constituents of the fungus Ganoderma cochlear. Methods: The compounds were isolated by using MCI gel CHP 20P, Sephadex LH-20, RP-18 column chromatography, and preparative TLC. The structures were identified by means of spectroscopic methods. Results: Two phenolic normeroterpenoid and meroterpenoid, cochlearols C and D (1 and 2), together with six benzene derivatives, 3-methoxy-4-hydroxy-phenylethanol (3), 4-hydroxyacetophenone (4), p-hydroxycinnamic methyl ester (5), 2-methoxy-4-hydroxybenzaldehyde (6), 4-hydroxy-3-methoxy benzoic acid (7), and 2-hydroxy-5-ethoxybenzoic acid (8), were isolated from the fruiting bodies of Ganoderma cochlear. Conclusion: Compounds 1 and 2 are new phenolic normeroterpenoid and meroterpenoid, respectively.