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【Objective】 To investigate the resource allocation status of blood testing laboratories in 14 blood stations in Gansu Province, explore the impact of differences in basic conditions on the comprehensive testing ability of laboratories, so as to promote the homogenization and standardization of blood screening capacity in blood stations in Gansu and improve blood safety and effectivenes. 【Methods】 An evaluation index system of laboratory resource allocation was constructed and a question-naire was designed. The data of human resources, infrastructure and key equipment of 14 blood stations were collected. The entropy weight -TOPSIS method was used to evaluate and rank the resource allocation of 14 blood stations. 【Results】 In the comprehensive evaluation of blood testing laboratory resource allocation in 14 blood stations in Gansu, the top three were laboratories A, B and I, and the last three were laboratories G, M and J. On the whole, the main issue was unreasonable structure of human resources: most laboratories had unreasonable age structure; except for Laboratory A, there was no personnel with bachelor's degree or above in laboratories; most laboratories had not established a team with intermediate professional titles. In terms of infrastructure, the size of seven laboratories could not meet the needs of modern laboratory testing, and all eight blood stations had no spare nucleic acid laboratories nor a mutual spare laboratory with other blood stations As for the key equipment, 5 laboratories had no automatic blood grouping diagnostic instrument, 5 laboratories only had one set of enzyme immunoassay detection system, 3 laboratories had no spare equipment for the key equipment, which means if the equipment failure could not be repaired in time, the release of results would be affected. 【Conclusion】 There were significant differences in human resources, infrastructure and key equipment of blood testing laboratories in 14 blood stations in Gansu, which had a great impact on laboratory testing capacity and subsequent development. It is suggested that governments at all levels and health administrative departments optimize the input of laboratory resource allocation according to the blood collection volume of blood stations to gradually narrow the differences in resource distribution between different regions, improve the degree of laboratory automation and optimize the personnel structure, so as to build high-quality and efficient blood testing laboratories and ensure the safety of clinical blood use.
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Objective: Through comparative analysis of the disease burden of occupational pneumoconiosis in Gansu Province from 2010 to 2020, the main influencing factors are screened, and scientific basis is provided for rational allocation of limited health resources, precise management and policy implementation. Methods: In August 2021, survey and collect information on surviving occupational pneumoconiosis patients and dead occupational pneumoconiosis patients diagnosed in Gansu Province from 2010 to 2020, and analyze and calculate indicators such as morbidity, mortality, and disability adjusted of life years (DALY). Analyzing the influencing factors of disease burden usirrg multiple linear regression. Results: From 2010 to 2020, the average annual incidence of occupational pneumoconiosis in Gansu Province was 0.9992/100000, the average annual mortality was 0.897/100000, the cumulative case fatality rate was 25.75%, and the cumulative DALY was 28932.96 person-years. The first stage of occupational pneumoconiosis was the highest among DALY loss (19920.14 person-years), and the DALY loss was positively correlated with the stage of occupational pneumoconiosis. Among occupational pneumoconiosis in Gansu Province, silicosis (13753.66 person-years) and coal worker's pneumoconiosis (13414.73 person-years) caused the highest disease burden, followed by cement pneumoconiosis and asbestos lung. Period, length of service, type of disease, and region are all influencing factors of DALY loss (P<0.05). Conclusion: From 2010 to 2020, the DALY losses caused by occupational pneumoconiosis in Gansu Province showed a fluctuating decrease, with the composition of DALY mainly changing from the loss of life years due to premature death to the loss of years due to injury and disability.
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Humans , Pneumoconiosis/epidemiology , Silicosis/epidemiology , Anthracosis/epidemiology , Asbestos , Cost of Illness , China/epidemiologyABSTRACT
Objective: To analyze the security situation of patients with occupational pneumoconiosis in Gansu Province to lay the foundation for strengthening the security measures for patients with pneumoconiosis. Methods: In August 2020, a follow-up survey was conducted on the current patients with occupational pneumoconiosis diagnosed and surviving in Gansu Province from 1949 to 2019, to obtain the information of industrial injury insurance, employer compensation, medical insurance, subsistence allowance and so on, and analyze their distribution characteristics. The proportion of patients enjoying various security, medical insurance reimbursement and subsistence allowances was tested by chi square. Results: Among the current patients with occupational pneumoconiosis in Gansu Province, 72.0% (5335/7410) enjoyed the benefits of work-related injury insurance, 8.2% (609/7410) enjoyed the compensation paid by the employer, 91.5% (6780/7410) had medical insurance, and 2.8% (204/7410) had no guarantee. Among the patients with occupational pneumoconiosis, 374 enjoyed the minimum living allowance, accounting for 5.05% (374/7410) ; the first diagnosis period with a high proportion of minimum living allowance was phase Ⅲ, accounting for 15.14% (43/284) . Conclusion: The proportion of medical insurance outpatient and inpatient reimbursement of occupational pneumoconiosis patients in Gansu Province is still at a low level. It is suggested that relevant departments should introduce relevant security policies for workers without fixed employers to reduce the economic burden of patients.
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Humans , China/epidemiology , Pleasure , Pneumoconiosis/epidemiologyABSTRACT
Through collecting the relevant moxibustion records of Han medical bamboo slips unearthed in Wuwei and Juyan regions of Gansu province, the situation and characteristics of clinical practice of moxibustion were summarized. In Wuwei Han medical bamboo slips, the contraindications of moxibustion were recorded, with age and time involved. Juyan Han medical bamboo slips mainly recorded the methods of moxibustion at the acupoints located on the back of the body, with clear emphasis and requirement of acupoint selection, single acupoint moxibustion and moxibustion quantity (the numbers of moxa cone) included. These records on bamboo slips initially display the practice and development of moxibustion in Gansu and other northwestern regions of China in the Han Dynasty, providing a certain instruction for the literature research of moxibustion of the excavated Han medical bamboo slips.
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Acupuncture Points , China , Contraindications , Moxibustion , Plant ConeABSTRACT
Objective:To investigate the Leishmania infection status in dogs in canine-derived visceral leishmaniasis endemic areas in Wenxian County and Diebu County of Gansu Province, to provide basis for formulating effective prevention and treatment measures for visceral leishmaniasis. Methods:In 2019, household survey method was used to collect dog basic information (such as gender and age) in villages with higher incidence of previous cases in Wenxian County and Diebu County of Gansu Province; and venous blood of dog was collected, PCR method was used to detect microloop DNA of Leishmania. Results:A total of 537 dogs were investigated, the positive rate of Leishmania detected by PCR was 41.15% (221/537); the positive rates of PCR detection were 64.63% (95/147) and 32.31% (126/390) in Wenxian County and Diebu County, respectively, and the positive rate in Wenxian County was higher than that in Diebu County (χ 2=46.044, P < 0.05). In 35 dogs with clinical symptoms of visceral leishmaniasis, the positive rate of PCR detection was 74.29% (26/35); the positive rates of PCR detection in symptomatically infected dogs were 84.62% (22/26) and 4/9 in Wenxian County and Diebu County, respectively, the positive rate in Wenxian County was higher than that in Diebu County ( P < 0.05). The positive rate of PCR detection was 38.84% (195/502) in 502 asymptomatic dogs; the positive rates of PCR detection were 60.33% (73/121) and 32.02% (122/381) in Wenxian County and Diebu County, respectively, the positive rate in Wenxian County was higher than that in Diebu County (χ 2=39.982, P < 0.05). Conclusions:The infection rates of Leishmania in dogs are high in Wenxian County and Diebu County of Gansu Province, the positive rate of PCR detection in asymptomatic dogs infected with Leishmania is high. This indicates that local residents and dogs are at high risk of infection with Leishmania. It is recommended that relevant departments should enhance residents' awareness of active protection and strengthen efforts to control the Leishmania infection of dogs.
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Objective:To investigate the quality of rehabilitation medical service in tertiary general hospitals in Gansu Province. Methods:Stratified sampling was used to sample tertiary general hospitals in Gansu Province for on-site surveys in 2017. A quality evaluation index system was established in the view of medical service providers, including 17 indicators, based on Donabedian model and experts' opinions. Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) and Rank-sum Ratio were applied to make a comprehensive evaluation on the overall service quality of the hospital rehabilitation medical service. Results:A total of 27 tertiary general hospitals were sampled, in 13 cities/prefectures of Gansu Province. For the structure quality, the compliance rate of the business operation area and the number of beds in the rehabilitation medicine department were 77.78% and 51.85% respectively; while the compliance rates of the physicians, therapists and nurses were all less than 50%. For the process and results quality, the compliance rates were all more than 85%. For the overall quality of rehabilitation medical service, five hospitals were classified as Good, located in Lanzhou, Tianshui and Jiayuguan; 18 hospitals were classified as Medium, located in Longnan, Longdong, Lanzhou and surround, Linxia and Hexi regions; four hospitals classified as Poor, located in Lanzhou and Tianshui. Conclusion:The overall quality of rehabilitation services in the tertiary general hospitals of Gansu Province needs to be improved, and the development of rehabilitation services is uneven in various regions. Comprehensive evaluation provides an important reference to promote the rational distribution of rehabilitation medical resources and improve the quality of rehabilitation medical services.
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Objective To explore the therapeutic effect of Gansu tablets combined with entecavir on patients with severe hepatitis B and the effect on patients’ immune function. Methods A total of 108 cases of severe hepatitis B patients who were treated in our hospital from January 2018 to January 2019 were randomly divided into two groups: entecavir group and combination treatment group, 54 cases each. Entecavir group was treated with entecavir, and combination treatment group was treated with Gansu tablets and entecavir. The levels of AST, GGT, alt, FIB, APTT, Pt, GSH Px, LPO and MDA in serum were measured by enzyme-linked immunosorbent assay. T-lymphocyte subsets were measured by cell analyzer. The therapeutic effect and adverse reactions were compared between the two groups. Results The levels of AST, GGT and ALT in the combined treatment group were significantly lower than those in the entecavir group (P 0.05). Conclusion The use of Gansu tablets combined with entecavir in the treatment of severe hepatitis B patients was able to improve liver function, improve coagulation function, reduce oxidative stress injury, and improve the immune function of patients, demonstrating a potential clinical application value.
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Coronavirus disease-2019 (COVID-19) is an acute infectious disease caused by a 2019 novel coronavirus (2019-nCoV) infection. It is highly contagious, and can spread quickly home and abroad. It has caused a global pandemic. After the outbreak, Gansu province actively responded to the national "integrated Chinese and western medicine(ICWM)" epidemic prevention policy by organizing an expert group on the prevention and treatment of traditional Chinese medicine(TCM) and establishing a joint working mechanism of ICWM. In adherence to the principle of ICWM, it highlighted the advantages of TCM in epidemic prevention, and emphasized early, timely and whole course use of TCM. The expert group continued to summarize in practice and form a series of "Gansu prescriptions", so as to explore the prevention and control strategy of "prevention in advance, timely interruption and reversal, early prevention and cure, and cure in early stage". Before illness, the prevention shall be made in advance by taking Fuzheng Biwen prescription based on constitution differentiation, in order to strengthen the body resistance and removing pathogenic Qi, after the onset, the syndromes were first treated, interrupted and reversed, and Xuanfei Huazhuo prescription and Qingfei Tongluo prescription were administered based on syndrome differentiation, so as to exorcise pathogenic Qi and cure COVID-19 at the early stage, at the beginning stage of recovery, Jianpi Yifei prescription was used to strengthen the spleen and lungs, and harmonize the stomach and resolve dampness, so as to prevent recurrence. In the principle of ICWM, "Gansu prescriptions" were selected based on the constitution differentiation and syndrome differentiation, so as to prevent the occurrence of epidemics, block light and common symptoms from developing to heavy and critical symptoms, improve the clinical efficacy, shorten the course of disease, and reduce the incidence of critical illness, thereby reducing mortality.
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OBJECTIVE：To promote rational use of OTC in the family ，and to provide reference for the formulation of related policy by health administration department. METHODS ：By stratified cluster sampling method ，using residents of 4 cities from Gansu province as objects ，face-to-face questionnaire household survey was conducted in Jan. 2019. The general information of the residents and their family self-medication behaviors were collected ，and the influential factors [tendency factors （including cognition of OTC and attitude towards self-medication ），contributing factors and strengthening factors ，and odds ratio （OR）was used to study the correlation between factors and results] of self-medication behaviors were analyzed by PRECEDE-PROCEED model. Epi Data 3.10 software was used to establish database ，and SPSS 16.0 software was adopted to analyze the family self-medication behavior of residents statistically. RESULTS ：A total of 3 600 questionnaires were sent out ，and 3 111 valid questionnaires were recovered ，with an effective recovery rate of 86.4％. 81.8％（2 541/3 106）of the respondents had self- medication behavior in the past 1 year. The results of binary Logistic regression and χ2 test showed that female residents ，irregular daily life ， no chronic disease ，low monthly family income ，new rural cooperative medical care and urban residents ’medical insurance were more inclined to self-medication. In the tendency factors ，residents who knew that OTC could be purchased in the pharmacy without the doctor ’s prescription （OR＝1.322）， Δ 基金项目 ：国家自然科学基金资助项目 （No.41405108， No.21472077） drug package with OTC logo （OR＝1.397）and the Chinese ＊讲师，硕士。研究方向：药物新制剂、新剂型、新技术。E-mail： herbal medicine also had toxic side effects （OR＝1.750），the 410843130@qq.com possibility of self-medication was greater ；the residents who # 通信作者：教授，博士。研究方向：药物活性分子的设计与合 seldom cleaned the family medicine box （OR＝0.462），quick 成。E-mail：wangshh@lzu.edu.cn and effective drugs （OR＝0.670） and ADR （OR＝0.688） 中国药房 2020年第31卷第11期 China Pharmacy 2020Vol. 31 No. 11 ·1377· were the factors that prevent the occurrence of se lf-medication behavior ，while low drug price （OR＝5.298）was the tendency factor of self-medication behavior. In the contributing factors ，the incidence of self-medication of residents with regular drugs in their home was 2.997 times higher than that those without reserves ；the convenience of self-medication （OR＝1.376），the proximity of drugstores to home （OR＝1.680），the credibility of drug quality （OR＝1.355） had a facilitating effect on the occurrence of self-medication. In the strengthening factors ，the suggestions of relatives and friends （OR＝3.388），books， newspapers and TV network advertisements （OR＝2.043）had a strengthening effect on the occurrence of self-medication. The above factors had a significant effect on the residents ’self-medication（P＜0.05）. CONCLUSIONS ：The family self-medication behavior of residents in Gansu province is common. The residents with higher cognitive level tend to self-medication ；the lower the drug price ，the more likely the self-medication behavior will occur. The factors contributing to the occurrence of self-medication are the regular drugs at home ，the proximity of drugstores to home ，and the credibility of drug quality. The suggestions of relatives and friends，online advertising and other factors are the strengthening factors of the occurrence of self-medication behavior.
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OBJECTIVE: To improve the quality and safety of Radix Codonopsis, Astragalus Root, Angelica Root and other traditional Chinese medicines, aiming at the main problems existing in the main producing areas of genuine medicinal materials of Gansu Chinese materia medica. METHODS Through the investigation and analysis of the producing area, it is tried to use the land rotation system to optimize the soil ring of genuine medicinal materials of Gansu Chinese materia medica, standardize the use of agricultural inputs, and avoid the loss of soil fertility caused by disordered rotation and continuous cropping. RESULTS: AND CONCLUSION: It is of great significance to improve the quality awareness of genuine medicinal materials of Gansu Chinese materia medica, improve and standardize the scientific planting technology, optimize the industrial structure of genuine medicinal materials of Gansu Chinese materia medica, stretch the industrial chain, and strengthen the level of primary processing.
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Gansu province,which spans the Yangtze river,is in the upper reaches of the Yellow river and located at the intersection of the Qinghai-Tibet plateau,the Inner Mongolia plateau and the Loess plateau. All of these areas are highly respected by doctors of all ages as they have enriched the resources of traditional Chinese medicines. In the interaction between the heavens and the earth,the interaction between the people and the future has been passed down to the present. As one of the abbreviations of Gansu province, " Long" is not only the symbol and representative of the Gansu region,but also the symbol of the authentic medicinal materials in Gansu. This paper sorts out the evolution of the name " Long" medicines,the development status and development limitations of " Long" medicines. It is believed that although the production areas of authentic medicinal materials in Gansu have changed in different historical periods,the core varieties have been used ever since. Today,with the great development of the Chinese medicine industry,Gansu province pays attention to the limitations of the current regional and technological competitiveness in the province,and gives full play to its own advantages,which can help the " Long" medicines stand out among the medicinal materials. Furthermore,it lays the foundation for the development of the industry and the application of high quality Chinese herbal medicines in clinical practice.
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China , Drugs, Chinese Herbal , Medicine, Chinese Traditional , Plants, Medicinal , TibetABSTRACT
Objective To analyze the changes of bone strength and body composition in pre- and postmenopausal Dongxiang women and explore the impact of body composition change on bone strength. Methods From Sep. 2016 to Jul. 2018, 203 cases Dongxiang 41-50 year old women (102 cases of premenopause and 101 cases of postmenopause) of Gansu Province were selected by stratified random sampling method, whose bone strength and body composition indexes were measured by ultrasonic bone mineral density meter and body composition analyzer respectively. Results There were lower bone strength and muscle tissue composition in the postmenopausal Dongxiang women (P< 0.05), and there was higher fat tissue composition (P < 0.01). The prevalence of osteoporosis was higher in postmenopausal women (P < 0. 01). Pearson correlation analysis showed that muscle tissue composition was positively correlated with the bone strength (P<0. 01), and it was negatively correlated with fat tissue composition in the pre- and postmenopausal Dongxiang women (P < 0. 0 1). Multivariate linear stepwise regression analysis showed that limb muscle mass and subcutaneous fat mass were a protective factor and a risk factor for bone strength in pre- and post-menopausal Dongxiang women, respectively. Conclusion The bone strength of Dongxiang women was determined by muscle and fat tissue, and associated with the distribution of body composition. The relationship between bone strength and body composition was not affected by menopause. Menopause was an important factor that increased the incidence of osteoporosis in Dongxiang women, and we should reinforce osteoporosis prevention in postmenopausal Dongxiang women. Strengthen physical exercise, increase limb muscle mass and reduce subcutaneous fat could contribute to increase bone strength and prevent osteoporosis in in the pre- and post-menopausal Dongxiang women.
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Objective: To evaluate the safety and efficacy of occlusion therapy for patent ductus arteriosus (PDA) infants in Gansu plateau and sub-plateau of China. Methods: A total of 300 PDA infants treated in Gansu Provincial People's Hospital between Jan. 2008 and Jan. 2018, including 123 patients from plateau area and 177 patients from sub-plateau area, were enrolled in this study. Their ages ranged from 6 months to 3 years. Anterior right heart catheter was blocked for measuring pulmonary artery pressure before occlusion during surgery. Different occlusion devices were selected according to the characteristics of PDA during the operation. Occlusion treatment for PDA patients with mild pulmonary hypertension was processed and testing occlusion was given to patients with moderate to severe pulmonary hypertension. After 1, 3, and 6 months follow-up, electrocardiogram, echocardiography and other data were examined, and changes in pulmonary artery pressure were evaluated based on the rate of tricuspid regurgitation. Results: A total of 300 patients receiving angiography showed defects, with the defect diameter being 1-10 (4.5 ± 2.8) mm before operation. After occlusion, 293 infants had no residual shunt. Totally 299 patients were successfully operated, and 97 patients with moderate to severe pulmonary hypertension were tested for hyperoxia and 21 infants with oxygen saturation <95% were given testing occlusion operation. And 235 patients were successfully blocked with PDA occlude, 53 micro-arterial catheters were occluded with German PFM Duct-Occlud, and 11 treated with ventricular septal defect occlude. One case aged 3 years old gave up treatment due to elevation of pulmonary artery pressure immediately after occlusion. Pulmonary systolic pressure and mean pulmonary artery pressure decreased in 299 patients 6 months after operation. Conclusion: Occlusion therapy is a reliable method for PDA infants in plateau and sub-plateau areas of Gansu Province, China, with definite curative effect and high success rate. Testing occlusion is a reliable method for identifying severe pulmonary hypertension, and choosing an appropriate occlusion device according to the individual conditions can achieve promising clinical outcomes.
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Objective To establish the medical reference range of amino acid and acyl car-nitine tandem mass spectrometry in normal neonates in Gansu province,and provide the basis for the determination of amino acid and acyl carnitine test results in the screening of neonatal genetic metabolic diseases.Methods A non derivatization tandem mass spectro-metry kit was used to screen 77 957 samples of neonates in Gansu province.Statistical soft ware SPSS19.0 was used to analyze the 95％ reference range of 11 amino acids and 31 kinds of acylcarnitine indexes.Results The medical reference value(μmol/L) of the series mass spectra of newborn genetic metabolic diseases in Gansu province was established:ALA (216.17 ～ 727.58),ARG (1.80～33.03),CIT (4.87～30.67),GLY (183.43～841.46),LEU (79.85～289.45),MET (3.32～25.86),ORN (34.09～225.15),PHE (27.04～83.37),PRO (79.44～337.59),TYR (37.61～177.79),VAL (59.31～250.95),C0 (9.35～45.35),C2 (2.62～25.40),C3 (0.46～3.3),C3DC_C4OH (0.02～0.20),C4 (0.08～0.31),C4DC_C5OH (0.10～0.32),C5 (0.05～0.30),C5:1 (0.00～0.01),C5DC_C6OH (0.04～0.22),C6 (0.01～0.06),C6DC (0.03～0.13),C8 (0.02～0.08),C8:1 (0.05～0.31),C10 (0.02～0.12),C10:1 (0.03～0.10),C10:2 (0.01～0.10),C12 (0.02～0.13),C12:1 (0.02～0.10),C14 (0.07～0.30),C14:1 (0.03～0.13),C14:2 (0.01～0.03),C14OH (0.00～0.02),C16 (0.59～4.91),C16:1 (0.03～0.30),C16:1-OH (0.01～0.08),C16OH (0.01～0.03),C18 (0.29～1.30),C18:1 (0.57～2.32),C18:1-OH (0.01～0.05),C18:2 (0.08～0.51) and C18OH (0.00～0.02).Conclusion The establishment of the medical reference range of the normal neonatal dryblood spot amino acid and acyl carnitine tandem mass spectrometry in Gansu province can provide reference for the determination of the results of the cluster mass spectrometry in this region.
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Objective To explore the relationship between the volatile components in Angelicae Sinensis Radix from different regions of Gansu Province and its growing environment with metabolomics based on GC-MS. Methods The GC-MS method was used for detecting the volatile components in Angelicae Sinensis Radix from 31 different regions in Gansu province, and principal component analysis (PCA) and partial least squares (PLS) methods were used for analyzing and evaluating its relationship with the growing environment. Results The results of PCA showed that the volatile components in Angelicae Sinensis Radix from different regions in Gansu province were related to the altitude and the soil types. The PLS method could divide 31 samples of Angelicae Sinensis Radix from different regions in Gansu Province into three groups according to the difference of altitude. There were significant differences in the volatile components in the samples taken at different altitude regions. After analyzing linear loading plots from PCA and PLS, 11 charateristic components were screened out, including 7 compounds were identified by the retrieval of NIST11 database. Conclusion The volatile components in Angelicae Sinensis Radix from different regions in Gansu Province are closely related to the altitude and the soil type.
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Developing the Chinese herbal medicine industry of Gansu is the measure to find new economy point of growth, construct characteristic industry and distinctive industry. Industry chains should be divided scientific, constructed completely and balanced. Industrial clusters about the formation model should be figured out.The excitation mechanism of enterprise-university-research institute cooperation should be constructed. Appropriate means of propaganda should be chosen. Talent training supporting system should be constructed. The supervision should be strengthened.
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OBJECTIVES@#To investigate the genetic polymorphisms of 27 Y-STR in Dongxiang population of Gansu province, and to explore the population genetic relationship and the value of forensic application.@*METHODS@#The genotyping of 27 Y-STR loci in 526 unrelated male individuals in Dongxiang population of Gansu province were detected by STRtyper-27Y kit. The allele frequencies and haplotype diversity were also calculated. Combining with other genetics data of 14 loci in same populations, which have been published at home and abroad, the genetic distance and clustering relationship in Dongxiang population of Gansu province were calculated.@*RESULTS@#Totally 55 haplotypes were found in the DYS385a/b biallelic loci, 39 haplotypes in DYF387S1 loci, and 4-16 alleles in the rest 23 single copy STR loci. The GD value was from 0.453 9 （DYS391） to 0.957 5 （DYS385a/b）. Totally 471 haplotypes were observed in 27 Y-STR loci in 526 individuals, and the value of haplotypes diversity was 0.999 5. The genetic distance between Dongxiang and Tibetan populations of Gansu province was the closest （0.068 2）, while it was the longest between Dongxiang population in Gansu province and Han population in Henan province （0.084 7）. The result of dimensional analysis established upon the genetic distance was basically matched with that of the cluster analysis.@*CONCLUSIONS@#The 27 Y-STR loci show a high genetic polymorphism in Dongxiang population of Gansu province, which has significance for the Y-STR database establishment, population genetics study and forensic practice.
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Humans , Male , Alleles , Asian People/genetics , China , Chromosomes, Human, Y , Gene Frequency , Genetics, Population , Haplotypes , Microsatellite Repeats , Polymorphism, Genetic/genetics , Population GroupsABSTRACT
Objective The aim of this study was to analyze of the prevalence of Norovirus in the foodborne disease surveillance population in Baiyin City in 2015,and provide scientific basis for the prediction,early warning,prevention and control of foodborne diseases caused by Norovirus.Methods A questionnaire survey was conducted on the cases of foodborne disease surveillance.Fecal specimen were collected,and Norovirus GⅠ and GⅡ were detected by real time fluorescence quantitative polymerase chain reaction.Results Three hundred and forty-four foodborne disease cases were reported,78 cases were positive,and the detection rate was 22.7％.Five cases were positive for Norovirus GⅠ,and 71 cases for GⅡ.Two cases were positive for both GⅠ and GⅡ.Forty-six cases were male and 32 cases were female.The oldest patient was 83 years old,and the youngest was only 3 months with an average age of 20.3.Conclusion Norovirus was one of the main foodborne pathogens in the city,and the main epidemic was GⅡ in autumn and winter.Public education and health monitoring should be strengthened.
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OBJECTIVE:To provide reference for improving the food and drug inspection and testing system in Gansu prov-ince. METHODS:The food and drug inspection and testing institutions in Gansu province were investigated by using questionnaires and interview. Information about resource allocation,operational capacity and business scope in various levels of food and drug in-spection and testing institutions in Gansu province were collected. Problems existing in food and drug inspection and testing system in Gansu province were analyzed,and countermeasures were put forward. RESULTS & CONCLUSIONS:The food and drug in-spection and testing system in Gansu province is not perfect,showing unreasonable resource allocation,lack of inspection and test-ing resources as a whole,low resource utilization,imperfect management mechanism,weak normativity and other problems. In or-der to achieve the improvement of food and drug inspection and testing system in Gansu province,countermeasures were put for-ward,including optimizing resource allocation of inspection and testing,enhancing facility and capacity,improving the utilization of existing resources,improving management mechanism,process and standard.
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Objective To analysis the family management of patients with serious mental illness in Gansu prov-ince, and evaluate its effectiveness to lay the foundation for the better community-based rehabilitation management and treatment for the people with serious mental illness. Method According to Treatment-management specification of severe mental illness (2012) and specification of national basic public health services (2011), the information such as home ther-apy, medicine taken, and dangerous behavior happened were collected from patients who were confirmed as serious men-tal illness in January 2015 to April 2016 in Gansu province. Result Up to April 30th, 2016, totally 70538 serious mental illnesses were identified, and about 81.10%(57195) were under management. The rate of treatment of serious mental ill-ness was 69.9%(48009/68663) in Gansu province, and Bipolar affective disorder (76.0%) was the highest (P<0.001). The rate of taking medication in patients under family-management was 42.16%(24113/57195), and the rate of taking regular medication was 24.74%(14150/57195). The rate of taking medication in Paranoiac psychosis patients (51.98%) was the highest (P<0.001), and the rate of taking regular medication in Mental disorders caused by epilepsy (31.02%) was the highest (P<0.001). Conclusion The rate of family-management, treatment, taking medication and take regular medica-tion of serious mental illness in Gansu province are all below the national average level. A special training should be giv-en to medical professionals to strengthen their capacity to treat serious mental illness.