ABSTRACT
RESUMEN El sindrome de Gardner- Diamond conocido también como púrpura psicógena o síndrome de autosensibilización eritrocitaria es muy poco frecuente. Se presenta el caso de un hombre de 50 años, blanco, ingresado en el Servicio de Medicina Interna del Hospital Clínico Quirúrgico Docente "Faustino Pérez Hernández" por síndrome febril agudo, cefalea holocraneana, epistaxis y hemolacria. En el examen físico realizado se notó la salida de lágrimas con sangre, por el ángulo interno de ambos ojos y epistaxis. La inyección intradérmica en la cara dorsal del muslo izquierdo de 0,1 mL de sangre autóloga, no indujo reacción equimótica. La inyección de 0,1 mL de solución salina al 0,9 % como control en el muslo contralateral resultó negativa. Sobre la base del examen clínico y otras pruebas, se concluyó como un Síndrome de Gardner-Diamond. Esta infrecuente enfermedad debe ser considerada en el diagnóstico diferencial de un síndrome purpúrico de etiología no bien precisada, fundamentalmente en pacientes con problemas psiquiátricos.
ABSTRACT The Gardner-Diamond syndrome, also known as psychogenetic purpura or erythrocyte autosensitization syndrome is very few frequent. The case of a white patient aged 50 years is presented. He entered the Service of Internal Medicine of the Teaching Clinic-surgical Hospital "Faustino Pérez Hernández" because of an acute fever syndrome, holocraneal headache, epistaxis and haemolacria. At the physical examination it was stated the flow of tears with blood, through the internal angle of both eyes and epistaxis. The intradermal injection of 0.1 ml of autologous blood in the left thigh dorsal side did not induce an ecchymotic reaction. The injection of 0.1 ml of 0.9 % saline solution as control in the contralateral side was negative. On the basis of the clinical examination and other tests, the authors arrived to the conclusion it is a Gardner-Diamond syndrome. This infrequent disease should be considered in the differential diagnosis of a purpuric syndrome of non-good précised etiology, mainly in patients with psychiatric problems.
Subject(s)
Humans , Male , Middle Aged , Gardner Syndrome/etiology , Gardner Syndrome/history , Gardner Syndrome/pathology , Gardner Syndrome/epidemiology , Gardner Syndrome/diagnostic imaging , Epistaxis/diagnosis , Fever/diagnosis , Headache/diagnosisABSTRACT
Gardner–Diamond syndrome (GDS), or autoerythrocyte sensitisation, is a rare cause of recurrentpainful bruising with a typical anamnesis and prodrome. We describe a patient with GDS and discussthe literature surrounding this unique condition.
ABSTRACT
El síndrome de Gardner-Diamond o púrpura psicógena es una vasculopatía de presunto origen autoinmune que se caracteriza por una reacción cutánea localizada, asociada a situaciones de estrés emocional. Se presenta el caso de una paciente con lesiones equimóticas, dolorosas y de aparición intermitente, relacionadas con diversos eventos estresores, que habían sido manejadas como manifestación de lupus
Gardner-Diamond syndrome or psychogenic purpura is an vasculopathy characterized by a localized cutaneous reaction, associated with episodes of emotional stress or mental illness as trigger factors. A case of a female patient with multiple, intermittent, nodular, ecchymotic and painful lesions related to various stressing events that was treated as lupus is reported below
Subject(s)
Humans , Lupus Erythematosus, Cutaneous , Diagnosis, DifferentialABSTRACT
Se presenta el caso de una mujer de 44 años, blanca, ingresada en el Servicio de Medicina Interna del Hospital Clinicoquirúrgico Docente "Miguel Enríquez" por síndrome febril agudo y hematuria. En el examen físico realizado se notó la salida de lágrimas con sangre muy fluida, por el ángulo externo del ojo izquierdo. La inyección intradérmica en la cara dorsal del muslo derecho de 0,1 mL de sangre autóloga, indujo una reacción equimótica dolorosa en el sitio de la inyección. La inyección de 0,1 mL de solución salina al 0,9 % como control en el muslo contralateral, resultó negativa. Sobre la base del examen clínico y estas pruebas, se concluyó como un Síndrome de Gardner-Diamond. Esta entidad debe ser considerada en el diagnóstico diferencial de un síndrome purpúrico de etiología no bien precisada, fundamentalmente en pacientes con problemas psiquiátricos.
This is the case of a white woman aged 44, admitted in the Internal Medicine Service of "Miguel Enríquez" Clinical Surgical Hospital due to acute febrile syndrome and hematuria. At physical examination performed we noted a very high level of watering with presence of blood by left angle of left eye. The intradermal injection of 0,1 ml of autologous blood in dorsal part of right thigh, induced a painful ecchymotic reaction in injection site. The injection of 0.1 ml of 0,9% saline solution as control in contralateral thigh was negative. On the base of clinical examination and these tests, we conclude that it was a Gardner-Diamond syndrome. This entity must to be considered in differential diagnosis of a purpuric syndrome of a non-well established etiology, mainly in patients presenting with psychiatric disorders.
ABSTRACT
Autoerythrocyte sensitization syndrome (Gardner-Diamond syndrome), also known as painful bruising syndrome or psychogenic purpura, is characterized by sudden and spontaneous painful bruising and swelling on both extremities, and is a psychologically induced painful bruising condition. The exact etiology of the syndrome is an enigma, even today. It occurs primarily in young to middle-aged women who usually have psychogenic disorders. A diagnosis of this syndrome is made on the basis of the clinical history, dermatological examination complemented by a positive autoerythrocyte sensitization test, psychiatric evaluation and the absence of any organic cause. We present a 20-year-old man with characteristic features of this syndrome, who had a positive autoerythrocyte sensitization test. To our knowledge, this is the first case in an adult male reported in the Korean literature.
Subject(s)
Adult , Female , Humans , Male , Young Adult , Complement System Proteins , Diagnosis , Extremities , PurpuraABSTRACT
No abstract available.