ABSTRACT
Generalized perforating granuloma annulare is a rare variety of granuloma annulare presenting a distinct clinical pattern. We, herein, report a case of generalized perforating granuloma annulare with diabetes mellitus, which developed on a 73 year-old-female who had pruritic generalized small papular lesions with central umbilication, especially on the back and lower extremities for 1 month. Histopathologic examination showed an epidermal perforation and transepidermal elimination of necrobiotic material. The epidermal perforation was communicated with areas of necrobiotic collagen surrounded by palisading granuloma in the dermis.
Subject(s)
Collagen , Dermis , Diabetes Mellitus , Granuloma Annulare , Granuloma , Lower ExtremityABSTRACT
Generalized perforating granuloma annulare is a rare atypical type of granuloma annulare. It has typical clinicopathological features. We report a case of generalized perforating granuloma annulare in a 31-year-old woman. In our case, erythematous scaly and umbilicated papules were on the whole body, and histopathological finding showed that the transepidermal elimination and the deposition of degenerated collagen in the dermis with palisading granuloma.