ABSTRACT
@#At present, gene detection technology has become increasingly mature and integrated with multi-disciplinary, which provides help for clinicians to diagnose, treat andprognosis of the disease. In recent years, gene detection technology in diabetic retinopathy(DR)has made some progress, mainly applied to the risk factors of diabetic retinopathy and follow-up personalized treatment plan. Therefore, we summarize and analyze the gene loci related to diabetic retinopathy that can be detected by gene detection technology.
ABSTRACT
Recently, genome-wide association study (GWAS)has achieved great success in illuminating genetic basis of complex diseases. GWAS of type 2 diabetes is regarded as a paradigm of genetic dissection of complex human diseases, which are caused by both genetic and environmental factors. Some basic facts of GWAS,as well as implementation of GWAS in type 2 diabetes, are reviewed in this article.