Perioperative blood management strategies for elderly orthopedic patients / 中国输血杂志

With the arrival of an aging society, the number of orthopedic geriatric patient who require surgical treatment is also rapidly increasing. Elderly patients have decreased hematopoietic function, and perioperative blood management is difficult and challenging. This article aims to elaborate on the perioperative blood management strategies for orthopedic geriatric patients, including the diagnosis and treatment of preoperative anemia, specific measures to reduce perioperative blood loss, and blood transfusion strategies.

Hiponatremia en pacientes geriátricos con insuficiencia cardiaca / Hyponatremia in geriatric patients with heart failure

Introducción: La hiponatremia es la alteración electrolítica más frecuente en el paciente geriátrico. Existen evidencias que la asocian a un peor pronóstico en pacientes con insuficiencia cardiaca. Objetivo: Caracterizar los pacientes geriátricos ingresados con hiponatremia al ingreso e insuficiencia cardíaca. Método: Se realizó un estudio descriptivo, longitudinal y prospectivo durante el año 2018 en el Hospital Universitario Clínico Quirúrgico Calixto García que incluyó 260 pacientes con insuficiencia cardíaca e hiponatremia al ingreso. Para el análisis estadístico de los datos reutilizaron la prueba de chi cuadrada y el análisis multivariado de ANOVA para la asociación entre variables. Resultados: La edad media fue 72,6 ± 8,2, predominaron las mujeres (55,0 por ciento). Prevaleció la puntuación de Charlson 3-4 (33,8 por ciento), la fracción de eyección conservada, 70,8 por ciento; clase funcional III, 33,8 por ciento; estadía menor a 6 días, 43,1 por ciento y fallecieron 51,9 por ciento de la muestra estudiada. Se asociaron significativamente con la mortalidad al egreso, el índice de comorbilidad y la clase funcional III-IV, p< 0,05. Conclusiones: Existe una elevada mortalidad en pacientes geriátricos hospitalizados por insuficiencia cardiaca e hiponatremia al ingreso asociada a la presencia de comorbilidad y a la clasificación de la insuficiencia cardiaca(AU)

Introduction: Hyponatremia is the most frequent electrolyte alteration in geriatric patients. There is evidence that associates it with a worse prognosis in patients with heart failure. Objective: To describe geriatric patients admitted with hyponatremia on admission and heart failure. Method: A descriptive, longitudinal and prospective study was carried out in 2018 at Calixto García Surgical Clinical University Hospital, including 260 patients with heart failure and hyponatremia on admission. For the statistical analysis of the data, they reused the chi-square test and the multivariate analysis of ANOVA for the association between variables. Results: The mean age was 72.6 ± 8.2, women predominated (55.0 percent). Prevalence was observed in the Charlson score 3-4 (33.8 percent), the ejection fraction preserved (70.8 percent); functional class III was 33.8 percent; 43.1 percent stayed less than 6 days and 51.9 percent of the sample studied died. They were significantly associated with mortality at discharge, the comorbidity index and functional class III-IV, p <0.05. Conclusions: There is a high mortality in geriatric patients hospitalized for heart failure and hyponatremia on admission associated with the presence of comorbidity and the classification of heart failure(AU)

Abdomen agudo quirúrgico en el paciente geriátrico / Surgical Acute Abdomen in the Geriatric Patient

RESUMEN Introducción: El abdomen agudo es causa frecuente de ingreso hospitalario en pacientes geriátricos. Objetivo: Caracterizar el comportamiento del abdomen agudo quirúrgico en el paciente geriátrico en un servicio de cirugía general. Métodos: Se realizó un estudio observacional descriptivo longitudinal de corte transversal en 169 pacientes. Los datos procedieron de las historias clínicas del Hospital Universitario "Manuel Ascunce Domenech" de Camagüey, desde enero de 2014 a diciembre de 2016 y se procesaron mediante estadística descriptiva, relacionándose algunas variables de manera no inferencial. Resultados: El 52,2 por ciento de los pacientes eran hombres. El 42,6 por ciento tenía edades entre 60 y 69 años. El 28,9 por ciento presentaron la oclusión intestinal como etiología. Hubo un 39,5 por ciento de complicaciones, el 54,5 por ciento de ellas fueron infecciosas. La mortalidad fue de un 22,5 por ciento. El 26,6 por ciento de los fallecidos presentaba oclusión intestinal. Conclusiones: Casi una décima parte de los pacientes fallecieron, la peritonitis fibropurulenta y el choque séptico fueron las causas más frecuentes de los decesos. La oclusión intestinal como causa de abdomen agudo pareció influir en la mortalidad de la muestra estudiada(AU)

ABSTRACT Introduction: Acute abdomen is a frequent cause of hospital admission in geriatric patients. Objective: To characterize the occurrence of acute surgical abdomen in the geriatric patient in a general surgery service. Methods: An observational, descriptive, longitudinal and cross-sectional study was carried out with 169 patients. The data were obtained from the medical records of Manuel Ascunce Domenech University Hospital in Camagüey, from January 2014 to December 2016, and were processed using descriptive statistics, relating some variables in a noninferential way. Results: 52.2 percent of the patients were men. 42.6 percent were aged between 60 and 69 years. 28.9 percent presented intestinal occlusion as an etiology. There were 39.5 percent of complications, 54.5 percent of which were infectious. Mortality was 22.5 percent. 26.6 percent of the deceased had intestinal obstruction. Conclusions: Almost one tenth of the patients died, with fibrinopurulent peritonitis and septic shock being the most frequent causes of death. Intestinal occlusion as a cause of acute abdomen appeared to influence mortality in the sample studied(AU)

Xerostomía en la población geriátrica del municipio Marianao. 2017 / Xerostomia in Marianao municipality geriatric population in 2017

RESUMEN Fundamentación: La xerostomía es un problema de salud en una parte de la población geriátrica y se observa a nivel mundial una tendencia a su aumento en países en desarrollo. Objetivo: Caracterizar el comportamiento de la xerostomía en la población geriátrica, pertenecientes a la casa comunidad del adulto mayor del municipio Marianao. Metodología: Estudio descriptivo y transversal en 59 pacientes pertenecientes a la casa comunidad del adulto mayor. Las variables utilizadas fueron: edad, sexo, secreción salival, consumo de fármacos y enfermedades bucales. Resultados: El 93.2 % de la población correspondió al sexo femenino, la edad más afectada fue entre 70 y 79 años (30.5 %), los medicamentos más consumidos fueron los antihipertensivos (55.3 %) y los diuréticos (35.7 %), el 40.6 % de los pacientes que presentaron xerostomía padecen de disfunción masticatoria. Conclusiones: Predominó el sexo femenino con xerostomía y el grupo de estudio está mayormente expuesto a la polifarmacia, reduciendo el flujo salival e incidiendo en la disfunción masticatoria.

ABSTRACT Background: Xerostomia is a health problem in a part of the geriatric population, at present, there is a worldwide tendency to increase it in developing countries. Objective: To characterize the behavior of the xerostomia in the geriatric population, at the Aged Community House in Marianao municipality. Methodology: Descriptive and cross-sectional study in 59 patients belonging to the aged home community. The variables used were: age, sex, salivary secretion, drug consumption and oral diseases. Results: 93.2% of the population corresponded to the female sex, the most affected age was between 70 and 79 years (30.5%), the most consumed drugs were the antihypertensive drugs (55.3%) and diuretics (35.7%), 40.6% of patients who presented xerostomia suffer from masticatory dysfunction. Conclusions: The female sex predominated with xerostomia and the study group is mostly exposed to polypharmacy, reducing the salivary flow and affecting the masticatory dysfunction.

De la enfermera general a la enfermera geriátrica / From the general nurse to the geriatric nurse

Introducción: la definición enfermera está estrechamente ligada a su función y en consecuencia la definición de enfermería. Es un profesional que se dedica al cuidado de la salud de los seres humanos. La historia de la enfermería profesional comenzó con Nightingale, sus postulados sobre la formación de las enfermeras en la instrucción de principios científicos y experiencias prácticas para el desarrollo de habilidades sirvieron de modelo universal para las primeras escuelas de enfermería, lo que devino en la formación de enfermeras en las diferentes especialidades, como la atención al paciente geriátrico. Este temprano acierto en la formación de recursos de enfermería se refleja en las diferentes definiciones de enfermera que se aprecian en las diversas teorías aplicadas a enfermería. Objetivo: indagar sobre la evolución de la definición de enfermera, teniendo en cuenta su indispensable valor en la atención al paciente anciano. Métodos: se realizó análisis de contenido de documentos, que incluyó distintos libros de texto, artículos originales y de revisión publicados de 1993 al 2015 con las siguientes palabras clave, enfermera, geriatría, enfermería en SciELO, Dialnet y elsevier, se identificaron y revisaron 20 artículos de los que fueron útiles 11, así como monografías de varias revistas que permitió el análisis histórico lógico de la evolución de la categoría. Conclusiones: la indagación sobre la evolución de la definición de enfermera geriátrica permitió definir operacionalmente esta categoría, a partir de las particularidades de la enfermera geriátrica y el reto que enfrenta la demanda de servicios de geriatría y de enfermería en correspondencia con la satisfacción de necesidades al paciente geriátrico(AU)

Introduction: The definition of nurse is closely related to the professional's function and, in consequence, the definition of nursing, too. That person is a professional dedicated to caring for the health of human beings. The history of professional nursing started with Nightingale: her postulates about the training of nurses in the instruction of scientific principles and practical experiences for the development of skills served as a universal model for the first nursing schools, which later became the training of nurses in the different specialties, such as the care for the geriatric patient. This positive aspect at the beginning in the training of nursing resources is reflected in the deferent definitions of nursing perceived in the different theories applied to nursing. Objective: Inquire into the evolution of the definition of nurse, considering the indispensable value in the care for the elderly patient. Methods: Documental contents analysis was carried out, which included different text books, original and review articles published from 1993 and 2015 with the following key words: nurse, geriatrics, nursing, in SciELO, Dialnet and Elsevier. We identified and reviewed 20 articles, out of which 11 were useful, as well as monographs from several journals, which permitted the logical-historical analysis of the category's evolution. Conclusions: Inquiries into the evolution of the definition of geriatric nurse permitted to operationally define this category, from the particularities of the geriatric nurse and the challenge before the geriatric and nursing services demand in correspondence with the meeting of the geriatric patient's needs(AU)

Antibiotic resistance profile of the bacterial strains isolated from geriatric patients in hospitals across China：data from CHINET Antimicrobial Resistance Surveillance Program 2005-2014 / 中国感染与化疗杂志

Objective To analyze the resistance proifle of bacterial strains isolated from geriatric patients in 17 hospitals across China from 2005 to 2014.Methods A total of 17 representative general hospitals were involved in this program. Bacterial susceptibility testing was carried out by means of a uniifed protocol using Kirby-Bauer method and MIC determination. The results were analyzed according to CLSI 2014 breakpoints.Results The proportion of the strains isolated from geriatric patients among all the clinical isolates increased with time from 30.0% in 2005 to 32.7% in 2014. A total of 159 888 clinical isolates were collected from geriatric patient during the period from 2005 to 2014, about 33.1% of the whole patient population. Gram negative organisms and gram positive cocci accounted for 77.1% (123 229/159 888) and 22.9% (36 659/159 888), respectively. Majority (92.8%, 148 376/159 888) of the isolates were from inpatients and more than half (55.2%, 88 201/159 888) of the isolates were from sputum or other respiratory tract specimens. Methicillin-resistant strains inS. aureus (MRSA) and coagulase negativeStaphylococcus (MRCNS) accounted for an average of 67.1% and 75.9%, respectively. The resistance rates of methicillin-resistant strains to β-lactams and other antimicrobial agents were much higher than those of methicillin-susceptible strains. No staphylococcal strains were found resistant to vancomycin, teicoplanin or linezolid. Some strains ofE. faecalis (0.4%) andE. faecium (4.6%) were resistant to vancomycin, which was higher than average national level (0.3%, 3.2%). Vancomycin-resistant strains ofE. faecalisandE. faecium were mainly VanA type and VanB type based on their phenotype. The prevalence of penicillin-susceptibleS. pneumoniae strains was 78.2%, slightly lower than the 95.0% in Chinese adults in year 2014. The prevalence of ESBLs-producing strains was 67.5% inE. coli, 40.4% inKlebsiella (K. pneumoniae andK. oxytoca) and 34.3% inProteus mirabilis isolates on average. The strains ofEnterobacteriaceae were still highly susceptible to carbapenems (<10% resistant), followed by amikacin and the beta-lactam and beta-lactamase inhibitor combinations. Overall, 35.9% and 33.0% of theP. aeruginosa strains were resistant to imipenem and meropenem. More than 50% of theA. baumannii strains were resistant to imipenem and meropenem. The prevalence of extensively drug-resistant (XDR)P. aeruginosa (4.0%-1.8%) was higher than the average national level (2.1%-1.6%). The prevalence of XDR A. baumannii (19.2%-15.5%) and XDREnterobacteriaceae (0.1%-1.0%) was lower than the average national level (21.4%-19.7% and 0.3%-3.2%).Conclusions The proportion of clinical isolates from geriatric patients is different from average national level at the same period. The isolates from geriatric patients are more likely from inpatients, respiratory tract specimens and more likely non-fermentative gram-negative bacilli compared to average national level. The proportion of fastidious bacteria andEnterobacteriaceae species is generally lower than average national level. MRSA, VRE, ESBLs-producing strains and XDRP. aeruginosa are more prevalent in geriatric patients than in general Chinese patient population. This study suggests that surveillance of antimicrobial resistance for the clinical isolates from geriatric patients is very important for rational antimicrobial therapy.

Effect of low dose dexmedetomidine premedication on propofol consumption in geriatric end stage renal disease patients / Efeito da pré-medicação com dose baixa de dexmedetomidina sobre o consumo de propofol em pacientes geriátricos com doença renal em estágio terminal

ABSTRACTBACKGROUND AND OBJECTIVE: Sedation in dialysis dependent end-stage renal disease patients requires caution as a result of performing high doses of sedatives and its complications. Multidrug sedation regimens might be superior and advantage on lesser drug consumption and by the way adverse events which occur easily in end-stage renal disease patients. We evaluated the effects of dexmedetomidine premedication on propofol consumption, sedation levels with Observer's Assessment of Alertness and Sedation scores and the bispectral index and the hemodynamic changes, potential side effects in geriatric patients with end-stage renal disease who underwent hip fracture surgery under spinal anesthesia.METHOD: In this randomized, controlled, double-blind study 60 elderly patients (age ≥ 65 years) with end-stage renal disease and hip fracture scheduled for anterograde femoral intramedullary nailing were assigned to groups that received either intravenous saline infusion (Group C) or dexmedetomidine 0.5 g/kg/10 min infusion for premedication (Group D). All the patients received propofol infusion after the induction of the spinal anesthesia.RESULTS: Total propofol consumption, propofol dose required for targeted sedation levels according to Observer's Assessment of Alertness and Sedation scores and bispectral index levels, recovery times were significantly lower in Group D (p < 0.001). The time to reach to Observer's Assessment of Alertness and Sedation score 4 and to achieve bispectral index ≤ 80 was significantly lower in Group C compared with Group D (p < 0.001). Adverse events were similar in both groups.CONCLUSION: Dexmedetomidine premedication lowers intraoperative propofol consumption to maintain targeted level of sedation. Therefore low dose dexmedetomidine premedication in addition to propofol infusion might be an alternative in geriatric patients with end-stage renal disease for sedation.

RESUMOJUSTIFICATIVA E OBJETIVO: A sedação em paciente dependente de diálise com doença renal em estágio terminal (DRET) requer cautela como resultado da administração de altas doses de sedativos e suas complicações. Os regimes de sedação com múltiplas drogas podem ser superiores e vantajosos em relação ao consumo menor de drogas e aos eventos adversos que ocorrem facilmente em pacientes com DEET. Avaliamos os efeitos da pré-medicação com dexmedetomidina sobre o consumo de propofol, os níveis de sedação com os escores da Observer's Assessment of Alertness and Sedation (OAA/S) e do índice bispectral (BIS), as alterações hemodinâmicas e os potenciais efeitos colaterais em pacientes geriátricos com DRET submetidos à cirurgia para fratura de quadril sob raquianestesia.MÉTODO: Neste estudo randômico, controlado e duplo-cego, 60 pacientes idosos (idade ≥ 65 anos), com DRET e fratura de quadril, agendados para fixação intramedular de haste femoral anterógrada foram designados para grupos para receberam infusão intravenosa de solução salina (Grupo C) ou pré-medicação com infusão de 0,5 mg kg/10 min de dexmedetomidina (DEX) (Grupo D). Todos os pacientes receberam infusão de propofol após a indução da raquianestesia.RESULTADOS: O consumo total de propofol, a dose de propofol necessária para os níveis-alvo de sedação de acordo com os escores da OAA/S, os valores do BIS e os tempos de recuperação foram significativamente menores no Grupo D (p < 0,001). O tempo para atingir o escore 4 na OAA/S e valores BIS ≤ 80 foi significativamente inferior no Grupo C em comparação com o Grupo D (p < 0,001). Os eventos adversos foram semelhantes em ambos os grupos.CONCLUSÃO: A pré-medicação com dexmedetomidina reduz o consumo de propofol no intraoperatório para manter o nível-alvo de sedação. Portanto, a pré-medicação com DEX em dose baixa em combinação com infusão de propofol pode ser uma opção para sedação em pacientes geriátricos com DRET.

Preformed stainless steel crown in special conditions in adults: Two case reports.

Stainless steel crowns (SSC) are extensively used in child patients. They are mainly used following the pulp therapy in deciduous teeth. They are also used in multi‑surface restoration, as an abutment in space maintainers, correction of anterior tooth cross bite, restoration of hypoplasic teeth, etc. In permanent teeth, they are mainly used as interim restorations following root canal treatment in first molars prior to the eruption of permanent second molars. The main advantage of SSC is its limited chair side time, durability and ease of placement. Patients with conditions such as pregnancy and old age who cannot tolerate multiple and long appointments can greatly benefit from the use of SSC. Though SSC can be used by other dental specialties very effectively, its use seems to be limited to pediatric dentistry. Presented here are few adult cases in which SSC is given with good success.

Outcome and Complications in Surgical Treatment of Lumbar Stenosis or Spondylolisthesis in Geriatric Patients

Development of anesthesiology and improvement of surgical instruments enabled aggressive surgical treatment even in elderly patients, who require more active physical activities than they were in the past. However, there are controversies about the clinical outcome of spinal surgery in elderly patients with spinal stenosis or spondylolisthesis. The purpose of this study is to review the clinical outcome of spinal surgery in elderly patients with spinal stenosis or spondylolisthesis. MEDLINE search on English-language articles was performed. There were 39685 articles from 1967 to 2013 regarding spinal disease, among which 70 dealt with geriatric lumbar surgery. Eighteen out of 70 articles dealt with geriatric lumbar surgery under the diagnosis of spinal stenosis or spondylolisthesis. One was non-randomized prospective, and other seventeen reports were retrospective. One non-randomized prospective and twelve out of seventeen retrospective studies showed that old ages did not affect the clinical outcomes. One non-randomized prospective and ten of seventeen retrospective studies elucidated postoperative complications: some reports showed that postoperative complications increased in elderly patients, whereas the other reports showed that they did not increase. Nevertheless, most complications were minor. There were two retrospective studies regarding the mortality. Mortality which was unrelated to surgical procedure increased, but surgical procedure-related mortality did not increase. Surgery as a treatment option in the elderly patients with the spinal stenosis or spondylolisthesis may be reasonable. However, there is insufficient evidence to make strong recommendations regarding spinal surgery for geriatric patients with spinal stenosis and spondylolisthesis.

Quality of Services in a Tertiary Care Hospital of Northern India: Geriatric Patient Perspective.

This study was planned with the objectives of studying the bio-social and morbidity pattern of elderly and to assess the quality of medical and non-medical services as perceived by elderly patients along with the health worker-patient relation.A Cross-Sectional Descriptive Study was conducted on elderly patients (>60 years) attending outpatient department of a tertiary hospital and residing in Lucknow. Total 242 subjects were selected from the entry gate of outpatient department. Most common morbidity in this age group is hypertension and eye related morbidity in urban area, while in rural area it was musculoskeletal and eye related morbidity. Elderly from Non Peri-urban area mostly perceived that the services rendered were average while majority of those living in Peri-urban area (51.5%) opined that the services rendered were good. Nearly half (44%) of urban elderly patients rated quality of services as average. While among rural elderly patients 42.6% rated quality of services as poor. However those from peri-urban area, 57.1% rated it as poor. Relation of quality of services of hospital with residence of elderly patients was statistically significant (p <0.05).Among elderly of urban area, most frequent morbidity was hypertension. total elderly patient from urban area one third perceived poor quality of services. While elderly patient of rural areas, majority had felt poor quality of service. About 57.1 percent of elderly patient of non peri-urban area had perceived poor quality of service followed by 28.6 percent of very poor quality of services. While of peri-urban area 40.9 percent had felt average quality of services followed by 34.8 percent with poor quality of services.

Morbilidad y mortalidad del paciente geriátrico intervenido de urgencia / Morbidity and mortality in geriatric patients undergoing emergency surgery

Introducción: la elevación de la expectativa de vida de la población se deduce por el aumento de pacientes que se operan en edades superiores a los 60 años, y una gran cantidad lo hace de manera urgente. Objetivo: describir la morbilidad y la mortalidad anestésicas de origen cardiovascular, en el paciente geriátrico intervenido quirúrgicamente de urgencia. Métodos: se realizó un estudio descriptivo, prospectivo y longitudinal de 123 pacientes mayores de 60 años en el Hospital General Docente "Leopoldito Martínez", durante el período comprendido entre enero de 2010 y diciembre de 2011. Los datos fueron recogidos de las historias clínicas y los protocolos de anestesia. Resultados: se presentaron antecedentes patológicos cardiovasculares en 34,1 % de los pacientes y predominó la hipertensión arterial en 15,4 %. El factor de riesgo más frecuente fue el hábito de fumar (26,8 %), y la herniorrafia fue la intervención más practicada en urgencia (33,3 %). El método anestésico más empleado fue la anestesia general, en 68,3 % de los casos, y dentro de ella, la anestesia general orotraqueal. Las complicaciones cardiovasculares fueron más frecuentes y ocurrieron en el período transoperatorio. Fallecieron 5 pacientes (4,1 %) y ninguna muerte fue imputable al proceder anestésico. Conclusiones: la morbilidad anestésica de origen cardiovascular en el paciente geriátrico intervenido quirúrgicamente de urgencia tuvo relación directa con la mortalidad.

Introduction: as a result of the increase in life expectancy, more patients aged over 60 undergo surgery, and a large number of them undergo emergency surgery. Objective: describe anesthetic morbidity and mortality of cardiovascular origin in geriatric patients undergoing emergency surgery. Methods: a prospective longitudinal descriptive study was conducted of 123 patients aged over 60 at Leopoldito Martínez General Teaching Hospital from January 2010 to December 2011. The data were collected from medical records and anesthesia protocols. Results: 34.1 % of the patients had a history of cardiovascular disease, and arterial hypertension was predominant in 15.4 %. Smoking was the most frequent risk factor (26.8 %), and herniorrhaphy was the most common emergency intervention (33.3 %). The anesthetic method most frequently used was general anesthesia (68.3 %), with a predominance of general orotracheal anesthesia. Most cardiovascular complications appeared during the transoperative period. Five patients died (4.1 %), with no death attributable to the anesthetic procedure applied. Conclusions: a direct relationship was found between anesthetic morbidity of cardiovascular origin and mortality in geriatric patients undergoing emergency surgery.

Analysis of Emergency Department Patients Transferred from Geriatric Hospitals: Case Series Descriptive Study

PURPOSE: Nursing homes continue to increase in number, and more residents are being transferred to emergency departments (EDs). The objective of this study was to investigate the overall characteristics of residents who were transferred to the ED and follow-up their course of treatments. METHODS: We identified nursing home residents aged 65 years and older who had been transferred to the ED of a regional tertiary university medical center from January 2008 to December 2009. Further attention was paid to those who had been diagnosed with sepsis. Meantime, a separate cohort of sepsis patients was collected, made up of geriatric patients aged 65 years or older who had visited the ED voluntarily from home or through medical institutions other than nursing homes during the same period. We then compared the two cohorts of sepsis patients. RESULTS: A total of 321 patients aged 65 years or older were transferred from nursing homes during the study period. Their mean age was 77.6+/-7.2 years, and 172 (54.8%) were females. Seventy six (24.2%) patients whose caregivers did not comply with the necessary procedures or refused aggressive management were discharged home or were retransferred to nursing homes. A total of 41 sepsis patients had been transferred from nursing homes, whereas 64 patients had visited the ER voluntarily or through medical institutions other than nursing homes. Even though the difference between the two groups was not significant statistically, patients transferred from nursing homes tended to be discharged or retransferred to nursing homes with inadequate treatment. CONCLUSION: A considerable number of patients transferred from nursing homes were found to be discharged or retransferred to nursing homes during acute care due to refusal of aggressive treatments. Likewise, the comparison of sepsis patients between the two arms showed a greater portion being retransferred with inadequate treatment as well as a greater rate of mortality among patients transferred from nursing homes.

Surgical Treatment of Degenerative Lumbar Spine Disease in Geriatric Patients Over 70 Years Old: A Review of Two Decades

OBJECTIVE: The aim of this study is to evaluate the transition of lumbar spinal treatments for geriatric patients over 70 years old over two decades. METHODS: We retrospectively assessed 730 patients who were 70 years and older and underwent lumbar surgery. We analyzed the number of diseases, operation methods and complications with 5-year intervals from 1987 to 2006. RESULT: The number of patients older than 70 years who underwent lumbar surgery increased according to our analysis of the period spanning from 1987 to 2006. Thirty-two (1%), 77 (1.7%), 232 (4.4%), and 389 (8.2%) patients over 70 years underwent lumbar spine surgeries. Among them, the 8, 29 and 45 patients had one level degenerative spondylolisthesis for the periods 1992-1996, 1997-2001 and 2002-2006. Twenty-four, 29 and 58 patients had lumbar stenosis during all these time periods. Over time, we performed a larger variety of operations as well as more aggressive operations. From January 2002 to December 2006, a total of 308 patients were over 70 years old and had lumbar spine surgeries performed on them. Among them, the ASA class I was 58 (19%), the ASA class II was 213 (69%) and the ASA class III was 37 (12%). During that period, PLIFs and PS fixations were performed on 69 patients. Among them, 8 patients were ASA III. Large numbers of lumbar arthorodesis have been performed in geriatric patients over the age of 70 years in our series. CONCLUSION: The surgical treatment of degenerative spine disease in the elderly patients was increased due to improved surgical technique and advances in medical treatment including anesthesia. The authors suggest that fusion surgery can be done safely in elderly patients even though they have high-grade ASA classification.

Cerebral Infarction following Total Hip Replacement Arthroplasty in Geriatric Patient : A case report / 대한마취과학회지

Perioperative cerebral infarction is uncommon and its mechanism is often uncertain. This is a report of an unusual case of acute cerebral infarction following general anesthesia. The patient was a 83-year-old female admitted for total hip replacement arthroplasty (THRA). There were no previous cerebro- and cardio-vascular symptoms and history. During introduced general anesthesia with sevoflurane, there was a persistent low systolic BP of 80-100 mmHg (preoperative BP was 140/85 mmHg). On emerging from anesthesia, confusion and dense right hemiparesis were observed. Emergency CT brain scan showed early cerebral infarction in the middle cerebral artery (MCA) territory. Even though prompt supportive neurosurgical intensive care was initiated, the patient died at postoperative 4 days.

Evaluation of Minimal Dose of Midazolam for Sedation in Geriatric Spinal Anesthesia / 대한마취과학회지

BACKGROUND: It is stated that spinal anesthesia may alter susceptibility to the soporific effects of sedatives. In the geriatric patients who are susceptible to midazolam, the adequate dosage of midazolam for sedation was evaluated in spinal anesthesia. METHODS: ASA 1 or 2 50 elderly patients (over 65 years old) who were scheduled for lower abdominal or extremities operations, were randomly assigned into two groups. Midazolam 0.01 mg/kg was administered every 5 minutes until becoming sedated before general anesthesia in the control group, while 0.01 mg/kg was administered every 5 minutes after stabilized for 15 minutes after spinal anesthesia in the study group. RESULTS: It took 15 +/- 5.0 minutes for the control group to fall asleep while the spinal anesthesia group showed significantly less time with 11 +/- 4.2 minutes. The total amount of midazolam administered were 1.5 +/- 0.6 mg in the control group and 1.2 +/- 0.5 mg in the study group, which showed no significance. However, the amount of midazolam compared with the body weight revealed 0.031 mg in the control group and 0.023 mg in the spinal anesthesia group suggesting significantly decreased dosage in the study group. CONCLUSIONS: Midazolam revealed significant sensitivity as well as sedative susceptibility in the elderly patients who underwent spinal anesthesia. Therefore, the dosage titration of midazolam for the elderly patients in spinal anesthesia should be carefully considered.

Pathogens Isolated from Geriatric Inpatients with Urinary Tract Infections:Their Composition and Drug Resistance Analysis / 中华医院感染学杂志

OBJECTIVE To retrospectively analyze the results of the composition and drug resistance of urinary pathogens isolated from geriatric inpatients from 2003 to 2005.METHODS The identification and antibacterial drug sensitivity test of urinary pathogens was carried out by VITEK AMS-60.RESULTS Urinary tract infections of geriatric inpatients were still mostly caused by Gram-negative bacilli(72.9%),others as Gram-positive cocci(14.3%) and fungi(12.8%).The majority of Gram-negative bacilli was Escherichia coli(46.6%) and the majority of fungi was Candida albicans(7.9%),as for Grampositive cocci,were Enterococcus faecalis(5.3%) and coagulase negative Staphylococcus(4.9%).Drug resistance rate of common antibiotic against the majority of urinary pathogens showed an ascending trend.CONCLUSIONS E.coli is still the primary urinary pathogen among geriatric inpatients,but the isolation of fungi and multi-drug-resistant bacteria is on the rise.

Nutritional Status of Hospitalized Geriatric Patients Using by the Mini Nutritional Assessment / 대한지역사회영양학회지

The prevalence of undernutrition in hospital populations is known to be high. The presence of malnutrition is associated with depression, infections, sarcopaenia, falls, fractures, reduced autonomy and increased mortality. This study specifically examined the prevalence of malnutrition in patients aged 65 or older at the time of admission as determined by the Mini Nutritional Assessment (MNA) which has been a frequently used nutritional risk screening tools in detecting undernutrition in old people. This study was done for one hundred eight hospitalized geriatric patients in Seoul National University Bundang Hospital, Seoul, Korea. On admission baseline history, anthropometrics measurements, laboratory data and nutritional status by MNA were assessed. Length of hospital stay was obtained by reviewing medical charts. We used one-way analysis of variance to compare the differences in variables. Spearman's rank correlation coefficients were calculated for associations between MNA and variables. On admission, 22.3% of patients were malnourished and 40.7% were at risk of malnutrition according to the MNA. Percent of ideal body weight, anthropometrics data, albumin, and hemoglobin were lower in the malnourished patients (p < 0.05). The malnourished patients stayed in the hospital 7.3 days longer, as compared with well nourished patients (p < 0.05). Percent of ideal body weight, albumin, hemoglobin and total cholesterol were correlated inversely with nutritional status according to MNA (p < 0.05). MNA can be used for nutritional assessment in Korean old people, because MNA significantly correlated with other nutritional assessment parameters, such as, anthropometric and laboratory data in hospitalized geriatric patients. The high prevalence of malnutrition in the elderly was observed and the presence of malnutrition on admission predicted a significant increase in the length of hospital stay in this study. Therefore further studies are needed to determine whether nutritional interventions in old people with low MNA scores can improve clinical outcomes during the hospital course.

Performance evaluation of rocuronium target-controlled infusion system in geriatric patients / 中国微创外科杂志

Objective To determine the difference between the measured(Cm) and the target rocuronium plasma concentration(Cp) in geriatric patients given by target-controlled infusion(TCI) during laparoscopic rectectomy or colectomy,and to evaluate the performance of the rocuronium TCI system(Szenohradszkay model).Methods Twenty-four ASA I～II patients aged 65～81 years old received selective laparoscopic rectectomy or colectomy.After induction,all patients received rocuronium by TCI system.The beginning Cp was 1000 ng/ml,then increased to 1300,1600,1900,2200,and 2500 ng/ml,according to the neuromuscular transmission response.The endpoint of Cp was determined when the T1 was maintained at 5%～10%.Radial arterial blood samples were taken before anesthesia and before the adjustment of Cp each time,to determine the plasma concentration of rocuronium by using HPLC/MS.We used parameters of bias,precision,and wobble to evaluate the performance of the TCI system. Results The endpoint Cp(when the T1 was maintained at 5%～10%) was 1600 ng/ml in 2 patients,1900 ng/ml in 5 patients,2200 ng/ml in 9 patients,and 2500 ng/ml in 8 patients.The bias,precision,and wolbble of the rocuronium TCI system were 4.69%,14.93%,and 17.24%,respectively. Conclusions The rocuronium TCI system with Szenohradszkay pharmacokinetic model is clinically acceptable for Chinese geriatric patients.

The Effect of Intravenous Midazolam or Atropine on Spinal Anesthesia-Induced Hypothermia in Geriatric Patients / 대한마취과학회지

BACKGROUND:Perioperative hypothermia causes several complications, and in particular, is more hazardous in elderly patients. Hypothermia during regional anesthesia is often ignored. We investigated the effect of IV midazolam or atropine premedication on core hypothermia in geriatric patients undergoing transurethral procedures via spinal anesthesia. METHODS: Forty-five elderly (65-92 years old), ASA I or II patients about to undergo transurethral procedures, such as prostate or bladder tumor removal were enrolled into this study. In all cases, standard spinal anesthesia was administered. The control group received no premedication, the midazolam group 0.02 mg/kg of midazolam, and the atropine group 5microgram/kg of atropine, respectively just before spinal anesthesia. Core temperature was measured at the right tympanic membrane before anesthesia, at 10 and 30 min later, at the end of anesthesia, and 30 min after recovery from anesthesia. RESULTS: Reduction of core temperature from the basal value, after 10 and 30 min of anesthesia, at the end of anesthesia, at 30 min after anesthesia during post-operative care unit in the control group were 0.31, 0.61, 0.5, and 0.42 degrees C, respectively; 0.41, 0.61, 0.9, 0.65 degrees C in the midazolam group; and 0.15, 0.29, 0.37, 0.47 degrees C in the atropine group. When compared with no premedication, midazolam administration was associated with a significantly lower core temperature at the end of anesthesia. Atropine administration was associated with a significantly higher core temperature than the midazolam group after 10 and 30 min of anesthesia, and at the end of anesthesia, and the untreated control group after 10 and 30 min of anesthesia. CONCLUSIONS: IV premedicant midazolam decreased core temperature; however, atropine administration significantly reduced the magnitude of hypothermia associated with spinal anesthesia in geriatric patients.

The effects of combination of parenteral and enteral nutrition on prognosis of severe craniocerebral injury of geriatric patient / 肠外与肠内营养

Objective:To study the effects of combination of parenteral and enteral nutrition in sequence on prognosis of severe craniocerebral injury of geriatric patient.Methods:The method and effects of nutrition support have been studied in 84 cases of severe craniocerebral injury of geriatric patient.The patients of study group were fed by parenteral and enteral nutrition in sequence in early period,and the patients of the control group were nutritionally supported with common method for 6-7 days.Results:Nitrogen cumultive balances,nutitional index of the study group were signficantly better than that of the control group(P