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Aim: The aim of the study was to evaluate the comparative effect of Ornigreat gel and Hexigel as a local drug delivery system in association with scaling and root planing (SRP) in patients with chronic periodontitis. Materials and Methods: A double-blind trial was conducted to test the comparative efficacy of the two commercially available Ornigreat gel and Hexigel at Indira Gandhi Govt. Dental College and Hospital, Jammu. These indices were recorded at baseline (“0 day”), 15th day, 30th day, 60th day, and 90th day in 40 sites, >4 mm pockets in 11 patients among which 20 sites received Ornigreat gel and other 20 sites receive Hexigel following SRP were compared. Results: The results of the study showed that the combination of SRP and Ornigreat gel therapy was more effective in reducing the mean values of gingival index and sulcus bleeding index though not statistically significant, but the values of plaque index showed statistical significance on the 60th day and 90th day, and the probing pocket depths showed statistically significant difference from the 15th day to the 90th day at P < 0.05 in comparison with Hexigel. Conclusion: The Ornigreat gel could be an efficient local drug delivery system when used in adjunct to SRP in comparison with Hexigel.
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Objective @#To investigate the short-term efficacy of implant in the treatment of patients with dentition defect caused by chronic periodontitis. @*Methods @#53 patients with mild to moderate chronic periodontitis treated in our hospital from June 2014 to May 2015 were selected as observation group, and 53 patients without periodontal diseases in the same period were selected as control group. The plaque index (PLI), sulcus bleeding index (SBI), periodontal probing depth (PD) and gingival papilla index (PIS) were measured at six months and one year after operation, respectively. Interleukin-6 (IL-6), interleukin-8 (IL-8), high sensitive C-reactive protein (hs-CRP) and tumor necrosis factor-α (TNF-α) were detected at six months and one year after operation, respectively. At the last follow-up, the survival rate of two groups were calculated.@*Results @#One year after operation, 5 of the 64 implants in the observation group failed compared with 2 of the 71 implants in the control group. There was no statistical difference in the implant survival rate between the two groups (92.19% vs 97.18%, P=0.191). There was no significant difference in SBI (t=0.936, P=0.351)、 PLI (t=0.457, P=0.649)、PIS (t=1.132, P=0.217)、PD (t=0.957, P=0.341) between the two groups at six months after operation. One year after operation, the periodontal index of the observation group was higher than that of the control group SBI (t=5.297, P=0.000)、 PLI (t=2.341, P=0.021)、 PIS (t=8.218, P=0.000) and PD (t=6.492, P=0.000). The levels of IL-6 (t=6.463, P=0.000)、 IL-8 (t=7.202, P=0.000)、 hs-CRP (t=4.237, P=0.000) and TNF-α (t=6.194, P=0.000) in the observation group were higher than those in the control group at six months after operation. One year after operation, the level of inflammatory factors in the observation group was higher than that in the control group IL-6 (t=12.835, P=0.000)、 IL-8 (t=13.207, P=0.000)、 hs-CRP (t=11.319, P=0.000) and TNF-α (t=8.117, P=0.000). @*Conclusion @# Implant as the treatment of patients with dentition defect caused by chronic periodontitis obtained satisfied short-term effect, but its long-term efficacy remains to be further verified.
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10.3969/j.issn.2095-4344.2013.25.022
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INTRODUÇÃO: na análise da teoria da pressão/tensão do movimento dentário, a aplicação de uma força ortodôntica causa um deslocamento gradual dos fluidos do ligamento periodontal, acompanhado pela distorção das células e da matriz extracelular. OBJETIVOS: avaliar a quantidade de volume do fluido gengival (FG) nas faces mesiais e distais dos caninos superiores, de 14 pacientes (3 homens e 11 mulheres) submetidos a movimentação ortodôntica. MÉTODOS: o fluido foi coletado com tira de papel absorvente padrão (Periopaper®) e seu volume foi determinado por meio da utilização do medidor Periotron®, em sete tempos distintos (dia -7, dia 0, 1 hora, 24 horas, 14 dias, 21 dias e 80 dias). O teste Friedman foi usado para comparar os dados obtidos (p < 0,01 e p < 0,05). RESULTADOS: os resultados mostraram que houve uma alteração significativa do volume de FG ao longo do tempo, tanto no lado de pressão (p < 0,001) quanto no lado de tensão (p < 0,01). No lado de pressão, o volume de FG foi significativamente menor nos tempos 0 (p < 0,01) e 24h (p < 0,001), comparados com o tempo 80d.
INTRODUCTION: In the analysis of the pressure-tension theory of tooth movement, the application of an orthodontic force causes gradual displacement of fluids of the periodontal ligament, followed by distortion of the cells and extracellular matrix. OBJECTIVES: This study evaluated the gingival fluid volume on the mesial and distal aspects of the maxillary canines of 14 patients (3 males and 11 females) submitted to orthodontic movement. METHODS: The fluid was collected using standard absorbent paper strips (PeriopaperÕ) and the fluid volume was determined using the instrument PeriotronÕ at seven different periods (day -7, day 0, 1 hour, 24 hours, 14 days, 21 days, 80 days). The Friedman test was applied to compare the data achieved (p < 0.01 and p < 0.05). RESULTS: The results revealed a significant change in the gingival fluid volume with time on both the pressure side (p < 0.001) and the tension side (p < 0.01). On the pressure side, the gingival fluid volume was significantly lower at the periods 0 (p < 0.01) and 24hs (p < 0.001) compared to the period 80 days.
Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Cuspid , Gingiva/abnormalities , Inflammation , Tooth Movement Techniques , Periodontal DiseasesABSTRACT