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1.
Univ. med ; 53(1): 94-102, ene.-mar. 2012. ilus
Article in Spanish | LILACS | ID: lil-665444

ABSTRACT

Se presenta el caso de una mujer de 30 años, que presentaba síntomas respiratorios y constitucionales de dos meses de evolución. Se documentó exudado linfocitario y proteinuria, y se descartó tuberculosis y neoplasia maligna. Se le practicó biopsia pleuraly de ganglio linfático, que reportaron sarcoidosis. Se tomó biopsia renal por presencia de proteinuria con pruebas serológicas negativas, y se encontró glomerulonefritis membranosa secundaria. Se inició tratamiento con prednisolona...


We describe the case of a 30 years old female with a two month history of respiratory symptoms and malaise. A lymphocytic pleural effusion and proteinuria were documented,tuberculosis and malignancy were ruled out. Biopsy of lymph nodes and pleura confirmed sarcoidosis. Due to non-nephrotic proteinuria with negative serology tests, kidney biopsy was performed, showing secondary membranous glomerulonephritis. Treatment with prednisolone was started...


Subject(s)
Glomerulonephritis , Kidney/injuries , Sarcoidosis/history , Sarcoidosis/prevention & control
2.
Rev. salud bosque ; 1(1): 47-53, 2011. tab, ilus
Article in Spanish | LILACS | ID: lil-779440

ABSTRACT

Las alteraciones renales producidas por el uso crónico de analgésicos antiinflamatorios no esteroideos (AINE) son diversas, la principal corresponde a nefropatía tubulointersticial que resulta en la necrosis papilar renal. También se han reportado casos de síndrome nefrótico con biopsias que revelan enfermedad de cambios mínimos y muy excepcionalmente una glomerulonefritis membranosa, la cual desaparece al suspender el medicamento. Se presenta el caso de una paciente remitida al Servicio de Nefrología del Hospital Militar Central (HMC) de Bogotá por presentar elevación de los azoados durante una valoración prequirúrgica. Sin evidencia de causa secundaria y después de ser estudiada fue llevada a biopsia renal, encontrando una nefropatía membranosa y como único antecedente el uso crónico de AINE.


The renal effects caused by chronic use of non-steroidal anti-inflammatory drugs (NSAIDs) are diverse; the main corresponds to tubulointerstitial nephropathy resulting in renal papillary necrosis. There have also been reported cases of nephrotic syndrome with biopsy that revealed minimal change disease and exceptionally membranous glomerulonephritis, which resolves after discontinuation of medication. There is a report of a case in Bogota in which a patient was referred to the Nephrology Service of the Central Military Hospital due to elevation of nitrogen compounds during preoperative assessment. No evidence of secondary cause was present and after being studied, a renal biopsy was carried out, membranous nephropathy located; the only positive finding in the past medical history is the chronic use of NSAIDs.


Subject(s)
Humans , Female , Middle Aged , Anti-Inflammatory Agents, Non-Steroidal , Glomerulonephritis, Membranous , Colombia
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