ABSTRACT
Objective:To compare the results of three kinds of glucometers and automatic biochemistry analyzer for the detection of blood glucose level of finger capillary and vein blood, and adopt linear regression to analyze their relationship.Methods: 204 patients with or without diabetes were enrolled in this study. Their finger capillary and vein blood were detected by three kinds of glucose meters and automatic biochemistry analyzer, respectively. And these data were analyzed by using linear regression and pair-t-test.Results: The comparative results revealed that the order of correlation between every glucose meters with automatic biochemistry analyzer was Accuchek higher than GT-1920 and GT-1920 higher than One Touch when the range of hematocrit (Hct) value was in 35.1%-51.6%. The correlation of Hct between every glucose meter and automatic biochemistry analyzer when the range of Hct was 25.0%-35.0% was significant higher than that when the range was 35.1%-51.6% (t=2.19,P<0.05). For finger capillary blood, the bias of One Touch was largest, while for vein blood, the bias of GT-1920 and One Touch were better. Besides, the detected results of blood glucose both of GT-1920 and One Touch were significantly higher than automatic biochemistry analyzer(t=2.34,P<0.05).Conclusion: There were better correlation between every glucose meter and automatic biochemistry analyzer, respectively, and the correlations between them can be effected by Hct. While there were still certainly difference between them.
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Objective:To assess the accuracy of the portable blood glucose meters. Methods:The study design was equivalent clinical trial. The participants were selected according to the inclusion and exclusion criteria from inpatients, outpatients and outpatient volunteers of the department of endocrinology. The fingertip blood glucose was measured by five portable blood glucose meters and compared with vein blood glucose measured by biochemistry. The measurement error was assessed by the mean difference with biochemical results. The correlation coefficient was calculated to test the correlation between fingertip and vein blood glucose. Results:there were 230 cases in total including 86 males and 144females. The average age was (50.6±13.5) years old. There were 73 fasting blood glucose and 157 postprandial blood glucose. The range of biochemical blood glucose value was from 2.19 to 19.95 mmol/L and the averaged biochemical blood glucose concentration was (6.77±2.65) mmol/L. The minimum measurement error was 0.08mmol/L measured by blood glucose meter C. However, there was one meter E whose 95%confidence interval of measurement error exceeds the equivalent interval (-0.83, 0.83) mmol/L range and the difference does not meet the clinical equivalence. The measurement bias was all lower than 95%. Conclusion:The blood glucose meters can be used as the day-to-day monitoring of blood glucose in patients. The accuracy needs to be improved and continuously monitored.
ABSTRACT
Objective To evaluate the precision of BREEZE~(TM) glucose monitor and correlation of glucose measurements between fingertip capillary whole blood glucose(CBG)using BREEZE~(TM) glucose monitor and venous plasma glucose(VPG)using autoanalyzer.Methods All samples of venous plasma and fingertip blood from 188 diabetes or non-diabetes patients were detected for glucose level at fasting,30,60 and 120 min postprandial.BREEZE~(TM) glucose monitor and autoanalyzer measured CBG and VPG respectively.Intra-and inter- coefficients of variations were determined using 10 BREEZE~(TM) glucose monitors with normal,slight high and high glucose levels for the three lots of strips.Results The correlation coefficients between CBG and VPG were all higher than 0.950 at fasting and different postprandial time.98.94% of all measurements were in the A zone when using error-grid analysis.The relevant differences between CBG and VPG were less than 5% at different blood glucose concentrations.The intra-and inter-coefficients of variations of blood glucose values at different blood glucose concentrations using different lots of strips were within 5%.Conclusion BREEZE~(TM) glucose monitor provides high accurate and precise glucose readings on fasting and different postprandial time points over a variety of blood glucose concentrations.