ABSTRACT
We evaluated the clinical efficacy of Goshajinkigan in patients complaining of lower urinary tract symptoms (LUTS). A total of 109 patients (86 males and 23 females) who were orally administered Goshajinkigan at a dose of 5 to 7.5g/day for 4 to 8 weeks, were studied retrospectively. Improvements of symptoms were confirmed in 50 patients. Multivariate analysis showed the response rates were significantly higher among patients with urgency, residual feeling, myocardial ischemia and brain infarction respectively, and were significantly lower among patients with hesitancy. Our findings suggest that Gosha jinki-gan mainly improves urgency and/or residual feeling of lower urinary tract symptoms, and that these symptoms are the main LUTS associated with jinkyo.