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Background: Taken care therapeutics of breast cancer is in constant evolution. She links, according to the stadium of illness, a specific treatment of the cancer and mammary reconstruction which makes integral part of the treatment of breast cancer today. The lipofilling or lipostructure is one of the techniques used in mammary reconstruction.Methods: A descriptive retrospective study on lipofilling accomplished in Hospital complex of Dax, France from January 1st, 2016 till October 31st, 2017 was accomplished, to assess the rate of aesthetic and psychological satisfaction of the patients on the basis of breast Q, then to assess its effectiveness and its security. The statistical analysis was made with the software Excel of Microsoft Office 2007.Results: Authors could record 52 lipofillings at 40 patients among 1212 gynecological surgical operations is 4.29% surgical activities. 47 cases (90.38%) of lipofilling were accomplished at 35 patients after a surgery for breast cancer accomplishing a frequency of 3.87% of surgical activity. The women from 49 to 54 years old are the most concerned the median age of which was of 52 years (37 and 73 years) and the patients are still sexually active in 26 cases (74.29%). The mastectomy was practiced in 32 cases (91.45%). An immediate reconstruction was accomplished at 29 (82.86%) patients. The back big rag autologous was used in 22 cases (62.85%). In 33 cases (94.27%), the lipofilling was accomplished to supplement the reconstruction among which by the back big rag at 22 patients (62.5%) and by mammary prosthesis at 11 patients (31.42%). One took a sample in 32 cases of a volume from 400 to 700 ml of grease average of which was 456.38 ml (200-800 ml). A volume from 200 to 300 ml was injected at 17 patients (36.17%) with an average of 264.14 ml (100-600 ml). No repetition of the cancer was recorded during this study. A score of more than 60 was recorded in every domain for the valuation of satisfaction in more than 90% cases.Conclusions: With the evolution of the taking care of the cancers of breast, mammary reconstruction by lipofilling is a technology which goes know a big development. It is a new way of natural reconstruction at the mastectomy patients who wish, more and more a less aggressive surgical gesture with good result.
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Objective: To observe the changes of dysfunctional high density lipoprotein cholesterol (dyHDL) and the intervention effect of Xiangsha Liu Junzitang in rats with spleen deficiency and hyperlipidemia, and reveal the effect and mechanism of Xiangsha Liu Junzitang on dyHDL in rats with spleen-deficiency hyperlipidemia. Method: Seventy-five SPF SD rats were randomly divided into normal group, high fat group, spleen deficiency and high fat group, Xiangsha Liu Junzitang low and high dose groups (5.67, 11.34 g·kg-1). In the spleen deficiency and high fat group, as well as Xiangsha Liu Junzitang low and high dose groups, composite method of improper diet and exhaustive swimming was used for 15 days for modeling. After modeling for 15 days, normal group was fed with basic diet, while the high-fat group, spleen-deficiency and high-fat group, the Xiangsha Liu Junzitang low and high dose groups were fed with high-fat diet. After 12 weeks, the Xiangsha Liu Junzitang low dose and high dose groups received corresponding dosage of drugs, while normal group, high fat group and spleen deficiency high fat group received corresponding volume of normal saline. After 4 weeks, the contents of total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol cholesterol (LDL-C), and high density lipoprotein cholesterol(HDL-C)were detected by automatic biochemistry analyzer, while D-xylose excretion rate was measured by phloroglucinol method. The morphological changes of liver cells were observed by hematoxylin eosin (HE) staining. The level of PON1, apoA1 and SAA in plasma were detected by enzyme-linked immunosorbent assay (ELISA). Paraoxonase 1(PON1), apolipoprotein A1 (apoA1) and serum amyloid protein A (SAA) gene expression in rats liver were detected by Real-time fluorescence quantitative polymerase chain reaction (Real-time PCR). Result: As compared with normal group, the serum TC, TG, and LDL-C levels were significantly increased in the high-fat group and spleen-deficiency high-fat group (PPPPPPD-xylose excretion rate was significantly decreased in the spleen-deficiency and high-fat group (PPPPPPPPConclusion: The lipid disorder in hyperlipidemia rats was aggravated by the spleen deficiency, but was corrected after intervention with Xiangsha Liu Junzitang. and its mechanism may be related to the regulation of the expression of dyHDL-related genes and protein.
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Abstract: Introduction: Young people who start the university life face a key stage for the acquisition of habits and lifestyles. The test Course Navette is one of the most used worldwide because of its easy measurement, validity, effectiveness and sensitivity in different age ranks. Material and methods: An observational, descriptive and transversal study with quantitative approach; with 100 students participating (43 men and 57 women) with an average age of 21.06 ± 2.43 at the University of Santander, Cúcuta. For the development of this research, were obtained measurements anthropometric, hematological, physiological and performance on an empty stomach Leger test. Results: 62% of participants had a BMI of normal weight, 24% overweight and obesity and underweight was 8 and 6% respectively. In turn 32% of men and 17.5% of women have high cardiovascular risk according to abdominal circumference. VO2max. in the Leger test was 32.92 ± 7.12 to 533.80 ± 371.34 meters traveled. Regarding glycemia before the test was 80.99 ± 11.91 and after 105.59 ± 20.89. Conclusion: No significant differences in fat percentage were found (p = 0,863), muscle (p = 0,740) and water (p = 0,804) after Leger test. However, there were significant changes in FC, TAS, TAD, red cells, white cells, hemoglobin, platelets and blood glucose levels (p = 0,000). Regarding the VO2max. (p = 0,597) and travel meters (p = 0,619) no differences were found by gender.
Resumen: Introducción: Los jóvenes que inician la vida universitaria enfrentan una etapa clave y vital para la adquisición de hábitos y estilos de vida. El test de Course Navette es uno de los test más utilizados a nivel mundial, debido a su fácil medición, validez, efectividad y sensibilidad en diferentes rangos de edad. Material y métodos: Un estudio observacional, descriptivo y transversal con enfoque cuantitativo; en el que participaron 100 estudiantes (43 hombres y 57 mujeres) con una edad promedio de 21.06 ± 2.43 de la Universidad de Santander, Cúcuta. Para el desarrollo de esta investigación, se obtuvieron medidas antropométricas, hematológicas, fisiológicas y realización del test de Leger en ayunas. Resultados: El 62% de los participantes tuvieron un índice de masa corporal (IMC) de normopeso, el 24% sobrepeso y para obesidad e infrapeso fue 8 y 6% respectivamente. A su vez el 32% de los hombres y el 17.5% de las mujeres tienen alto riesgo cardiovascular según medidas de circunferencia abdominal. El VO2máx. en el test de Leger fue de 32.92 ± 7.12 con 533.80 ± 371.34 metros recorridos. Respecto a la glucemia antes del test fue de 80.99 ± 11.91 y después 105.59 ± 20.89. Conclusión: No se encontraron diferencias significativas en el porcentaje graso (p = 0,863), muscular (p = 0,740) y agua (p = 0,804) después del test de Leger. No obstante, hubo cambios significativos en la FC, TAS, TAD, glóbulos rojos, blancos, linfocitos, hemoglobina, plaquetas y glucemia (p=0,000). Respecto al VO2máx. (p = 0,597) y metros recorridos (p = 0,619) no se encontraron diferencias según género.
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RESUMO: O uso de biomassa fúngica como biocatalisadora lipásica representa uma atraente abordagem para o tratamento de águas residuais oleosas e produção de biodiesel, a partir de óleos e graxas residuais, devido à sua maior estabilidade, possibilidade de reuso e baixo custo. Neste trabalho foram obtidos cem isolados de fungos, a partir de escumas de caixa de gordura e esgoto, solo e tecidos necrosados de plantas e insetos, que foram avaliados quanto ao crescimento e à atividade lipásica, no meio de cultura básico, para atividade lipásica extracelular, e meio mineral mínimo + óleo de soja + rodamina, para atividade lipásica intracelular, com resposta positiva e diferenciada de 66 deles, inclusos como pertencentes aos gêneros Aspergillus , Beauveria , Botrytis , Cladosporium , Colletotrichum , Fusarium , Geotrichum , Penicillium , Rhizomucor e Verticillium . Na sequência, o potencial hidrolítico dos isolados Penicillium sp. F002 e Rhizomucor sp. F018 foi avaliado sobre óleo de soja comestível e escuma de caixa de gordura, em fermentação em estado sólido, através da quantificação das variáveis: produção de CO2, remoção do teor de óleos e graxas e crescimento da biomassa. Os resultados confirmaram a elevada atividade lipásica extracelular de Penicillium sp. F002 e a elevada atividade lipásica intracelular de Rhizomucor sp. F018. Portanto, o isolado Rhizomucor sp. F018 mostrou potencial para utilização em pesquisas futuras, na forma de células integrais lipásicas, para o tratamento de águas residuais oleosas e como biocatalisador na produção de biodiesel a partir de resíduos oleosos.
ABSTRACT: The use of fungal biomass as a lipase biocatalyst represents an attractive approach for the treatment of oil wastewater and production of biodiesel from oil and residual grease, due to its greater stability, possibility of reuse, and lower cost. In this work, a hundred filamentous fungi were isolated from grease trap and sewage scums, soil, and necrotized plants and insects tissues. The isolates were assessed for growth and lipase activity in the culture basic medium, for extracellular lipase activity, and mineral medium minimum + soybean oil + rhodamine, for intracellular lipase activity, with positive and differential response of 66 of them, including those belonging to the genera Aspergillus , Beauveria , Botrytis , Cladosporium , Colletotrichum , Fusarium , Geotrichum , Penicillium , Rhizomucor , and Verticillium . Following, previously selected Penicillium sp F002 and Rhizomucor sp. F018 isolates were evaluated in solid-state fermentation, for the hydrolytic potential on edible soybean oil and grease trap scum, quantified by: CO2 production, removal of the content of oils and greases, and biomass growth. Results confirmed the high extracellular lipase-activity of Penicillium sp. F002 and the high intracellular lipase activity of Rhizomucor sp. F018. Therefore, the isolated Rhizomucor sp. ECG18 showed potential for use in future research, in the form of whole-cell lipases, for oily wastewater treatment, and as a biocatalyst in the production of biodiesel from oil residues.
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Aims: The aim of this study was to investigate the biodegradation capacity of selected indigenous fungal isolates and optimization of their degradation ability using various environmental factors such as pH, incubation temperature, nutrient concentration and inoculums size in reducing pollution effect of palm oil mill effluent (POME) in the environment. Place and Duration of Study: Two fungal isolates Candida rugosa and Geotrichum candidum used in this work were previously isolated from POME sample collected from Starline palm oil mill industries, Umukalika, Obingwa LGA, Abia state Nigeria in previous work of authors. The study was carried out from March to August, 2013. Methodology: Spore suspension was prepared by adding 10 ml of 0.1% Tween 80 onto PDA slant of 5 days old culture of Candida rugosa and Geotrichum candidum respectively. Biodegradation of POME was carried out by inoculating 0.1ml (106spores/ml) of respective fungal isolates into different 500 ml Erlenmeyer flasks containing 100ml each of raw POME. They were incubated at 30ºC on a rotary shaker (200rpm). Samples were taken every 24hrs for 144hrs to determine BOD, COD, oil & grease. Similarly, optimization of biodegradation was carried out by studying the effect of different environmental conditions such as different initial pH levels (4.0-8.0), incubation temperature (25-50ºC), concentrations of soy bean (1.5-4.5% w/v) and inoculum size (0.1-0.5 v/v). The experiments were done in triplicates. Results: Biodegradation studies with selected indigenous fungi showed that C. rugosa was able to remove (44.6%) BOD, (13.9%) COD , (50.7%) oil and grease (O&G) while G. candidum reduced BOD, COD, O&G by 46.9%,16.9% and 64,9% respectively after 144hrs. Optimization of degradation in POME using various environmental and nutrients conditions revealed that at pH 8, C. rugosa showed best degradation of COD (48.6%), BOD (74.5%), O&G (41.8%) removal while COD (59.1%), BOD (75.7%) , O&G (59.1%) removal was observed with G. candidum treatment. The optimal incubation temperature for degradation using each of fugal isolates was at 35ºC with 85.2% BOD , 71.8% COD and 67.3% O&G removal for C. rugosa , 87.3% BOD and 63.4% COD for G. candidum .The best degradation ability for C. rugosa and G. candidum were demonstrated at 3.5w/v and 2.5w/v soybean concentrations respectively. The result also showed that increase in inoculum size could not completely reduce oil and grease during degradation process possibly because no single culture supports degradation optimally due to presence of complex sugars Conclusion: The selected fungal isolates exhibited high efficiency for removal of oil and grease as well as organic matter from POME but required control of environmental conditions and nutrient expansion for the effective biodegradation of POME.
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The objective of this experiment was to measure the effects of soybean oil (SBO) and choice white grease (CWG) on apparent ileal digestibility (AID) of amino acids (AA) in corn-soybean meal-distillers dried grains with solubles-based diets fed to growing pigs. Three diets were prepared. The control diet contained corn, soybean meal, distillers dried grains with solubles (DDGS), cornstarch, and no additional fat. Two additional diets were formulated by adding 5% SBO or 5% CWG to the control diet at the expense of cornstarch. Twelve growing barrows with initial body weight of 37.6 kg (standard deviation = 3.22) were equipped with a T-cannula at the end of the ileum and they were allotted to one of three dietary treatments during six experimental periods.The AID of indispensable AA (e.g., arginine, histidine, isoleucine, leucine, phenylalanine, and valine) and dispensable AA (e.g., alanine, aspartic acid, cysteine, and proline) was improved (p<0.10) by the addition of 5% SBO or 5% CWG in the diets. The addition of SBO or CWG improved the AID of AA in a commercial-type diet containing corn, soybean meal, and distillers dried grains with solubles, and the extent of improvement in the AID of AA was comparable between the two sources of dietary fat.
El objetivo de este experimento fue medir el efecto del aceite de soya (SBO) y la grasa blanca (grasa de cerdo, CWG) sobre la digestibilidad ileal aparente (DIA) de aminoácidos (AA) en dietas maíz-soya adicionadas con derivados solubles de destilería para cerdos en crecimiento. Tres dietas fueron preparadas. La dieta control contenía maíz, harina de soya, granos secos de destilería con solubles (DDGS), almidón de maíz, y sin grasa adicionada. Dos dietas adicionales fueron formuladas adicionando 5% de SBO o de GTC a la dieta control, a expensas de la fécula de maíz. Doce cerdos machos castrados, con peso inicial de 37.6 kg (desviación estándar =3.22), fueron equipados con una cánula en T en el extremo del íleo y fueron asignados a uno de los tres tratamientos dietarios durante seis periodos experimentales. La DIA de AA esenciales (por ejemplo, arginina, histidina, isoleucina, leucina, fenilalanina y valina) y no esenciales (por ejemplo, alanina, ácido aspártico, cisteína y prolina) se mejoró (p<0.10) mediante la adición de 5% SBO o de 5% de CWG. La adición de SBO o CWG mejoró la DIA de AA en la dieta, y su nivel de mejoría fue similar entre las dos fuentes de grasa.
O objectivo deste experimento foi avaliar o efeito do óleo de soja (SBO) e gordura branca (de suino, CWG) sobre a digestibilidade ileal aparente (AID) de aminoácidos (AA) em dietas com adição de derivados de milho-soja solúvel de destilaria para suínos em crescimento. Três dietas foram preparadas. A dieta controle continha milho, farelo de soja, grãos secos de destilaria com solúveis (DDGS), amido de milho, e não tinha gordura adicionada. As outras duas dietas tinham uma adição de 5% SBO e a outra com 5% de GTC à custa de amido de milho. Doze suínos machos castrados, com peso inicial de 37.6 kg (DP = 3.22) foram equipados com uma cânula T no final do íleo. O núcleo do AA (por exemplo, arginina, histidina, isoleucina, leucina, fenilalanina e valina) e não-essenciais (por exemplo, alanina, ácido aspártico, cisteína e prolina) foi melhorada (p<0.10) pela adição de 5% SBO CWG ou 5%. A adição de SBO ou CWG melhorou de AA na dieta e o nível de melhora foi semelhante entre as duas fontes de gordura.
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Taking example of treatment to 2 cases of large deep burn, it analyses the experience of treating large deep burn from 4 points: reasonable choice of wound dealing, preventing wound infection by correctly replacing drugs, clinical application of SD-Ag paste, and synthetic judgment of wound infection.
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Objective: To observe the curative and side effects on malignant pleural effusion treated with Ya Dan Zhi's grease (YDZ) and DDP by injecting chest. Methods:Patients were divided into 3 groups randomly: treatment group (24 patients of MPE, injected to chest with DDP60mg and YDZ80mL once every week)、YDZ group (25 patients)、DDP group (23 patients), observing the effects、strength improvement and the side effects.Results: The toltal effective rates in the treatment group was 88.33% and YDZ group 56%、DDP group 56.52% respectively ( P