ABSTRACT
Objective:To explore the medication law of TCM in the treatment of superficial vein thrombosis (SVT) using data mining.Methods:Literature about TCM in the treatment of SVT was retrieved from CNKI, Wanfang Data, and VIP from the establishment of the databases to November 27th, 2022. WPS 12.1.0.15990 was used to conduct statistical analysis on drug frequency, property and taste and meridian. The association rules and systematic clustering were carried out by SPSS Modeler 18.0 and SPSS Statistics 25.0. Finally the medication law of TCM in the treatment of SVT was summarized and refined.Results:A total of 281 articles were included, including 245 internal prescriptions with 182 kinds of Chinese materia medica, and 123 external prescriptions with 188 kinds of Chinese materia medica. The high frequency used oral Chinese materia medica were mainly Angelicae Sinensis Radix, Paeoniae Radix Rubra, Cyathulae Radix, while the high frequency drugs used externally mainly included Rhei Radix et Rhizoma, Phellodendri Chinensis Cortex, Carthami Flos. These Chinese materia medica were mainly heat-clearing and blood-stasis activators drugs. The medicinal properties of high frequency oral Chinese materia medica were mainly slightly cold, flat and cold,and the tastes were mainly bitter and sweet, and the meridian were mainly liver, heart, spleen and lung. The medicinal properties of high-frequency external Chinese materia medica were mainly cold and warm, and the tastes were mainly bitter and pungent, and the meridian were mainly liver, heart, spleen and stomach. There were 22 rules of association for internal TCM and 7 for external use. The clustering analysis divided oral drugs into 5 categories and topical drugs into 4 categories.Conclusion:TCM treatment of SVT is based on clearing heat, activating blood circulation and resolving blood stasis, and matching with the syndromes, which reflects the holistic concept of TCM and the perspective of syndrome differentiation and treatment.
ABSTRACT
Background: The aim of this study was to assess clinico-epidemiological profile, prevalent treatment practices and outcome of snake bite patients in a tertiary care hospital in a hilly North central region of Himachal Pradesh. Methods: A hospital record based retrospective descriptive study was done which included demographic data, clinical profile, prevalent traditional treatment methods of snake bite, treatment given at hospital and outcome among 144 patients. Results: The 123 (83%) patients were young (age group of 17-50 years) and number of female patients was 89 (62%), 29 (38%) more than male patients. Most of snake bite cases recorded, presented in the months of July to September 56 (72.7%). The most frequently bitten sites were the upper limbs particularly left hand. 61 (42%) of patients presented without any features of envenomation. Hematotoxicity was the commonest presentation in 68 (82%) of patients followed by neuroparalysis in 26 (18%) of the symptomatic cases. Green snake (Green pit viper) was the commonest snake seen. Cure rate in our study was more than 80%. Major reason for delayed presentation was consultation of traditional healers. Conclusions: In the tropics and subtropics, snake bite is a life threatening health hazard especially in poor rural people who usually waste precious time by indulging in harmful activities. This needs public as well as health care workers’ awareness and prompt intervention in a health care facility.