Assess the Depression and Quality of Life among Women Suffering from Selected Gynaecological Cancers Attending Oncology Units of Selected Hospitals

Backgrounds: Gynecological cancers are significant and probable life-threatening diseases that harm patients' physical and psychological health. The leading cause of death in female抯 psychological problems like depression endure and can cause an extra burden during their treatment. Therefore, this study helps evaluate depression and well-being among gynaecological malignancies. Methods: Women's depression was evaluated by a standardized CES-D Scale and QOL by WHOQOL Bref scale, a sample of 100 women with cancers admitted at HSK and Kerudi cancer hospital, Bagalkot was selected using a purposive sampling technique, descriptive survey design was adopted. Statistical data were tested and scrutinized using descriptive and inferential analysis. Results: 100% of women had moderate depression. The mean percentage of depression score was 61.45% with mean and SD (37�9). Of the women, 71 % had moderate, 21%had poor, and 8% had good QOL. The mean percentage of QOL of women was 48.1% with mean and SD (62.5�.1). A Strong relation was found between depression scores with your family members known to you (?=4.52, p<0.05), Area of residence (?=3.88, p<0.05), and whether you have undergone previously any surgery for the treatment of cancer (?=8.93, p<0.05). No association was found between QOL scores with study variables. A Negative correlation (r=-0.27, p<.05) was found between depression and Total QOL scores. Conclusion: Most patients have moderate depression and moderate QOL. This study is effective in identifying depression and QOL

Un caso de publicación en revista médica pirata / A case of publication in a predatory medical journal

Las revistas piratas o depredadoras (predatory journals en inglés) son cada vez más frecuentes y sorprenden en su buena fe a investigadores/as que buscan publicar sus manuscritos. Este artículo presenta un caso de descubrimiento y demostración de publicación en una revista pirata y un conjunto de sugerencias para evitar este error, como un aporte a profesionales de ciencias de la salud que realizan actividades de investigación. El resultado de las investigaciones mostró que la revista European Journal of Gynaecological Oncology(EJGO) es una revista pirata: fundada en 1980, solo desde 2020 posee International Standard Serial Number (ISSN) digital: sus primeras editoras, hasta 2020, no trabajaban en el área disciplinar de la revista ni pudieron ser rastreadas en ORCID; su actual editor no responde correos; la dirección postal de la editorial es la misma de una empresa canadiense importadora de juguetes. Hasta 2021 no poseía una plataforma web para el envío del manuscrito sino se enviaba el trabajo a un correo electrónico genérico. A raíz de nuestras denuncias fue suspendida de Scopus (Scimago) y Clarivate (Web of Science). Cuando Clarivate forzó a EJGO a avisar a sus lectores que estaba suspendida, inmediatamente cambió su página web y la empresa editora. En síntesis, se muestra un caso real de publicación en una revista pirata, la detección y comprobación de que dicha revista efectivamente cae en esta categoría y el aporte de conceptos y definiciones para tener en cuenta a fin de evitar caer en este error. (AU)

Predatory journals are becoming more frequent every day and surprise researchers who seek to publish their manuscripts. This article presents a case of discovery and demonstration of publication in a predatory journal and a set of suggestions to avoid this error, in a contribution to the education of health science professionals. The result of the research showed that the European Journal of Gynaecological Oncology (EJGO) is a pirate journal: founded in 1980, it obtainthe digital International Standard Serial Number (ISSN) in 2020; its former editors, until 2020, do not work in the disciplinary area of the journal and could not be tracked in ORCID, the new editor did not respond any mail; the postal address of the publisher is the same as that of a Canadian toy import company. Until 2021, it did not have a web platform for sending the manuscript, but rather the work was sent to a generic email. As a result of our complaints, it was suspended from Scopus (Scimago) and Clarivate (Web of Science).When Clarivate forced EJGO to notify its readers that it was suspended, it immediately changed its website and publisher. In brief, a real case of publication in a predatory journal is shown, the detection and verification that this journal actually falls into this category and contribution of concepts and definitions to avoid falling into this error. (AU)

The effect of CAM comprehensive nursing interventions on the improvement of quality of life to patients with breast cancer and gynaecological tumours

Breastcancerin females, which is consideredthe most dreadfuldisease in India andthe worldas compared toother gynaecological cancers,demands extensive care and proper medicationin order to control itsprogressive growth. In addition to the conventional care ofthe patients, Complementary andAlternative Medicine(CAM)is administeredin a controlled way through proper guidance and counselling in orderto attainimprovedphysical andmental health forthe patients.Objective: The aim of the study wasto assess the effectiveness of CAMcomprehensive nursing interventionsand their benefit forpatients who havebreast cancer and gynaecological tumours.Methods: Statistical data was used to map the adult womendiagnosed with breast and gynaecological cancer and who were set to start new chemotherapy treatments. A total of 450 patients from different states of East India were enrolled in the studyover a period of four years. The patients wereselectedbased on their preference for undergoing CAM.The research was conducted usingacross-sectionalanonymous self-administered questionnaireto examine women's perspectivestowards the use of CAM and itseffect on their mental andphysical health.Results:42%of the women preferred theuseofCAM astheir alternative treatment. Breast cancer patients disclosed that 48.1% of them had used CAM and 39% of women with gynaecological cancersstated that they had usedCAM. The results further indicated a less frequent deteriorationin the health of CAM users(38.4%) thantonon-users(55%). In terms of those who utilizedvitamins and nutritional diets,60% of the participants reported using a proper diet, including antioxidants, minerals, vitamins and herbs etc. 37% opted for spiritual healing through yoga, 26% utilized energy healing, 42.4% utilized acupuncture,72% preferred massagesand 23% of patients utilized chiropractic methods.The use of CAM was foundmainlyin the patients with proper education and awareness and those with a family history of cancer who were not receiving the necessary care from their previous primary physician.Conclusion:CAM still requiresextensive research in terms of its applications in dealing with patients and in orderto successfully launch programmes aimed at promoting its useworldwide andto eradicate all the other false notions about it.[Ethiop. J. Health Dev. 2022; 36(2):000-000]Keywords: Breast Cancerand gynaecological tumours,Complementary And Alternative Medicine (CAM), Complementary Oncology,Quality Of Life, Nutritional Diet and Spiritual Healing, HRQL (Health-Related Quality Of Life).IntroductionCancer has been the primaryconcern in Indiafrom the onset,resulting in thousands of deaths due to the lack of adequatemedication and therapy.Breast cancer is considered to bea common invasive form of cancer which is responsible for the second highest mortality rate among the primaryfatal conditions of cancer-causing deaths in women. Under the National Cancer Registry Program,the breast, cervix, uteri,and oral cavity(7)are the most common cancer sitesin women. According to statistics, 50-60% of all cancers amongIndian women are commonly found inthe cervix uteri, breast, corpus uteri and ovaries,which are the main organs forcancer invasion. The percentage of women who experience these types of cancer is increases, with more women becoming susceptible to breast cancer, in women up to 3-8% suffer fromovarian cancer,0.5-4.8%have cancer of the corpus uteri, 1-3% have vulva and/or gestational trophoblastic tumours and a staggering75,000 or more women have breast cancer. With the advancements of the disease through time,research programs were also improved in order to enable the improvement of existing measures and/or the development of new measures aimed at combating the diseas and decreasing mortality rates. Apart from the conventional chemotherapy technique,various other programs have been introduced andencorporated into treatment regimes in order to improve the lives of those who are affected by cancer.Complementary andAlternative Medicine (CAM) emphasizesthe methods and practices that are therapeutic and which help diagnose or curethe disease,these methods are intended tocomplement the conventional methods and can be used in place of mainstream medicine. Women with breast cancer and other gynaecological tumoursare increasingly inclined towards the use of CAM. With the increasing number of cancer reports in Indiaand the world,and with the principal amount leading to mortality, women with proper education and awareness are inclined to choosealternative methods rather than the old conventional ones. The side-effects resulting from the chemotherapy are immense and toxic,which is one of the reasons women are inclined to choose.Various research projects and cumulative studies have been conducted in order to review and discoverthe

Laparoscopic cystectomy in treating women with endometrioma and pregnancy outcome – a case series

@#Introduction: The aim of this study was to determine the spontaneous pregnancy rate and safety of our surgical technique of performing laparoscopy cystectomy for endometrioma

Surgical management of the patient with factor V deficiency: a case report

Factor V(FV) is a rare bleeding disorder that its incidence is one in a million. Patients with FV deficiency have typically mucosal bleeding and prolonged bleeding after an invasive procedure. There are no certain treatment modalities and there is no product of FV concentrates in the markets. The bleeding diathesis and protect the ovarian viability are a challenge as an opposite situation for treatment options and ovarian preservation after detorsion is controversial. We aimed to provide ovarian blood-stream,control bleeding and protect thromboembolism from the patient with all of our treatment in the light of literature and a few case reports.

Gynaecological malignancies in Azare, North-East Nigeria: an assessment of types, stage at presentation and treatment affordability

Background: In many parts of the world, presentations for most gynecological cancers are late; this makes treatment difficult due to the cost of chemotherapy or radiotherapy which form the bedrock for cure or palliation. Objective of this study was to determine the types, stage at diagnosis, affordability of care and outcome of treatment of gynaecological cancers in Federal Medical Centre Azare, Bauchi State, Nigeria.Methods: All cases of gynaecological cancers seen over a ten-year period, from 1st January, 2003 to 31st December, 2012 were reviewed retrospectively. The number of all gynaecological cases seen during the period was also extracted.Results: Gynaecological cancer cases accounted for 11.84 % of 8,642 gynaecological cases seen during the period of study.  The mean age and parity of the women were 42±5 SD years and 5±1 SD respectively. Cervical cancer accounted for 55 %, ovarian cancer 30%, endometrial cancer 6%, choriocarcinoma 5%, secondaries/ cancers of undetermined origin were 4%.  Ninety-two percent presented with advanced stage of diseases. Only 25.3% could afford the cost of full treatment, and 8.4% attained cure of their disease. The modalities of treatment available were surgery and chemotherapy.Conclusions: Cervical and Ovarian Cancers remain the leading types of gynaecological cancers in our environment and late presentations are frequent occurrence. Late presentation and unaffordability of treatments are major challenges associated with the management of these patients. Early presentation and funding mechanisms for gynaecological cancers are keys to improved cure rate and reduced mortality.

Effect of Intra-Operative Intravenous Crystalloid Infusion on Post-Operative Nausea and Vomiting after Diagnostic Gynaecological Laparoscopy- Comparison of 30 mL/Kg & 15 mL/Kg.

Laparoscopic procedures have the advantages of minimal incision, early recovery, lesser post-operative pain and early ambulation. However, they are associated with an increased incidence of post-operative nausea and vomiting (PONV), which is all the more frequent in gynaecological laparoscopic surgeries. In our study, we have evaluated the effectiveness of intra-operative intravenous crystalloid infusion on post-operative nausea and vomiting after diagnostic gynaecological laparoscopy.METHODSInformed consent was obtained and patients were randomly divided into two groups. Group 1 received 30 mL/Kg intravenous crystalloid infusion intra operatively and group 2 received 15 mL/Kg intravenous crystalloid infusion. Incidence of nausea, incidence of emesis (retching or vomiting), the amount of rescue antiemetic used, and the haemodynamic parameters were noted in the postoperative period for 12 hours for both the groups.RESULTSIncidence of PONV was much more in group 2 in 0, 1, 2, 3, 4, 6 hours post operatively and rescue antiemetic use was much more in group 2 in total 12 hours post-operative period. There was no statistically significant difference in hemodynamic parameters between Group 1 and Group 2.CONCLUSIONSIntra-operative administration of 30 mL/Kg of crystalloid infusion significantly reduces the incidence of PONV and rescue antiemetic use compared to 15 mL/Kg crystalloid infusion in diagnostic gynaecological laparoscopy. So, it can be used as a non-pharmacological method for prophylaxis of PONV.

Review of Gynaecological Diagnoses and Surgeries Performed at a Tertiary Health Facility in Niger-Delta of Nigeria from 2012-2017: Implications for Healthcare Planning and Budgeting

Background: Gynaecological disorders are a particularly common cause of morbidity and mortality among women of reproductive age and a common cause of hospital presentation/admission and surgery.Objective:This study sought to review gynaecological diagnoses and surgeries performed in a tertiary health facility from 2012 to 2017 and its implication for healthcare planning and budgeting.Methodology:This was a retrospective review of all gynaecological diagnoses and surgeries seen in the Rivers State University Teaching Hospital (RSUTH) from 2012 to 2017.Data were retrieved using a proforma comprising of year, gynaecological diagnosis and gynaecological surgeries. Data obtained was entered into Microsoft Excel for descriptive analysis.Results:The proportion of clinic attendees declined from an average of 23% in the first three years (2012-2014) to about 10% in the last three years (2015-2017). The most common gynaecological diagnosis were uterine fibroid (33.3%), infertility 28.1% (primary 5.7%, secondary 22.4%), PID (5.9%), ovarian tumour (4.2%), secondary amenorrhea (3.4%) and pelvic malignancies (3.4%). The commonest major surgeries were myomectomy 441(33.7%), salpingectomy 345(26.4%), hysterectomy 168(12.8%) and cervical cerclage 122(9.3%). The commonest minor surgeries were manual vacuum aspiration 314(41.0%), examination under anaesthesia and biopsy 110(14.3%) and adhesiolysis for synechiae 97(12.6%). The duo of uterine fibroid and infertility made up 50%-70% of all gynaecological diagnoses.Conclusion:This study showed that there has been a steady decline in gynaecological consultations over the years. However, the duo of uterine fibroid and infertility made up half to three-quarter of all gynaecological diagnoses over the 6 years. Infertility and uterine fibroids have a long cause and effect association. Healthcare policies and budgeting should be increased towards tackling these conditions, especially the setting up of a fertility center to provide assisted reproductive technologies and laparoscopy to improve practice and patient outcome

Association between quality of life and handgrip strength among malnourished gynaecological cancer outpatients, National Cancer Institute

@#Introduction: Malnutrition is common among cancer patients and it is reported in a significant proportion of patients with gynaecological cancer (GC). The aim of this study was to determine the association between quality of life (QOL) and hand grip strength (HGS) among malnourished GC outpatients in the National Cancer Institute (NCI). Methods: This study was carried out in a Multidisciplinary Clinic of NCI. HGS was measured using Jamar Hand Dynamometer. Nutritional status was assessed using the scored Patient-Generated Subjective Global Assessment (PGSGA). QOL was measured using the validated European Organisation for Research and Treatment of Cancer Questionnaire (EORTC-QLQ C30). Results: A total of 69 patients were selected for the study. Fifty eight (84.1%) were classified as moderately malnourished or at risk of malnutrition (PG-SGA B) and 11 (15.9%) were classified as severely malnourished (PG-SGA C). There was a moderate, significant positive relationship between HGS and functional status (rs=0.275, p=0.022) observed in this study. Besides, in malnourished GC patients with low HGS, results indicated that they had problems with social functioning as well (r=0.255, p=0.035). Appetite was suggested as a predicting factor for low HGS among malnourished GC patients (F=12.253, p=0.001). Conclusion: HGS is a simple objective indicator of functionality and is, therefore, a valid item to be measured when assessing QOL of malnourished GC outpatients.

A Study of drug utilization pattern in gynaecology out-patient department of a tertiary care hospital

Background: Gynaecological diseases are common in India because of socioeconomic, hygienic and literacy problems. Gynaecological drugs are one of the strong selling drugs in pharmaceutical market. Drug utilization research facilitate appropriate use of drugs in patient, minimize the adverse event and lead to better patient outcome. So, the present study was carried out to examine the patterns of drug prescription.Methods: A retrospective, observational study was done by collecting the prescriptions of the patients who attended the Gynaecology out-patient department in our institute for the period of six months. Total 300 prescription were collected and analysed. Patient’s demographic data, total number and category of drugs prescribed, percentage of individual drug and their dosage forms, drugs prescribed by generic name, brand names and percentage of drugs prescribed from essential drug list were analysed.Results: The mean age of presentation was 36.6±10.98 years. Among infective group breast abscess were common and among non-infective cases dysmenorrhea was most common. Out of 754 drugs prescribed, minerals were most commonly prescribed (42.70%) followed by antimicrobials (24.53%). Tablet form were prescribed more commonly (96.02%) followed by capsules (2%) and injections (1.06%). The average no. of drugs per prescription was 2.51±1.26 SD. Percentage of drugs prescribed by generic name were 98.01% and drugs prescribed from essential drug list were 85.41%.Conclusions: The overall drug use pattern in our study correlates with various gynaecological diseases. Majority of the women from rural background depend on primary health services for gynaecological diseases in their areas so, strengthening of gynaecological health care services reduce the morbidity among the women from rural areas.

Chronic uterine inversion associated with uterine leiomyoma misdiagnosed as cervical fibroid: a case report

Chronic inversion of uterus is a rare clinical entity which is usually associated with obstetrics complication and rarely with gynaecological disorder like fibroid present at fundus of uterus. We here present a case of 40-year-old female P3L3 with chronic inversion of uterus with fundal fibroid which present with 3year history of abnormal vaginal bleeding. Ultrasonography and MRI revealed cervical fibroid. Due to AUB secondary to cervical fibroid decision of hysterectomy was taken. On laparotomy chronic uterine inversion was present which was corrected by haultain’s procedure. Then hysterectomy was done. Histopathology report suggestive of uterine leiomyoma at fundus of uterus. Chronic uterine inversion associated most commonly with fundal submucous leiomyoma. Other causes are leiomyosarcoma, endometrial carcinoma, cervical carcinoma, rhabdomyosarcoma, mixed mullerian sarcoma. It is an extremely rare gynaecological condition and can be misdiagnosed as cervical fibroid, advanced cervical malignancy or other causes of AUB in females. It could be labelled as gynaecological near miss so a high index of suspicion is necessary for it’s diagnosis.

Total laparoscopic hysterectomy: an experience at a tertiary care hospital

Background: This study is aimed to review indications, demographic data of patients, clinical outcomes and safety of total laparoscopic hysterectomy.Methods: This is a prospective observational study of total 150 patients who underwent total laparoscopic hysterectomy (TLH) from 1st June 2017 to 30th November 2018 in GMERS Civil Hospital Sola.Results: ~45% patients were between 40-50 years age group; 60% patients had 2 or more deliveries; commonest indication was symptomatic adenomyosis ; uterine size in ~57% of patients were up to 6 weeks; duration of surgery in ~91% of patients <120 minutes; intraoperative blood loss in all cases <200ml; no intra-operative and postoperative complications were encountered.Conclusions: TLH is safe procedure with minimal blood loss, minimal postoperative pain and discomfort and shorter duration of hospital stay when performed via expert hands.

Clinico-epidemiological Profile Of Patients With Gynaecological Malignancies Being Followed-up At A Radiation Oncology Department Of A Tertiary Care Government Institute Of India

Background: Gynaecological malignancies constitute a major burden of cancer-related morbidity and mortality amongst females in developing countries including India. Aims and objectives: The study was conducted to study the clinical and morphological characteristics of patients having gynaecological malignancies and treated by radiotherapy with or without chemotherapy, now under follow-up. Study design: Aretrospective observational study in a tertiary care hospital of government set-up over 2 year period. Observations: A total of 3120 patients who reported for follow-up were included, of which 394 patients were of gynaecological malignancies. Carcinoma (Ca) Cervix followed by Ca endometrium were the most common sites (76% and 16% respectively). The most common age group was 7th decade. 33% patients with locally advanced cervical cancer were found to have paraaortic lymphadenopathy on presentation warranting extended field radiotherapy (RT). 73% of locally advanced ca cervix patients received 5 or more cycles of weekly chemotherapy (CT) with Cisplatin. 68% patients were disease-free at the time of follow-up. 11% patients were referred for palliative chemotherapy. 17% patients required hospitalization for symptomatic care during followup. Conclusion: Concurrent chemoradiation is an acceptable and well-tolerated modality of treatment for locally advanced gynaecological malignancies. Multimodal treatment and good collaboration between allied specialists is recommended.

Adolescent gynae clinic - need of the day: a prospective study at a tertiary care centre

Background: To study common gynaecological problems in adolescent girls and to establish the need of adolescent clinic.Methods: A prospective study was conducted including 250 adolescent girls attending gynaecology OPD. Girls were evaluated by detailed history, thorough clinical examination and investigations such as haemogram, coagulation profile, hormonal assays, ultrasound examination of abdomen and pelvis, as and when indicated.Results: Majority of girls had complaints related to menstrual disorders i.e. 58.3%. Most common causes of menstrual abnormalities were dysfunctional uterine bleeding (42.85%) followed by polycystic ovarian syndrome (26.19%) and pelvic inflammatory disease (15.47%).Conclusions: Problems are specific to this age group, setting up of separate adolescent clinics is desirable of efficient management where they can be provided adequate privacy to discuss their problems openly.

Preventable gynecological surgeries in hysterectomized women : a review of causes and measures of prevention

Background: Hysterectomy, the most common gynaecologic surgery performed around the world. however, repeat gynaecologic intervention / surgery may be required for some conditions, adding cost and morbidity for patients and posing a burden on healthcare systems. The objective of the present study was to find out the incidence of  and types of surgical intervention required post hysterectomy.Methods: A retrospective analysis of hospital records was done for gynecologic operative procedures done in post hysterectomy patients 2014-2016.Results: Out of a total of 1028 in the year 2014-2016 in our centre, 75 (7.3%) surgeries were performed for benign conditions in hysterectomized women.  Hydrosalpinx(29%) was most common condition for surgery, followed by endometriosis(24%) with   31-40 years age group women   undergoing  the maximum surgeries. Vault prolapse(16%) in elderly and vaginal vault  granulation(16%)  in younger women  also underwent a repeat gynecological procedure post hysterectomy.Conclusions: Some measures can be taken during the primary surgery(hysterectomy) to prevent a repeat gynaecological surgery in these women. Concurrent salpingectomy can prevent  benign and malignant fallopian tube lesions and ovarian cancer . Endometriosis surgery should be precise to prevent any remnant ovarian or endometriotic foci. McCall’s culdoplasty  in primary hysterectomy is proven to prevent vaginal vault prolapse. Most  genitourinary  fistulas can be prevented by detailed  knowledge  of pelvic anatomy, preoperative risk stratification of patients at higher risk of ureteric and urinary bladder injuries,  meticulous surgical technique and judicious use of electrosurgical energy. Prevention is always  better than a repeat surgery.

Accuracy of 2D ultrasound and Doppler ultrasound findings for the diagnosis of placenta accreta in pregnant women with risk factors / Exactitud de los hallazgos ecográficos 2D más ecografía doppler para el diagnóstico de acretismo placentario clínico en gestantes con factores de riesgo

ABSTRACT Objective: To determine the accuracy of 2D ultrasound and Doppler ultrasound for the diagnosis of placenta accreta in pregnant women with risk factors when compared to clinical diagnosis. Materials and methods: Study of diagnostic accuracy for the assessment of placenta accreta in high-risk patients who ended their pregnancy between 2014 and 2016 at Hospital Universitario de Santander. After obtaining their informed consent, 51 pregnant women over 18 years of age, more than 12 weeks of gestational age, low or anterior placenta or a history of uterine surgery were included. The diagnosis of a high probability of placenta accreta based on the presence of at least two ultrasound criteria and one Doppler criterion was compared with the gold standard of the visual finding during the cesarean section and of the surgical specimen in patients taken to hysterectomy, or during the clinical course in women with vaginal delivery. Sociodemographic and clinical variables are described, and the sensitivity and specificity, and positive or negative odds ratios are estimated. Results: The diagnosis of high probability of placenta accreta based on 2D Doppler Ultrasound has a high sensitivity of 88.2% (95% CI: 70.0-100) and specificity of 97.1% (95% CI: 89,9-100), with positive LR of 30.0 (95% CI: 4.3-208.5) and negative LR of 0.12 (95% CI: 0.03-0.45). Conclusions: The diagnosis of high probability of placenta accreta using non-invasive imaging provides valuable information regarding the presence and extent of placenta accreta in patients with known risk factors.

RESUMEN Objetivo: Establecer, en gestantes con factores de riesgo, la exactitud de la ecografía 2D más Doppler para hacer el diagnóstico de acretismo placentario al compararlo con el diagnóstico clínico. Materiales y métodos: Estudio de evaluación de la exactitud diagnóstica en gestantes de alto riesgo de placenta ácreta que terminaron el embarazo entre 2014 y 2016 en el Hospital Universitario de Santander. Previo consentimiento informado se incluyeron 51 gestantes mayores de 18 años, con más de 12 semanas de edad gestacional, con placenta baja o anterior, o antecedentes de cirugía uterina. Se comparó el diagnóstico de alta probabilidad de acretismo placentario dado por la presencia de, al menos, dos criterios en la ecografía 2D y uno en el Doppler, con un patrón de oro dado por el hallazgo visual durante la cesárea y la pieza quirúrgica en las que fueron llevadas a histerectomía, o la evolución clínica en las mujeres con parto vaginal. Se describen las variables sociodemográficas y clínicas, y se calcula la sensibilidad, especificidad y razón de probabilidades positiva y negativa. Resultados: El diagnóstico de alta probabilidad de acretismo placentario dado por ecografía 2D más Doppler tiene una sensibilidad del 88,2 % (IC 95 %: 70,0-100) y especificidad del 97,1 % (IC 95 %: 89,9- 100), LR positivo de 30,0 (IC 95 %: 4,3-208,5) y LR negativo de 0,12 (IC 95 %: 0,03-0,45). Conclusiones: El diagnóstico de alta probabilidad de acretismo placentario por imágenes diagnósticas no invasivas ofrece información valiosa sobre la presencia y extensión del acretismo placentario en pacientes con factores de riesgo conocidos Palabras clave: acretismo placentario, ultrasonografía doppler, técnicas de diagnóstico obstétrico y ginecológico.

Diagnostic Indicators for Blood Stasis Syndrome Patients with Gynaecological Diseases / 中国结合医学杂志

<p><b>OBJECTIVE</b>To investigate the important diagnostic indicators for blood stasis syndrome (BSS) in patients of childbearing age with gynaecological diseases.</p><p><b>METHODS</b>A partial least squared-discriminant analysis (PLS-DA) were applied to BSS symptoms data of patients with gynaecological diseases, and the diagnostic indicators used by doctors of Korean medicine (DKMs) among BSS patients with gynaecological diseases were also investigated.</p><p><b>RESULTS</b>A total of 103 patients of childbearing age with gynaecological diseases and 40 healthy controls were enrolled. Among the 103 patients, 63 (61.7%) and 40 (38.8%) were diagnosed with BSS and non-BSS, respectively, and BSS patients exhibited a more severe extent of disease. A score plot of PLS-DA showed clearly different patterns among the 3 groups. Based on the variable importance on projection of PLS-DA model, menstrual pains, dark lumps in the menstrual blood, ileocoecal tenderness and resistance, sharp pains, and sublingual varicosities were selected as the top five most important indicators. Moreover, more than 75% of DKMs chose dark lumps in menstrual blood, menstrual pain, and dark menstrual blood as the diagnostic indicators of BSS in patients with gynaecological diseases, and more than 49% of them also considered sharp pains, dark red tongue, sublingual varicosities, and tendency to bruise easily as diagnostic indicators of BSS.</p><p><b>CONCLUSION</b>DKMs focused on menstrual symptoms and certain gynaecological symptoms to diagnose BSS patients of childbearing age with female diseases.</p>

Non-bacterial thrombotic endocarditis: A rare manifestation of cervical adenocarcinoma

@#Non-bacterial thrombotic endocarditis (NBTE) denotes the presence of sterile non-infective vegetation on structurally normal, or subtly degenerate cardiac valves and is often associated with advanced malignancies. In gynaecological cancer in particular, NBTE has been most commonly associated with ovarian cancer.1,2 Here we report a rare but interesting case of NBTE in a patient with locally advanced cervical adenocarcinoma.

Research progresses of stereotactic body radiotherapy in gynaecological cancers / 中华放射医学与防护杂志

Stereotactic body radiation therapy(SBRT) is a new technology developed in recent years.The advantage of the technique resides in its ability to provide a high dose to tumor but spare normal tissues to an extent.The use of SBRT in gynecological cancers mainly concentrated in local treatment of pelvic recurrence,para-aortic lymph node metastasis and oligometastatic disease.SBRT boosts to macroscopic recurrences and oligometastatic disease can provide local control and a possibility of long-term disease-free survival in carefully selected patients.However,patients who received SBRT following prior irradiation,despite its tight conformality,were still confronted with significant morbidity.SBRT can be used as an alternative treatment for locally advanced cervical cancer after external-beam radiation therapy in patients who are unsuitable for brachytherapy.

Asssessment of some selected vitamin levels in patients with vesico - vaginal fistula in Jos, Northern Nigeria / Evaluación de niveles de vitamina seleccionados en pacientes con fístula vesico - vaginal en Jos, norte de Nigeria

Globally, about 3.5 million women are living with genitourinary fistula, a miserable condition. Obstetric Vesicovaginal fistula (VVF) is exceptionally rare in developed part of the world, where it is mostly due to gynaecological cause. The study was conducted to provide baseline data on vitamin A and vitamin E levels among Vesico - Vaginal Fistula (VVF) patients and to establish their socio-demographic characteristics. Some selected vitamin levels in patients with Vesico - Vaginal Fistula (VVF) in Jos, Northern Nigeria were investigated using spectrophotometric method. Samples were collected from VVF patients undergoing treatments at the Evangel Hospital, Jos and the controls were non pregnant but parous women of similar social status who were willing to participate in the study. A total of 97 participants made up of 67 VVF patients and 30 controls were involved in the study. The results revealed that only 1 clients (1.49%) was mulliparous, 50 (74.64%) and 16 (23.88%) clients were multiparous and grand multiparous respectively out of 67 (100%) clients. The results of social class distribution in both clients and control is in the order of 5>4>3, 2>1. The levels of vitamin A in VVF clients showed no significant change (p>0.05) when compared to control while that of vitamin E showed significant change (p<0.05). The results of viatamin A and E in respect to age, social class and parity showed significant difference (p<0.05) in the VVF patients than the control except for those with age 25 - 29 and 40 - 44 years as well as social class 1 and 5. The study therefore highlights need for determination of reference values of vitamins levels among African population

A nivel mundial, alrededor de 3,5 millones de mujeres viven con fístula genitourinaria. La fístula vesicovaginal (FVV) obstétrica es excepcionalmente rara en el mundo desarrollado, donde se debe principalmente a causas ginecológica. Este estudio se realizó para proporcionar datos de referencia sobre los niveles de vitamina A y vitamina E entre los pacientes con FVV y para establecer sus características sociodemográficas. Los niveles de vitamina A y E en pacientes con VVF en Jos, norte de Nigeria se investigaron mediante el método espectrofotométrico. Se recogieron muestras de pacientes con FVV que se sometieron a tratamientos en el Evangel Hospital, Jos y un grupo control de paciente, no embarazadas del mismo estatus socioeconómico que estaban dispuestas a participar en el estudio. Un total de 97 participantes formados por 67 pacientes con FVV y 30 controles participaron en el estudio. Los resultados revelaron que solo 1 paciente (1.49%) era nulípara, 50 (74.64%) y 16 (23.88%) de las pacientes eran multíparas y multíparas grandes, respectivamente. Los resultados de la distribución socioeconómica en el grupo de embarazadas y el control fue en orden de 5> 4> 3, 2> 1. Los niveles de vitamina A en paciente con FVV no mostraron diferencias significativas (p>0.05) en comparación con el control, mientras que los niveles de vitamina E sí mostraron diferencias significativas (p<0.05). Los resultados de la vitamina A y E con respecto a la edad, clase socioeconómica y paridad mostraron una diferencia significativa (p<0.05) en los pacientes con FVV respecto control, excepto para los de 25-29 y 40-44 años, así como para la clase social 1 y 5. Por lo tanto, el estudio destaca la necesidad de determinar los valores de referencia de los niveles de vitaminas en la población africana.