ABSTRACT
Objective To understand the prevalence of depression and anxiety symptoms in human immunodeficiency virus/anxiety symptoms in acquired immunodeficiency syndrome (HIV/AIDS) patients,and the possible factors of depression and anxiety symptoms,to provide the basis for promoting the physical and mental health of HIV/AIDS patients.Methods Cross-sectional survey of 1384 cases of HIV/AIDS outpatient and inpatient in Changsha Hospital affiliated to University of South China were carried out by using the the self-rating depression scale (SDS) and the self-rating anxiety scale (SAS),and the influencing factors of depression and anxiety symptoms were analyzed with logistic regression.Results In 1384 HIV/AIDS patients,the detection rate of depression and anxiety symptoms was 36.6％,and 198 patients was diagnosed the depression and anxiety (14.3％).Multi-factor regression analysis showed sex (OR =2.632,95％ CI:1.814-3.817),cognitive function (OR =3.006,95％ CI:2.043-4.424),combined diseases (OR =4.009,95％ CI:3.036-5.295),adverse drug reactions (OR =2.580,95 ％ CI:1.736-3.834),opportunistic infections (OR =6.994,95％ CI:4.863-10.060) are the risk factors of depression and anxiety symptoms in HIV/AIDS patients.Platelet count (OR =0.610,95％ CI:0.390-0.954) is the protective factor of depression and anxiety symptoms in HIV/AIDS patients.Conclusions Depression and anxiety are common in HIV/AIDS patients.Women,HIV associated neurocognitive dysfunction (HAND),combined with other diseases,opportunistic infections,and adverse drug reactions to HIV/AIDS patients are more likely to have depression and anxiety,and should be paid attention to in the follow-up process.
ABSTRACT
Objective To investigate the prevalence of tuberculosis (TB) in human immunodeficiency virus (HIV) positive population and explore its influencing factors.Methods Cluster sampling was used,continuous 205 cases who were diagnosed as HIV positive from December 16,2002 to June 30,2012 in Zhuhui district and Yanfeng district of Hunan province and could be followed up and traced were enrolled in the study.All patients were screened after informed content through questionnaire,sputum smear examination,chest X-ray examination,liquid culture (BACTECTM MGITTM 960 operating system),mycobacterium species identification (for liquid culture positive) and CD4 testing.Univariate and multivariate analyses were conducted to identify the impacts of different sex,age,and TB suspect syndromes,etc.Results Of 205 cases,19 were diagnosed as tuberculosis.The rate of TB/HIV was 9.3％.Univariate analysis showed that age,annual household net income,being acquired immunodeficiency syndrome (AIDS) patients and with TB suspect syndromes had significant impacts on tuberculosis combining (P ＜ 0.05).While multivariate analysis showed that age (OR =1.443) and TB suspect syndromes (OR =3.124) were risk factors influencing TB combining in people living with HIV (PLHIVs).Conclusions TB prevalence in HIV positive population was higher in Zhuhui district and Yanfeng,those aged and with TB suspect syndromes cases had higher risk to develop tuberculosis.TB screening should be reinforced in HIV positive population.