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Background: The alarming spread of the COVID-19 pandemic has led to a shortage of RT-PCR kits in Uganda necessitating the use of high-resolution chest Computed Tomography to guide patient management and treatment. Main Objective: To describe the chest HRCT findings in patients with clinically suspected COVID-19 pneumonia and to compare its diagnostic accuracy to RT-PCR. . Methods: In this cross-sectional study, chest HRCT findings of 384 patients and available RT-PCR laboratory results were reviewed and recorded in the data collection form. Results: The commonest chest HRCT findings were bilateral ground glass opacities (78.2%). Out of the 31.7% patients that took the PCR test only 26.9% tested positive. 16 out of 17 patients who tested negative, were classified under CORADS 5. The sensitivity of chest HRCT was 90.4%, 95% CI (82.6-95.5), positive predictive value of 84.2%, 95% CI (75.6-90.7), and accuracy of 77.5%, 95% CI (71.5-87.1). Conclusions: HRCT was found superior to RT-PCR in diagnosing COVID-19. A patient with positive HRCT findings should be treated as COVID 19 when RT-PCR is inaccessible or results are negative. A patient with negative HRCT requires complimentary RT-PCR and possibly follow up CT scans if symptoms persist before treating for COVID 19.
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SARS-CoV-2 , COVID-19ABSTRACT
Background: During the Covid -19 pandemic, there was a need to diagnose the infection at an earlier stage for better treatment and containment of the disease.The standard method of detection was by the real-time reverse-transcription polymerase chain reaction (RT-PCR) tests. However in some cases when the initial PCR tests was negative, HRCT thorax played an important role for earlier detection. Aim: To test the accuracy of HRCT thorax in diagnosing COVID-19 infection in suspected patients with initial negative RT-PCR. Materials and methods: Retrospective analysis of patients with a negative RT PCR but with clinical suspicion of COVID who were referred for HRCT thorax during the initial phase of the disease, were included in the study. HRCT thorax images were categorized as per CORADS scoring system. Those patients with score of 4 or 5 were subjected to repeat RT-PCR test and results were analysed. Results: Total of 52 (33 (63%) males and 19 (37%)females) patients in age group from 36-62yrs,who had clinical suspicion of COVID and underwent HRCT were included.The CT was performed within 10 days of the illness. All these patients had a negative RT-PCR result when CT was performed.22 patients had a CORADS score of 4 and 30 patients had a score of 5. Follow up RT-PCR done within a week after the CT came out to be positive in 45(82.3%) patients. In rest of the 7 (13.4%) patients it was negative. The sensitivity of CT came out to be 84.8% which was statistically significant. Conclusion: HRCT appears to be more accurate in detection of the disease whereas RT-PCR test may produce false-negative results in the initial phase of the disease.
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Neuro?bromatosis is an autosomal dominant disorder of neuroectodermal and mesenchymal origin, also known as Von Rechlinghausen disorder. It can also occur inherited or sporadically. A mutation of NF1 gene on chromosome 17q11.2 has been recognized as a disease prompter, and the spectrum of clinical phenotype is wide because of gene complexity, size and diversity of exons. In our article we are presenting a case of neuro?bromatosis associated with diffuse cystic lung disease.
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Background: To retrospectively determine the correlation between CTseverity score & D-dimer. Methodology: This is retrospective original research of 227 patients (IPD & OPD) during April 1 to May 31, 2021 for Covid-19. Patients CTseverity scores, HRCTThorax findings, D-dimer, Platelet count and Demographic variables were recorded. The correlation between CTseverity score & D-dimer were determined. Results:Between the mentioned dates, 227 patients are taken into study which includes 146 Males & 81 Females. Mean of CTseverity score was 6.7, D-dimer was 0.46mg/l. Higher CTscore is seen in males (mean -7.1) as compare to females (mean -6.12). D-dimer are seen higher in males (mean =0.52mg/l) as compare to females (median=0.37mg/l). The study of 227 patients has shown positive correlation between CTscore & D-dimer (r=0.38, p<0.05). Males showed relatively stronger positive correlation (r=0.4, p<0 .05) than females (r=0.3, p<0.05). Patients with age less than equal to 45 has shown relatively stronger positive correlation between CTscore & D-dimer (r=0.4, p<0.05) than patients with age more than 45 (r=0.35, p<0.05). Conclusion:Pulmonary lesion induced by SARS-CoV-2 infection was associated with raised inflammatory response, impairment in exchange of gases, and end organ damage. In study, we can conclude that lung lesion may exert important role in COVID-19 pathogenesis & clinical presentation
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INTRODUCTION : In December 2019, a large outbreak of a novel coronavirus infection occurred in wuhan hubei province, china. The disease caused by the virus, named novel coronavirus disease (COVID-19) by the world health organization (WHO) can be spread through human to human contact. In human coronavirus can cause spectrum of diseases ranging from asymptomatic patient, simple cold cough to severe acute respiratory syndrome ( SARS). HRCT is very useful to see the extent of disease spread in lungs and to assess the severity of infection. It also helps in monitoring the response and therapeutic effectiveness and prognosis. AIMS AND OBJECTIVES: 1]To evaluate the various HRCT thorax Findings in RTPCR confirmed patients of covid-19 infection. 2] To correlate the findings of HRCT of thorax with patient’s clinical symptoms. METHODOLOGY: A retro- prospective clinical study was carried out on patients who were referred for HRCT thorax to the Department of Radiodiagnosis, Sheth L.G. general hospital having signs and symptoms of covid-19 and whose RT PCR report was awaited and who had undergone HRCT thorax and only patients who were RT PCR test positive within 72 hours were taken in the study. Total of 250 patients from May 2020 to January 2021, who confirmed covid-19 diagnosis with RT-PCR were taken. RESULTS In our study we found, the most common initial CT findings in COVID-19 pneumonia are bilateral, patchy or rounded ground-glass opacities that most frequently occur bilaterally and in the lung periphery with a subpleural basal predominance in left lower lobe. Most common finding were patchy bilateral ground glass opacity most commonly associated with inter and intralobular septal thickening giving crazy paving pattern. Consolidation was also seen with or without GGO suggesting infective etiology. CONCLUSION HRCT Thorax may be useful as a standard method for the rapid diagnosis of COVID-19 to optimize the management of severely ill PATIENTS.
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The study was conducted in the Department of Otorhinolaryngology, Dr Shankarrao Chavan Government Medical College, Nanded. It was a Prospective type of Descriptive study, carried out from 1st January 2020 to 21st June 2021. 60 Patients who attended the ENT OPD with signs and symptoms of Atticoantral type of chronic suppurative otitis media were included in the study. The main aims of the study were to study the Radiological findings of Temporal Bone in Atticoantral type of chronic suppurative otitits media; and to correlate the findings of HRCT temporal bone showing Atticoantral type of chronic suppurative otitits media; with intra-operative findings in Tympanomastoid surgeries
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Objective: This study aims to measure the complete and two-turn cochlear duct lengths in a Filipino population using archived CT scan images.Methods: Design: Retrospective Review of Records Setting: Tertiary Government Training Hospital Participants: CT Scan Images of 255 patientsCochlear images of patients who underwent cranial, facial, orbital, paranasal sinus and temporal bone CT scans from January 2019 to December 2019 were analyzed. Coronal oblique images from 3D multiplanar reconstructions were obtained and a single linear measurement ('A' value) was used as the spiral coefficient to calculate the complete cochlear duct length (CDL) and two-turn length (2TL).Results: A total of 510 cochlear images were obtained from the CT scan images of 255 subjects (143 males, 112 females aged 1 to 81 years; mean age = 47 years). The mean 'A' value was 8.81 mm (SD = 0.20). The mean complete cochlear duct length was 32.68 mm (31.01 mm - 35.50 mm; SD = 0.834) while the mean two-turn cochlear duct length was 29.61 mm (28.14 mm - 32.08 mm; SD = 0.732). The complete and two-turn cochlear duct lengths in males were found to be significantly longer than in females (p = .001). No significant difference was found between cochlear measurements for left and right ears.Conclusion: The mean complete cochlear duct length among Filipinos in our study measures 32.68 mm while the mean two-turn cochlear duct length measures 29.61mm. Both complete and two-turn cochlear duct lengths were longer among Filipino males than among females.
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Humans , Male , Female , CochleaABSTRACT
PURPOSE@#Auditory nerve injury is one of the most common nerve injury complications of skull base fractures. However, there is currently a lack of auxiliary examination methods for its direct diagnosis. The purpose of this study was to find a more efficient and accurate means of diagnosis for auditory nerve injury.@*METHODS@#Through retrospectively analyzing the results of brainstem auditory evoked potential (BAEP) and high-resolution CT (HRCT) in 37 patients with hearing impairment following trauma from January 1, 2018 to July 31, 2020, the role of the two inspection methods in the diagnosis of auditory nerve injury was studied. Inclusion criteria were patient had a clear history of trauma and unilateral hearing impairment after trauma; while exclusion criteria were: (1) severe patient with a Glasgow coma scale score ≤5 because these patients were classified as severe head injury and admitted to the intensive care unit, (2) patient in the subacute stage admitted 72 h after trauma, and (3) patient with prior hearing impairment before trauma. According to Goodman's classification of hearing impairment, the patients were divided into low/medium/severe injury groups. In addition, patients were divided into HRCT-positive and negative groups for further investigation with their BAEP results. The positive rates of BEAP for each group were observed, and the results were analyzed by Chi-square test (p < 0.05, regarded as statistical difference).@*RESULTS@#A total of 37 patients were included, including 21 males and 16 females. All of them were hospitalized patients with GCS score of 6-15 at the time of admission. The BAEP positive rate in the medium and severe injury group was 100%, which was significantly higher than that in the low injury group (27.27%) (p < 0.01). The rate of BEAP positivity was significantly higher in the HRCT-positive group (20/30, 66.7%) than in the HRCT-negative group (1/7, 14.3%) (p < 0.05). Twenty patients (54.05%) were both positive for BEAP and HRCT test, and considered to have auditory nerve damage. Six patients (16.22%) were both negative for BEAP and HRCT test, and 10 patients (27.03%) were BAEP-negative but HRCT-positive: all the 16 patients were considered as non-neurological injury. The rest 1 case (2.70%) was BAEP-positive but HRCT-negative, which we speculate may have auditory nerve concussion.@*CONCLUSION@#By way of BAEP combining with skull base HRCT, we may improve the accuracy of the diagnosis of auditory nerve injury. Such a diagnostic strategy may be beneficial to guiding treatment plans and evaluating prognosis.
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Female , Humans , Male , Cochlear Nerve , Evoked Potentials, Auditory, Brain Stem/physiology , Hearing Loss , Retrospective Studies , Skull Base/diagnostic imaging , Tomography, X-Ray ComputedABSTRACT
Objectives: To determine the frequency of obstructive pattern of spirometry in bronchiectasis patients. Material and methods: This case series study was conducted at Department of Pulmonology, Jinnah Hospital Lahore. Total 143 patients with bronchiectasis having age 30-60 years either male or female and having duration of symptoms ?1 years were selected for this study. Results: Total 143 patients with Bronchiectasis were selected for this study. Mean age of the patients was 47.56 ± 9.11 years, mean weight, mean height and mean BMI was 68.01 12.22, 59.63 ± 4.21 and 29.84 5.71 respectively. Out of 143 patients of Bronchiectasis, Positive obstructive pattern was noted in 80 (55.9%) patients and reversibility was noted in 45 (56.25%) patients. Conclusion:Results of this study showed a higher number of positive obstructive pattern in patients of bronchiectasis and percentage reversibility is also very high. Reversibility was significantly associated with age of the patients and duration of disease.
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Background: Aim of this study was to validate thoracic trauma severity score (TTSS) in assessing the requirement of mechanical ventilation, mortality, and predicting prognosis in chest injury patients.Methods: This study was conducted in department of general surgery, Dr. S. N. Medical College, Jodhpur, Rajasthan, from December 2018 to September 2019. This was a single centred, prospective, observational study, conducted in 110 patients, aged >18 years, of isolated chest injury, excluding polytrauma patients. Data was summarized in the form of proportions, histograms and tables to show relationships of parameters with results. Data was presented as mean±SD and proportions as appropriate. Chi square test, z test or t tests were used wherever necessary for association analysis between categorical variables. Diagnostic test characteristics for mortality and complications was calculated from the ROC curves. A two sided of p values of less than 0.05 was considered statistically significant.Results: Most common mode of chest injury was blunt trauma and most common age group affected was 42-54 years. Maximum mortality was seen in TTSS between 16-20, shows higher the TTSS more the mortality. Ventilator requirement was more in high TTSS. Patients with higher TTSS had longer hospital stay as compared to patients with lower TTSS.Conclusions: On application of TTSS on admission, TTSS had direct correlation with need for oxygenation, ventilator need, duration of hospital stay, mortality or outcome in chest trauma patients. Thus we recommend TTSS as a good useful score for evaluation of prognosis, outcome and mortality in chest trauma patients.
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Tuberculosis is one of the leading causes of mortality in a developing country like India among the infectious diseases. Early diagnosis of tuberculosis is by chest X-Ray, sputum examination, culture and nucleic acid amplification. Chest X-Ray findings are not very specific, sputum examination and culture take many days thus delaying the diagnosis. CT scan is very fast, non-invasive and accurate. It can diagnose the cause of unexplained cough, chest pain, fever and other chest symptoms. Because of accuracy, high speed and better resolution, CT scan is the modality of choice for early detection of pulmonary TB. The aim of the study is to evaluate the role of CT and HRCT in pulmonary TB.METHODSIt is a cross sectional study conducted at Jawaharlal Nehru Institute of Medical Sciences from January 2016 to June 2016 in a series of cases sent for CT or HRCT using AQUILION, Toshiba 64 slice multi detector CT. All the data were entered in excel sheet and transferred to SPSS Version 2 and then analysed by using descriptive statistics like mean, standard deviation and percentage. Chi square test was used. p Value of <0.05 was taken as statistically significant.RESULTSAmong 358 cases, 49.7% (178 cases) were diagnosed as pulmonary tuberculosis. In cases diagnosed as pulmonary TB, 104 (58.4%) were male and 74 (41.7%) were female. Over 60 yrs. of age, 56.1% of the cases had TB with cavitary and parenchymal lesion, followed by TB with lung destruction & cicatrisation in 17.3% of the cases. In younger age group, 20 years and below, had TB with cavitary & parenchymal lesions in 75% of cases and TB with chronic empyema & fibrothorax in 25% cases. Incidence of TB in higher age groups was statistically significant (p<0.05).CONCLUSIONSCT and HRCT can diagnose different stages of pulmonary TB and any associated diseases. It helps in taking treatment decisions and preventing disease spread which is an important health issue. For early detection of pulmonary TB, CT and HRCT is a must for diagnosis.
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Background: Prior to surgery it is very important that the surgeon is fully aware, and he should have the clear picture as to the extent of the disease and the nature of the disease to give satisfactory surgical outcomes for the patient. HRCT (High resolution computed tomography) is one such guiding tool for the surgeon. The objective was to study usefulness of HRCT scan in attico-antral disease in depicting the status of the middle ear structures.Methods: A total of 30 patients were studied. HRCT temporal bone was performed by using SIEMENS EMOTION 16 slice CT machine in axial plane and coronal images were reformatted. Findings of HRCT temporal bone were recorded. Findings of mastoid exploration surgery were recorded. Report of HRCT of temporal bone was correlated with surgical findings and tabulated using percentages.Results: Surgery showed cholesteatoma in 26 (86.6%) patients. Epitympanum was involved in 29 (96.6%) patients in HRCT and 30 (100%) patients at surgery. Extension beyond middle ear cleft was seen in 4 (13.3%) patients in HRCT and 5 (16.6%) patients at surgery. Tympanic segment of facial canal was the most commonly involved, showing erosion in 10 (33.3%) patients in HRCT and 12 (40%) patients at surgery. Lateral SCC was the most commonly involved in bony labyrinth seen in 4 (13.3%) patients in both HRCT and surgery. Erosion of dural plate was seen in 6 (20%) patients in HRCT whereas 9 (30%) patients showed dural plate erosion at surgery.Conclusions: HRCT of temporal bone plays a promising role in pre-operative assessment of cholesteatoma as it depicts the extent of the disease and integrity of most of the middle ear structures.
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Objective: To describe the characteristics of the clinical presentation, diagnosis, surgical methods, and outcomes of patients with otogenic cerebrospinal fluid (CSF) leakage secondary to congenital inner ear dysplasia. Methods: A retrospective review was performed of 18 patients with otogenic CSF leakage secondary to inner ear dysplasia who underwent surgery in our group from 2007 to 2017 and had a follow-up of at least 4 months. The average length of follow-up was three years. The characteristics of the clinical presentations of all patients, such as self-reported symptoms, radiographic findings, surgical approaches and methods of repair, position of the leakage during surgery, and postoperative course, including the success rate of surgery, are presented. Results: The patients presented mostly with typical symptoms of meningitis, severe hearing impairment, and CSF otorrhea or rhinorrhea. All 18 patients had at least one previous episode of meningitis accompanied by a severe hearing impairment. The preoperative audiograms of 17 patients showed profound sensorineural hearing loss, and one patient had conductive hearing loss. Twelve patients presented with an initial onset of otorrhea, and two had accompanying rhinorrhea. Six patients complained of rhinorrhea, two of whom were misdiagnosed with CSF rhinorrhea and underwent transnasal endoscopy at another hospital. High-resolution computed tomography (HRCT) images can reveal developments in the inner ear, such as expansion of a vestibular cyst, unclear structure of the semicircular canal or cochlea, or signs of effusion in the middle ear or mastoid, which strongly suggest the possibility of CSF otorrhea. The children in the study suffered more severe dysplasia than adults. All 18 patients had CSF leakage identified during surgery. The most common defect sites were in the stapes footplates (55.6%), and 38.9% of patients had a leak around the oval window. One patient had a return of CSF otorrhea during the postoperative period, which did not re-occur following a second repair. Conclusions: CSF otorrhea due to congenital inner ear dysplasia is more severe in children than in adults. The most common symptoms were meningitis, hearing impairment, and CSF otorrhea or rhinorrhea. HRCT has high diagnostic accuracy for this disease. The most common fistula site was around the oval window, including the stapes footplates and the annular ligament.
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OBJECTIVE@#To describe the characteristics of the clinical presentation, diagnosis, surgical methods, and outcomes of patients with otogenic cerebrospinal fluid (CSF) leakage secondary to congenital inner ear dysplasia.@*METHODS@#A retrospective review was performed of 18 patients with otogenic CSF leakage secondary to inner ear dysplasia who underwent surgery in our group from 2007 to 2017 and had a follow-up of at least 4 months. The average length of follow-up was three years. The characteristics of the clinical presentations of all patients, such as self-reported symptoms, radiographic findings, surgical approaches and methods of repair, position of the leakage during surgery, and postoperative course, including the success rate of surgery, are presented.@*RESULTS@#The patients presented mostly with typical symptoms of meningitis, severe hearing impairment, and CSF otorrhea or rhinorrhea. All 18 patients had at least one previous episode of meningitis accompanied by a severe hearing impairment. The preoperative audiograms of 17 patients showed profound sensorineural hearing loss, and one patient had conductive hearing loss. Twelve patients presented with an initial onset of otorrhea, and two had accompanying rhinorrhea. Six patients complained of rhinorrhea, two of whom were misdiagnosed with CSF rhinorrhea and underwent transnasal endoscopy at another hospital. High-resolution computed tomography (HRCT) images can reveal developments in the inner ear, such as expansion of a vestibular cyst, unclear structure of the semicircular canal or cochlea, or signs of effusion in the middle ear or mastoid, which strongly suggest the possibility of CSF otorrhea. The children in the study suffered more severe dysplasia than adults. All 18 patients had CSF leakage identified during surgery. The most common defect sites were in the stapes footplates (55.6%), and 38.9% of patients had a leak around the oval window. One patient had a return of CSF otorrhea during the postoperative period, which did not re-occur following a second repair.@*CONCLUSIONS@#CSF otorrhea due to congenital inner ear dysplasia is more severe in children than in adults. The most common symptoms were meningitis, hearing impairment, and CSF otorrhea or rhinorrhea. HRCT has high diagnostic accuracy for this disease. The most common fistula site was around the oval window, including the stapes footplates and the annular ligament.
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Adolescent , Adult , Child , Child, Preschool , Humans , Infant , Middle Aged , Young Adult , Cerebrospinal Fluid Otorrhea/therapy , Ear, Inner/abnormalities , Retrospective StudiesABSTRACT
Background: Chronic Obstructive Pulmonary Disease (COPD) is defined as a preventable and treatable lung disease with some significant extra-pulmonary effects. Pulmonary component is characterized by airflow limitation that is not fully reversible, usually progressive and associated with an abnormal inflammatory response of the lung to noxious particles and gases. Elderly patients are more prone to COPD due to the reduction in the immune power along with the muscle weakness of the chest wall and bone weakness. Aim and objectives: To study the COPD in elderly with reference to HRCT chest and PFT, to study the pattern of pulmonary involvement in COPD in elderly. Materials and methods: It was Prospective observational study. Study population was elderly patients (age ≥60 years) detected having COPD (both in-patient and out-patient) attending MGM Hospital for treatment. Detailed history was taken from patient, particularly history of symptoms like fever, cough, shortness of breath, weight loss, night sweat etc. Thorough physical examination of all the systems with special emphasis on respiratory system was done. Results: Total 50 patients were enrolled in the study. Majority of the patients (44%) were in the age group of 60-70 years followed by 32% in the age groups of 70-80 years and 24% patients in the age group of >80 years. The mean age of the patients was 72.76±7.58 years. There was male preponderance (72%) in the study. Majority of the male patients were smokers (61%). Dyspnoea (76%), cough (68%), sputum production (64%) were the common symptoms. Centriacinar emphysema (34%) was mostly observed. FEV1/FVC ratio ranged from 38-89% (mean 62.9+/- 18.52%) preinhalation, ranged from 45% to 90% (mean 69.26±15.08) post-inhalation. Conclusion: HRCT showed regional assessment of compartment involved and has greater sensitivity than chest radiography in early diagnosis of emphysema.
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Objective To compare the consistency of temporal bone HRCT,tympanium drip method,impedance audiometry for eustachian tube function and exploratory surgery,and to determine the best method for evaluation of eustachian tube function.Methods The examination of the eustachian tube function were given on 68 cases of otitis media with the surgical indication by these three methods above-mentioned in turn.And then compare the evaluation results with the exploratory surgery.Results The count data matching test of temporal bone HRCT,tympanium drip method and impedance audiometry compare with surgery exploration results were κ =0.625,κ =0.472,κ =0.912,respectively,which were in general degree(κ≥0.4).It suggested that the three methods were reliable for evaluation of eustachian tube function.Conclusion Among these three methods,impedance audiometry is the most accurate one,and then temporal bone functional HRCT,the last one is tympanium drip,therefore,the method of impedance audiometry is promoted to evaluate the function of eustachian tube.
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AIM To explore the efficacy of Chenshi Qingfei Decoction (Pseudostellariae Radix,Ophiopogonis Radix,Adenophorae Radix,etc.) against rheumatoid arthritis and interstitial lung disease (RA-ILD).METHODS Based on Prednisolone,RA-ILD patients were randomly divided into control group and observation group by random number table and randomized block design.The observation group took Chenshi Qingfei Decoction.The treatment course was three months for both groups.Before the treatment,the activity of the disease (DAS28) was assessed and ESR,CRP,RF,CCP were measured.Before and after the treatment,high resolution-CT (HRCT) was conducted and graded,and symptoms and signs were graded.RESULTS After the treatment,the effective rate of cough,expectoration and breath hard in the syndromes of Chinese traditional medicine was 71％ in the observation group and 23％ in the control group (P ＜0.01).The effective rate of improved lung imaging by HRCT was 68％ in the observation group but 13％ in the control group (P ＜0.01).CONCLUSION Based on the immunosuppressive agents therapy in RA,Chenshi Qingfei Decoction can relieve clinical symptoms of cough,expectoration and breath hard,and reduce area and degree of interstitial lung disease by HRCT.
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Objective To discuss the clinical characteristic of middle ear malformation with cholesteatoma.Methods From September,2011 to November,2016,23 cases of middle ear malformation with cholesteatoma were collected.Their symptoms,ENT examination,temporal bone high resolution computed tomography (HRCT) and intraoperative findings were analyzed.Results All 23 patients had hearing loss.90.0％ patients had ear discharge and tinnitus.86.96％ patients had perforation in pars flaccida of tympanic membrane.95.7％ patients had poor mastoid gasification.73.9％ patients had undeveloped or dysplastic tympanic antrum.100％ patients had destruction of the ossicular chain.56.5％ patients had malformation of the ossicular chain.52.2％ patients had exposed facial nerve.30.4％ patients had hyperplasia of the attic bone.Conclusion The symptoms and physical examinations of middle ear malformation with cholesteatoma are the same as middle ear cholesteatoma.Poor mastoid gasification can usually be detected on temporal bone HRCT.The most common malformation is dysplastic tympanic antrum,followed by malformation of the ossicular chain,exposed facial nerve and hyperplasia of the attic bone.Temporal bone HRCT can indicate the malformation and destruction quite well.
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AIM To explore the efficacy of Chenshi Qingfei Decoction (Pseudostellariae Radix,Ophiopogonis Radix,Adenophorae Radix,etc.) against rheumatoid arthritis and interstitial lung disease (RA-ILD).METHODS Based on Prednisolone,RA-ILD patients were randomly divided into control group and observation group by random number table and randomized block design.The observation group took Chenshi Qingfei Decoction.The treatment course was three months for both groups.Before the treatment,the activity of the disease (DAS28) was assessed and ESR,CRP,RF,CCP were measured.Before and after the treatment,high resolution-CT (HRCT) was conducted and graded,and symptoms and signs were graded.RESULTS After the treatment,the effective rate of cough,expectoration and breath hard in the syndromes of Chinese traditional medicine was 71％ in the observation group and 23％ in the control group (P ＜0.01).The effective rate of improved lung imaging by HRCT was 68％ in the observation group but 13％ in the control group (P ＜0.01).CONCLUSION Based on the immunosuppressive agents therapy in RA,Chenshi Qingfei Decoction can relieve clinical symptoms of cough,expectoration and breath hard,and reduce area and degree of interstitial lung disease by HRCT.
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Background: The radiological diagnosis of tuberculosis is regarded as the most sensitive screening tool. The current study is undertaken to evaluate the chest X-ray and HRCT Chest as the tools to evaluate the active tubercular lesions in symptomatic and sputum positive patients. Aims and Objectives: The purposes of this study was to compare the diagnostic efficacy of radiographic and HRCT findings of pulmonary tuberculosis and to determine the radiologic features frequently seen in this disease. As complications of tuberculosis are frequent, correct diagnosis of tuberculosis is important. The purposes of this study is to summarize radiographic and CT findings of pulmonary tuberculosis. Methods: All Suspected patients referred for chest x ray and HRCT in radio diagnosis dept JNIMS were included in the study. Results: On chest radiography air-space consolidation was the most common parenchymal lesion, occurring in 160 patients (80%). Nodular lesions were found in 56 patients (28%), and, among them, ipsilateral or contralateral air-space consolidation was seen in 44 patients (22%).Conclusion: Since Diagnostic efficacy of HRCT is 91 %. Diagnostic efficacy of Chest X-Ray is 70.5 %. So diagnostic efficacy of HRCT is more than the Chest X-Ray.