ABSTRACT
The global population aging problem is increasingly serious.For this reason, WHO proposed the goal of "Healthy Ageing" in 2015, that is to maintain and develop the functional ability of the individuals in order to achieve happiness in old age.At the same time, WHO introduced the relationship between functional ability, intrinsic capacity and the surrounding environment in which older adults live and acquire assistance, providing a new way for solving population aging. "Decade of Healthy Ageing: Baseline Report" was published by WHO in January 2021.It took advantage of existing national studies on ageing in 42 countries to assess the global status of healthy ageing at the start of the decade.And then it outlooks ten years ahead, to 2030, what level we can achieve, and what needs to improve ten years from now.
ABSTRACT
La Universidad de los Andes, ha constituido un centro interdisciplinario pionero en Chile y América Latina, denominado Centro Integral para el Envejecimiento Feliz, especializado en investigación de intervenciones que contribuyan al bienestar integral de Personas Mayores (PM) en situación vulnerable. Se presenta el diseño de una intervención multidimensional, que incorpora evaluaciones, intervenciones integrales e interdisciplinarias mediante prácticas colaborativas entre docentes y estudiantes de distintas carreras de la Universidad, aplicadas en PM asistentes a los Centros Diurnos para Adultos Mayores de la Municipalidad de Puente Alto, Región Metropolitana; y la evidencia en la que se fundamentan sus componentes estratégicos de intervención
The Universidad de los Andes has established a pioneering interdisciplinary center in Chile and Latin America, called the Integral Center for Happy Aging, specialized in research on interventions that contribute to the integral well-being of Older People (PM) in vulnerable situations. The design of a multidimensional intervention is presented, which incorporates evaluations, comprehensive and interdisciplinary interventions through collaborative practices between teachers and students of different careers of the University, applied in PM attending the Day Centers for Older Adults of the Municipality of Puente Alto, region Metropolitan; and the evidence on which its strategic components of intervention are based.
Subject(s)
Humans , Aged , Healthy Aging , Patient Care Team , Quality of Life , Geriatric Assessment , Comprehensive Health CareABSTRACT
@#Globally, there is an increase in older people. Clinicians, particularly primary care physicians, will need to equip themselves with knowledge and have a general approach for management of older people. In this paper, the following geriatric principles and concepts are covered: the trajectory of illness and the life course approach, multifactorial diagnoses and attributable risk, and comprehensive geriatric assessment. The illness trajectory concept enables clinicians to recognize where the patient is at, predict their likely prognosis and offer appropriate treatment decisions, balanced between aggressive curative intent and symptomatic management. The life course approach provides a model for planning intervention, which usually needs cooperation with other specialties. It is a worthwhile reminder for clinicians that older people tend to present with atypical symptoms, with multiple contributing factors towards their illness. Comprehensive geriatric assessment enables the clinician to gather sufficient information to complete clinical decision making for older people.
ABSTRACT
Human existence and their health rely on their intellectual interactions with ecosystem which eventually accompanies brilliant technological innovations. At par with the technological progress, humans also have been facing several intimidating communicable and non-communicable diseases. Amidst such disease threats, humans have discovered multiple ways to uplift the average life span all over the globe but still not up to the fitness benchmarks of healthy ageing trajectory. COVID-19 has specifically revealed the fragility of humans as they continue succumbing exponentially to the interactions of this communicable disease with their existing non-communicable diseases like hypertension, cardiac pathology and diabetes. In human evolution, the COVID-19 pandemic could be the most perfect synapse or intersection of non-communicable diseases with this transmissible disease leading to a situation that can be even named as “Global Medical Stampede” characterized by sudden increase in the number of patients requiring life-saving procedures for which there is lack of adequate manpower and technological support in health care system. This whole chaotic scenario could easily trigger acute psychological and physiological stress primarily caused by fear among the public favoring the frightening consequences of the pandemic. This article aims to suggest refinement in public health paradigms to enable preparations to face such disease threats from the immediate future without further procrastination.
ABSTRACT
With the worsening of population ageing in China, the life quality of the elderly is deeply affected by comorbidity, disability, dementia and psychological problems. In China, great achievements have been made in the research of healthy ageing, but due to limitations in research hypothesis, sample size, study design and quality of follow-up, the research findings are insufficient to provide high-quality evidence chain or can’t be adopt in health guidelines or standards for the elderly in China, especially the oldest-old. In this special issue, the team of Healthy Aging and Biomarkers Cohort Study reported a series of new findings on health pattern of the elderly, influencing factors and biomarkers in healthy ageing research to provide more comprehensive scientific evidences for health service and to support scientific implementation of health promotion program for the elderly and promote healthy ageing.
ABSTRACT
With the worsening of population ageing in China, the life quality of the elderly is deeply affected by comorbidity, disability, dementia and psychological problems. In China, great achievements have been made in the research of healthy ageing, but due to limitations in research hypothesis, sample size, study design and quality of follow-up, the research findings are insufficient to provide high-quality evidence chain or can't be adopt in health guidelines or standards for the elderly in China, especially the oldest-old. In this special issue, the team of Healthy Aging and Biomarkers Cohort Study reported a series of new findings on health pattern of the elderly, influencing factors and biomarkers in healthy ageing research to provide more comprehensive scientific evidences for health service and to support scientific implementation of health promotion program for the elderly and promote healthy ageing.
ABSTRACT
BACKGROUND: People who were born in different years, that is, different birth cohorts, grow in varying socio-historical and dynamic contexts, which result in differences in social dispositions and physical abilities. METHODS: This study used age-period-cohort analysis method to establish explanatory models on healthcare expenditure in Korea reflecting birth cohort factor using intrinsic estimator. Based on these models, we tried to investigate the effects of ageing population on future healthcare expenditure through simulation by scenarios. RESULTS: Coefficient of cohort effect was not as high as that of age effect, but greater than that of period effect. The cohort effect can be interpreted to show ‘healthy ageing’ phenomenon. Healthy ageing effect shows annual average decrease of −1.74% to 1.57% in healthcare expenditure. Controlling age, period, and birth cohort effects, pure demographic effect of population ageing due to increase in life expectancy shows annual average increase of 1.61%–1.80% in healthcare expenditure. CONCLUSION: First, since the influence of population factor itself on healthcare expenditure increase is not as big as expected. Second, ‘healthy ageing effect’ suggests that there is a need of paradigm shift to prevention centered-healthcare services. Third, forecasting of health expenditure needs to reflect social change factors by considering birth cohort effect.
Subject(s)
Cohort Effect , Cohort Studies , Delivery of Health Care , Forecasting , Health Expenditures , Korea , Life Expectancy , Methods , Parturition , Population Dynamics , Social ChangeABSTRACT
Ageing is the major biomedical challenge of our society, considered as a progressive and irreversible set of structural and functional changes for a living organism, in relation with both genes and environmental factors. The percentage of elderly people and the incidence of age-related diseases such as cardio-vascular diseases, cancer and neurodegenerative diseases are main concerns for many scientists from worldwide. <BR> Discovering the biological basis of ageing is one of the greatest remaining challenges for science. Findings from model organisms have revealed that ageing is a surprisingly modifiable process that can be manipulated by both genetic and environmental factors. <BR> One well-studied dietary manipulation of ageing is caloric restriction, which consists of restricting the food intake of organisms without triggering malnutrition and has been shown to retard ageing in model organisms. Ageing is intrinsically complex, being driven by multiple causal mechanisms. Each mechanism tends to be partially supported by data indicating that it has a role in the overall cellular and molecular pathways underlying the ageing process. Pharmacological intervention to decelerate ageing and age-related diseases is highly attractive because it would target all the population during many years. If successful, healthy ageing therapy will be more efficient in reducing mortality than to fight separately each age-related disease. Research on healthy ageing interventions has evolved along the main theories of ageing.<BR> Caloric restriction is already being used as a paradigm for developing compounds that mimic its life-extension effects and might therefore have therapeutic value. The potential for further advances in this field is immense; hundreds of genes in several pathways have recently emerged as regulators of ageing and caloric restriction in model organisms. Some of these genes, such as IGF1R and FOXO3, have also been associated with human longevity in genetic association studies. The parallel emergence of network approaches offers prospects to develop multitarget drugs and combinatorial therapies. Understanding how the environment modulates ageing-related genes may lead to human applications and disease therapies through diet, lifestyle, or pharmacological interventions. Unlocking the capacity to manipulate human ageing would result in unprecedented health benefits. Currently, health is understood as the removal of diseases in a defensive manner to the pathological process and with higher costs. Would be more effective the maintenance of health through prevention mechanisms identified by modern science. The study of the mechanisms by which various natural or health factors can influence the ageing process positively or negatively opens the path to design and obtain new products for the benefit of elderly people to maintain health for a long time and enabling a socially active role.<BR> Combining the balneotherapy with using healthy-ageing products, provides a significant advantage and represents the sustainability of the research in the context of which spas are the ideal place for the application of new treatments. Peloids and plants, used in balneotherapy, in the treatment of various rheumatic, endocrine, dermatological or gynecological diseases, because of many biological, biochemical, physical, chemical and physico-chemical actions that have in the body - represent the support for the design of new geroprotectives.
ABSTRACT
Ageing is the major biomedical challenge of our society, considered as a progressive and irreversible set of structural and functional changes for a living organism, in relation with both genes and environmental factors. The percentage of elderly people and the incidence of age-related diseases such as cardio-vascular diseases, cancer and neurodegenerative diseases are main concerns for many scientists from worldwide. Discovering the biological basis of ageing is one of the greatest remaining challenges for science. Findings from model organisms have revealed that ageing is a surprisingly modifiable process that can be manipulated by both genetic and environmental factors. One well-studied dietary manipulation of ageing is caloric restriction, which consists of restricting the food intake of organisms without triggering malnutrition and has been shown to retard ageing in model organisms. Ageing is intrinsically complex, being driven by multiple causal mechanisms. Each mechanism tends to be partially supported by data indicating that it has a role in the overall cellular and molecular pathways underlying the ageing process. Pharmacological intervention to decelerate ageing and age-related diseases is highly attractive because it would target all the population during many years. If successful, healthy ageing therapy will be more efficient in reducing mortality than to fight separately each age-related disease. Research on healthy ageing interventions has evolved along the main theories of ageing. Caloric restriction is already being used as a paradigm for developing compounds that mimic its life-extension effects and might therefore have therapeutic value. The potential for further advances in this field is immense; hundreds of genes in several pathways have recently emerged as regulators of ageing and caloric restriction in model organisms. Some of these genes, such as IGF1R and FOXO3, have also been associated with human longevity in genetic association studies. The parallel emergence of network approaches offers prospects to develop multitarget drugs and combinatorial therapies. Understanding how the environment modulates ageing-related genes may lead to human applications and disease therapies through diet, lifestyle, or pharmacological interventions. Unlocking the capacity to manipulate human ageing would result in unprecedented health benefits. Currently, health is understood as the removal of diseases in a defensive manner to the pathological process and with higher costs. Would be more effective the maintenance of health through prevention mechanisms identified by modern science. The study of the mechanisms by which various natural or health factors can influence the ageing process positively or negatively opens the path to design and obtain new products for the benefit of elderly people to maintain health for a long time and enabling a socially active role. Combining the balneotherapy with using healthy-ageing products, provides a significant advantage and represents the sustainability of the research in the context of which spas are the ideal place for the application of new treatments. Peloids and plants, used in balneotherapy, in the treatment of various rheumatic, endocrine, dermatological or gynecological diseases, because of many biological, biochemical, physical, chemical and physico-chemical actions that have in the body - represent the support for the design of new geroprotectives.