ABSTRACT
Autoimmune hemolytic anemia is a disease characterized by destruction of red blood cells (RBC) and anemia, caused by production of antibodies released against the body’s own RBCs. While this condition is more commonly idiopathic, it may accompany autoimmune diseases as well. Cold agglutinin disease (CAD) is a rare subtype of acquired autoimmune hemoliytic anemia, however, is an idiosyncratic clinical and pathological terminology, usually seen in older ages. This condition is caused by IgM antibodies called “cold agglutinins” formed against I antigens on RBC membranes which cause agglutination of RBCs at lower temperatures. In this case, a 56 year old male patient who was diagnosed with CAD secondary to Epstein-Barr virus (EBV) infection is being presented.
ABSTRACT
Este trabalho visa determinar prevalências de deficiência de ferro e vitamina A em crianças e adolescentes atendidos por equipe de Saúde da Família de Itajaí (SC) e avaliar relações entre o estado de ferro e o retinol sérico. Realizou-se um censo nutricional das famílias cadastradas. Coletaram-se dados socioeconômicos e demográficos. Avaliou-se a concentração de hemoglobina, hematócrito, ferro e retinol séricos. Participaram do estudo 31 das 156 famílias cadastradas. Apenas 39,1 por cento das crianças e 62,0 por cento dos adolescentes coletaram amostras sanguíneas. A renda média per capita foi 1,68±1,00 salários mínimos. Nenhum dos pais ou mães era analfabeto. Residiam em domicílio próprio 80,6 por cento das famílias. Todos os domicílios apresentavam esgoto e abastecimento de água por rede pública e 87,1 por cento eram de alvenaria. Diagnosticou-se deficiência de ferro em 16,7 por cento das crianças e 19,3 por cento dos adolescentes, e deficiência de vitamina A em apenas uma criança. Observaram-se correlações significativas para o ferro e retinol séricos entre crianças e entre adolescentes para a concentração de hemoglobina, hematócrito e retinol sérico. Encontraram-se prevalências leves de deficiência de ferro e vitamina A, possivelmente devido às características socioeconômicas e demográficas.
The objective of this article is to determine prevalence of iron and vitamin A deficiencies among children and adolescents attended by a Family Health Strategy team in Itajaí, Santa Catarina State, and to assess relations between iron status and serum retinol. A nutritional census of the families was carried out. Socioeconomic and demographic data were collected. Hemoglobin concentration, hematocrite, serum iron and retinal were determined. Thirty-one out of the 156 enrolled families participated in the study. Only 39.1 percent of the children and 62.0 percent of the adolescents had their blood samples collected. Mean per capita income was 1.68±1.00 minimum wages. None of the parents was illiterate and most families (80.6 percent) owned their homes. All homes had public sewage and water supply, and 87.1 percent were made of brickwork. Iron deficiency was diagnosed in 16.7 percent of the children and 19.3 percent of the adolescents. Only one child had vitamin A deficiency. Significant correlations were found between serum iron and retinol among children, and among adolescents between serum retinol and hemoglobin concentration and hematocrite. We found mild prevalences of iron and vitamin A deficiencies, possibly due to the socioeconomic and demographic characteristics.