ABSTRACT
Introduction: Hyperglycemia as assessed by hemoglobin A1c (HbA1c) may be an important biomarker in predicting wound healing rate in diabetic patients. Thus, the present study also intended to relate the HbA1c levels to wound healing in diabetic patients. Materials and Methods: A total of 100 diabetic patients with foot ulcers of variable sizes were included in the study and were assigned into two groups based on HbA1c levels. Mean area, length, and width of the ulcer were measured at baseline and during next subsequent visits in either group. Results: Mean area, length, and width of the ulcer at baseline did not show any signifi cant difference, whereas a statistically signifi cant (p < 0.01) difference was observed in mean measurement change per day between Groups A and B patients. Conclusion: This study suggests that slower wound healing is associated with increased HbA1c levels and can be considered as an independent biomarker in assessing wound healing in patients with diabetic foot ulcer.