ABSTRACT
Stevens-Johnson syndrome is an acute devastating condition which is related to certain drugs or infections. This syndrome involves multiple organs such as mucocutaneous, respiratory, occular and gastrointestinal systems. Patients who have underlying immunologic diseases are thought to be more susceptible. In lots of case reports and studies, more than 100 drugs have been implicated as causes of Stevens-Johnson syndrome or toxic epidermal necrolysis, but not so much as in Chinese Herb medications. Recently, we have experienced a patient with Stevens-Johnson syndrome after taking herb medicine and diagnosed as SLE during evaluation and treatment. We report this patient with a brief review of literatures.
Subject(s)
Humans , Asian People , Immune System Diseases , Lupus Erythematosus, Systemic , Stevens-Johnson SyndromeABSTRACT
Cryptococcosis is a disease caused by the Cryptococcus neoformans, occcuring most frequently in immunocompromised hosts. Cutaneous involvement is seen in 10-15 % of disseminated cases and its manifestation is variable. A 52 year old man presented with a subcutaneous neck mass and severe headache which had lasted for 2 months and 1 month respectively. Initially cutaneous involvement was monomorphic and localized and a CSF study failed to reveal any organisms. After several weeks of herb medication, however, multiple skin lesions occurred with varied morphology and a CSF study confirmed cryptococcosis by culture. The Urine cortisol was markedly elevated, suggesting an exogenous intake of steroid.
Subject(s)
Humans , Middle Aged , Cryptococcosis , Cryptococcus neoformans , Headache , Hydrocortisone , Immunocompromised Host , Neck , SkinABSTRACT
We reoport a case of multiple basal cell carcinoma in a 51-year-old male who have taken a herb medication for right hemiplegia during 30 years. The patient had a 15-year history of the black colored, ulcerated nodules on left forehead and erythematous, protruded masses on back. Also, he had a 6-year history of black colored, ulcerated nodules on right temporal area of scalp and brownish, flat plaques on anterior chest, Biopsy specimens from lesions revealed typical histopathologic findings of the basal cell carcinoma. Wide excision with graft was done. One year later, he was expired due to lung carcinoma.