ABSTRACT
Objective:To investigate the effects of femtosecond laser assistcataract extraction on the levels of inflammatory factors in aqueous humor, corneal perception and high order aberration.Methods:Forty-eight patients (56 eyes) undergoing cataract surgery in the Shouguang People′s Hospital from June 2018 to February 2020 were enrolled in this study, and they were divided into observation group (24 patients and 27 eyes, femtosecond laser cataract phacoemulsification) and control group (24 patients and 29 eyes, coaxial microincision phacoemulsification) by random number table method. The levels of prostglndin E2 (PGE2), interleukin (IL)-6 and IL-1β in aqueous humor were detected before and after operation. Upper corneal and central corneal perception thresholds were recorded before surgery, 7 d after surgery, 1 month after surgery and 3 months after surgery. High order aberrations of the whole eye and cornea at 4mm pupil diameter before and after operation were recorded.Results:After operation, the levels of PGE2, IL-6 and IL-1β in aqueous humor in the observation group were lower than those in the control group: (45.62 ± 5.71) ng/L vs. (63.65 ± 5.62) ng/L, (15.25 ± 3.21) ng/L vs. (24.59 ± 6.13) ng/L, (17.16 ± 1.28) ng/L vs. (25.74 ± 4.62) ng/L, the differences were statistically significant ( P<0.05). The upper and central corneal perception threshold of observation group after operation for 7 d were higher than those in the control group: 4.55 ± 0.50 vs. 4.20 ± 0.33, 5.68 ± 0.49 vs. 5.52 ± 0.45, the differences were statistically significant ( P<0.05). The indexes of high order aberration of the whole eye decreased in the two groups ( P<0.05), while the indexes of cornea did not change significantly. The indexes of high order aberration of the whole eye and cornea between before and after surgery between the two groups had no significant differences ( P>0.05). Conclusions:Femtosecond laser assist cataractextraction can relieve inflammation, reduce the whole eye high order aberration, but not affect the cornea, and can improve corneal perception.
ABSTRACT
Implantable collamer lens(ICL)and toric ICL(TICL)are clinically common types of posterior chamber phakic intraocular lenses, they are mainly used to correct high myopia and low-to-moderate myopia of eyes whose corneal conditions are not suitable for corneal laser surgery. Accurate preoperative measurement, safe intraoperative implantation and appropriate postoperative location of lenses are critical to ensure the outcome of ICL implantable, and the appearance of V4c ICL with a central hole ensures the safety of this surgery to a greater extent. However, the intraocular position of both ICL and TICL is not invariable. Some studies have shown that the vault has a trend of decreasing year by year after ICL surgery, but its reason is unknown. And spontaneous rotation may occur after the TICL surgery, thereby causing visual loss, which is one of the main causes of TICL replacement. And postoperative changes in the position of the central hole also need attention. In addition, the visual quality of the operated eye will change after ICL/TICL implantation, but whether the change of intraocular positions of implanted lenses will affect the postoperative visual quality is also a problem that needs to be paid attention to and explored. Therefore, this paper reviewed the postoperative changes in vault, TICL axis, position of the central hole and their causes, as well as the effects of these changes on postoperative visual quality, offering valuable clinical guidance for accurate preoperative selection of ICL/TICL and surgical design, so as to improve the effectiveness and stability of ICL implantation in correction of myopic refractive error.
ABSTRACT
@#AIM:To observe the therapeutic effects of standard laser in situ keratomileusis(LASIK), wavefront-guided LASIK(WF-LASIK)and small incision lenticule extraction(SMILE)on refractive errors. <p>METHODS: This study retrospectively analyzed 97 patients(194 eyes)with refractive errors admitted to the hospital between March 2020 and March 2021. They were divided into LASIK group(28 cases, 56 eyes), WF-LASIK group(32 cases, 64 eyes)and SMILE group(37 cases, 74 eyes)according to the surgical method. The uncorrected visual acuity(UCVA), diopter, high-order aberrations, tear film break-up time(BUT)and tear secretion function(SⅠt)were observed before and after operation, and related complications were recorded. <p>RESULTS: The UCVA, spherical diopter, cylindrical lens diopter and spherical equivalent were similar in the 3 groups at 1 and 3mo after operation(all P>0.05). The spherical aberrations of LASIK group, WF-LASIK group, and SMILE group at 1 and 3mo after operation decreased in order(all P<0.05). The horizontal coma and vertical coma of LASIK group and SMILE group at 1 and 3mo after operation were greater than those of WF-LASIK group(all P<0.05). The total high order aberrations of LASIK group at 1 and 3mo after operation were significantly greater than those of the other two groups(all P<0.05). BUT and SⅠt of SMILE group at 1 and 3mo after operation were significantly better than those of the other two groups(all P<0.05), without significant difference between WF-LASIK group and LASIK group(all P>0.05). The total incidence rates of complications in the 3 groups were close(P>0.05). <p>CONCLUSION: All of LASIK, WF-LASIK and SMILE can improve vision of patients with refractive errors. However, patients treated with WF-LASIK have the best visual quality after operation, and those treated with SMILE can obtained better tear film stability after operation.
ABSTRACT
@#AIM: To compare the change of refractive power and corneal high-order aberrations after femtosecond laser-assisted excimer laser <i>in situ</i> keratomileusis(FS-LASIK)and FS-LASIK combined with accelerated corneal cross-linking(FS-LASIK Xtra)for high myopia correction, and to evaluate the early effects of two surgical methods to correct high myopia. <p>METHODS:Retrospective case-control study. Totally 42 patients(84 eyes)with high myopia underwent FS-LASIK Xtra and FS-LASIK in our hospital from April 2019 to April 2020 were followed up for 3mo, including 21 patients in each group(42 eyes). The uncorrected visual acuity(UCVA), spherical equivalent(SE), astigmatism and corneal high-order aberration of the two groups were analyzed and compared.<p>RESULTS: The UCVA of the FS-LASIK Xtra group was significantly lower than that of the FS-LASIK group at 1d after surgery(<i>P</i><0.01), there was no statistical difference in UCVA at the other time points after surgery between the two groups(<i>P</i>>0.05). The postoperative SE of the two groups was significantly lower than that before surgery, at 3mo after surgery, 38 eyes(90%)in the FS-LASIK Xtra group and 41 eyes(98%)in the FS-LASIK group had SE within ±1.00D. In both groups, 35 eyes(83%)had residual astigmatism within 0.50D after surgery. The total corneal high-order aberrations, spherical aberrations, coma and clover aberrations in the two groups were increased at 3mo after surgery, the total high-order aberration and clover aberration in the FS-LASIK Xtra group were greater than those in the FS-LASIK group(all <i>P</i><0.05).<p>CONCLUSION:FS-LASIK and FS-LASIK Xtra have good effectiveness and predictability in correcting high myopia in the early postoperative period, the total high-order aberrations of the cornea both increased in the early postoperative period, and the patients who underwent FS-LASIK Xtra were increased significantly.
ABSTRACT
@#AIM: To compare the difference between total and anterior corneal high-order aberrations(HOA)calculated based on the pupil diameters of 4.0mm and the actual measurements in different age groups.<p>METHODS:<i> </i>A cross sectional study. A Total of 100 subjects between March, 31<sup>th</sup> and May, 31<sup>th</sup> in 2019 were included. Their total corneal high-order aberrations(THOA)and anterior corneal high-order aberrations(AHOA)were detected on the basis of different machine-provided pupil diameters(2.0-7.0mm)and their photopic pupil diameters were recorded as measured pupil diameters in the room with normal illumination. THOA and AHOA based on the machine-measured pupil diameter was calculated through fitting curves, and compared to the THOA and AHOA at a theoretical 4mm pupil diameter.<p>RESULTS: The measured pupil diameter was negatively correlated with age(<i>r</i>= -0.587, <i>P</i><0.001). THOA and AHOA based on measured pupil diameter were both negatively correlated with age(<i>r</i>= -0.191, <i>P=</i>0.002; <i>r</i>=-0.181, <i>P</i>=0.004). At 4mm pupil diameter, THOA was positively correlated with age(<i>r</i>=0.282, <i>P</i><0.001), while there was no obvious correlation between AHOA and age. In 40-49, 60-69 and 70-79 years old groups, their THOA and AHOA at the measured pupil diameters were significantly lower than those at 4mm pupil diameter(<i>P</i><0.05), while their THOA were significantly higher than AHOA at the measured pupil diameters(<i>P</i><0.05). At 4mm pupil diameter, THOA were significantly lower than AHOA in 20-29 years old groups(<i>P</i>=0.006), but higher than AHOA in 60-69 years old groups(<i>P</i>=0.039). In the aged group(include 60-69 and 70-79 years old groups), the proportion of observed value of THOA ≥0.3μm at the measured pupil diameters were significantly lower than those at 4mm pupil diameter(χ<sup>2</sup>=4.300, <i>P</i>=0.038).<p>CONCLUSION: THOA and AHOA at the measured pupil diameters in the old subjects are significantly lower than those at 4mm pupil diameter, which could be ascribed to their relatively small actual mean pupil sizes. Our study suggested that the THOA rather than AHOA should be used for the selection of multifocal intraocular lens for cataract patients at measured pupil diameter, so that more aged patients will satisfy the inclusion criteria.
ABSTRACT
Objective To evaluate changes in corneal high-order aberrations after the wearing of orthokeratology contact lenses and to study the factors influencing those changes.Methods A series of case-observational method was used.Data on 46 right myopic eyes of 46 children fitted for orthokeratology were continuously collected from January to April 2018.The corneal morphology,the e values of the anterior and posterior corneal surface in the nasal,temporal,superior and inferior zones within 6 mm were measured with Pentacam Anterion Segment Analysis System before and one month after the wearing of orthokeratology contact lens.Zernike Analysis System was used to calculate the values of Z33,Z3-3,Z31,Z3-1,and Z40 on the anterior and posterior surfaces and on the total cornea within a diameter of 6 mm.This study conformed to the tenets of the Declaration of Helsinki.The study protocol was approved by the Ethics Committee of Baoding Yinghua Eye Hospital (No.YKLL-2018-1-01).Written informed consent was obtained from each child and their guardians prior to entering the study cohort.Results Compared to the values recorded prior to orthokeratology contact lens wear,the horizontal coma,vertical coma,and spherical aberration of the total cornea and anterior corneal surface were drifted positively after lens wear;the horizontal coma and spherical aberration of the posterior corneal surface were drifted negatively after lens wear;and the differences were statistically significant (all at P＜0.05).Before wearing orthokeratology contact lenses,eNf,eTf,eIf,eSf and eMf values were 0.580(0.450,0.670),0.455 (0.378,0.513),0.485 (0.268,0.553),0.665(0.578,0.740) and 0.505±0.015,respectively,and after wearing orthokeratology contact lenses,eNf,eTf,eIr,eSf and eMf values were 0.285(-0.635,0.665),-0.605 (-0.813,-0.335),-0.545 (-0.765,0.305),-0.335 (-0.705,0.423) and -0.247±0.058,respectively.Compared with the conditions prior to wearing orthokeratology contact lens,the anterior corneal surface in all parts changed from steep to fiat after lens wear,with statistically significant differences between them (all at P＜0.05).The results of multiple stepwise linear regression showed that after wearing orthokeratology contact lens,the spherical aberration of the total cornea was moderately negatively correlated with the corneal e value and the initial diopter (rs =-0.626,-0.450;both at P＜0.05),the horizontal coma of the total cornea was moderately negatively correlated with the temporal e value (rs =-0.391,P =0.004);the spherical aberration of the anterior corneal surface was moderately negatively correlated with the corneal e value and the initial diopter (rs =-0.612,-0.432;both at P＜0.05);the horizontal coma of the anterior corneal surface was moderately negatively correlated with the temporal e value (rs =-0.400,P =0.003);and the horizontal coma of the posterior corneal surface was negatively correlated with the horizontal coma of the anterior corneal surface (rs =-0.380,P =0.009).Conclusions The spherical aberration and coma of the total cornea and anterior corneal surface drift positively after wearing orthokeratology contact lens,and the spherical aberration and horizontal coma of the posterior corneal surface drift negatively.The refraction and deformation of the anterior surface of the cornea are important factors affecting variation in corneal high-order aberrations.
ABSTRACT
Objective@#To evaluate changes in corneal high-order aberrations after the wearing of orthokeratology contact lenses and to study the factors influencing those changes.@*Methods@#A series of case-observational method was used.Data on 46 right myopic eyes of 46 children fitted for orthokeratology were continuously collected from January to April 2018.The corneal morphology, the e values of the anterior and posterior corneal surface in the nasal, temporal, superior and inferior zones within 6 mm were measured with Pentacam Anterion Segment Analysis System before and one month after the wearing of orthokeratology contact lens.Zernike Analysis System was used to calculate the values of Z33, Z3-3, Z31, Z3-1, and Z40 on the anterior and posterior surfaces and on the total cornea within a diameter of 6 mm.This study conformed to the tenets of the Declaration of Helsinki.The study protocol was approved by the Ethics Committee of Baoding Yinghua Eye Hospital (No.YKLL-2018-1-01). Written informed consent was obtained from each child and their guardians prior to entering the study cohort.@*Results@#Compared to the values recorded prior to orthokeratology contact lens wear, the horizontal coma, vertical coma, and spherical aberration of the total cornea and anterior corneal surface were drifted positively after lens wear; the horizontal coma and spherical aberration of the posterior corneal surface were drifted negatively after lens wear; and the differences were statistically significant (all at P<0.05). Before wearing orthokeratology contact lenses, eNf, eTf, eIf, eSf and eMf values were 0.580(0.450, 0.670), 0.455(0.378, 0.513), 0.485(0.268, 0.553), 0.665(0.578, 0.740) and 0.505±0.015, respectively, and after wearing orthokeratology contact lenses, eNf, eTf, eIf, eSf and eMf values were 0.285(-0.635, 0.665), -0.605(-0.813, -0.335), -0.545(-0.765, 0.305), -0.335(-0.705, 0.423) and -0.247±0.058, respectively.Compared with the conditions prior to wearing orthokeratology contact lens, the anterior corneal surface in all parts changed from steep to flat after lens wear, with statistically significant differences between them (all at P<0.05). The results of multiple stepwise linear regression showed that after wearing orthokeratology contact lens, the spherical aberration of the total cornea was moderately negatively correlated with the corneal e value and the initial diopter (rs=-0.626, -0.450; both at P<0.05), the horizontal coma of the total cornea was moderately negatively correlated with the temporal e value (rs=-0.391, P=0.004); the spherical aberration of the anterior corneal surface was moderately negatively correlated with the corneal e value and the initial diopter (rs=-0.612, -0.432; both at P<0.05); the horizontal coma of the anterior corneal surface was moderately negatively correlated with the temporal e value (rs=-0.400, P=0.003); and the horizontal coma of the posterior corneal surface was negatively correlated with the horizontal coma of the anterior corneal surface (rs=-0.380, P=0.009).@*Conclusions@#The spherical aberration and coma of the total cornea and anterior corneal surface drift positively after wearing orthokeratology contact lens, and the spherical aberration and horizontal coma of the posterior corneal surface drift negatively.The refraction and deformation of the anterior surface of the cornea are important factors affecting variation in corneal high-order aberrations.
ABSTRACT
@#AIM: To investigate the stability of ICL V4c for moderate and high myopia and its effect on high order aberrations.<p>METHODS: The differences of uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA), spherical equivalent(SE), cylinder equivalent(CE), intraocular pressure(IOP), corneal endothelial cell count, total high order aberration(RMS), spherical aberration, vertical coma, horizontal coma, coma were compared among high myopia patients who treated with ICL V4c intraocular lens implantation(research group: 17 cases, 34 eyes)and femtosecond small incision matrix lens extraction(SMILE)(control group: 18 cases, 34 eyes)before operation(T0), 1d after operation(T1), 1wk after operation(T2), 1mo after operation(T3), 3mo after operation(T4)respectively.<p>RESULTS: SE and CE in research group were higher than those in control group at T3-T4(<i>P</i><0.05), RMS of higher order aberration and coma at T2-T4 were lower than those in control group(<i>P</i><0.05), spherical aberration and horizontal coma at T4 were lower than those in control group(<i>P</i><0.05).<p>CONCLUSION: ICL V4c implantation is stable in the correction of moderate and high myopia, and has little effect on high order aberration.
ABSTRACT
PURPOSE: To investigate changes in ocular high-order aberrations (HOAs) resulting from phacotrabeculectomy and phacoemulsification. METHODS: We retrospectively reviewed 38 eyes of 38 glaucoma and cataract patients who underwent mitomycin C (MMC) augmented trabeculectomy with phacoemulsification and 34 eyes of 34 cataract patients who underwent phacoemulsifiction. For all patients, we measured the best corrected visual acuity (BCVA), intraocular pressure (IOP), keratometry, and HOAs (iTrace, Tracey Technologies, Houston, TX, USA) both preoperatively and postoperatively. RESULTS: IOP was significantly decreased after surgery in the combined group (p < 0.001). Entire eye, coma-like, and spherical-like high-order aberrations from each entire eye, corneal aberrations, and internal-optics aberration were increased until after 2 weeks, which then decreased until 3 months after phacotrabeculectomy. In the phacoemulsification group, entire eye (each p = 0.006, p =0.006), coma-like (each p = 0.006 and p = 0.005), and spherical-like high-order aberrations (each p = 0.008, p = 0.005) from entire eye and internal-optics aberrations were decreased. CONCLUSIONS: After cataract surgery, entire eye, coma-like, and spherical-like high-order aberrations were significantly decreased while aberrations did not change after combined operation. These results suggest that a change in high-order aberrations of internal optics results in a decrease in postoperative HOAs. In addition, the baseline HOAs of the cataract group were higher than those of the combined surgery group, and the effect of trabeculectomy on HOAs may offset the impact of cataract surgery in the combined surgery group.
Subject(s)
Humans , Cataract , Glaucoma , Intraocular Pressure , Mitomycin , Phacoemulsification , Retrospective Studies , Trabeculectomy , Visual AcuityABSTRACT
AIM: To compare the change of visual quality of femtosecond-laser in situ keratomileusis ( FS-LASIK) and laser in situ keratomileusis ( LASIK) for myopia. METHODS: A retrospective case series. A total of 89 cases 178 eyes were chosen from Jan. 2014 to Dec. 2015. There were 46 cases (92 eyes) in FS-LASIK and 43 cases 86 eyes in LASIK. The visual acuity, refraction state, subjective visual quality score, high order aberration were measured at 6mo after surgery. RESULTS: All patients underwent operation smoothly, and no complication was observed during and after surgery; there was no statistically significant difference between two groups at visual acuity (P>0. 05). Postoperative diopter compared with preoperative expectations diopter difference is statistically significant between two groups (P CONCLUSION: Femtosecond laser corneal flap is more accurate and reliable and the discrete degree is smaller. It can make more thin corneal flap. Femtosecond laser disc of LASIK surgery compare with traditional mechanical plate layer knife following LASIK has better visual quality.
ABSTRACT
Background phacoemulsification combined with limbal relaxing incision (LRI) is reported to be effective for the management of coexisting cataract astigmatism,but the influence of after phacoemulsification with LRI on corneal high-order aberration is still rarely reported.Objective This study was to evaluate the effect of cataract surgery with LRI for preoperative astigmatism or on corneal high-order aberration.Methods A selfcontrolled serial cases observational study was designed.A total of 35 cataractous eyes of 35 patients with astigmatism ≥ 1.0 D before cataract surgery were enrolled in Tianjin Medical University Eye Hospital from August 2014 to April 2015 under the informed consent of patients.LRIs were performed on the eyes during the phacoemulsification and IOL implantation.The uncorrected visual acuity (UCVA),BCVA and optometry were recorded before operation and 1 day,1 week,1 month,3 months after operation.Pentacam was employed to measure the maximal and minimal diopters,astigmatism and high-order aberrations within 3 mm of the anterior corneal surface at above-mentioned time points.All the results were compared among different time points.The optometry outcomes and the anterior corneal surface astigmatism change were analyzed using vector analysis method.Results The UCVA was 0.34 ±0.22,0.38 ± 0.25,0.43±0.27,0.42±0.28 in 1 day,1 week,1 month and 3 months after operation,which was significantly higher than 0.08 ±0.09 before operation;and the BCVA was 0.54 ± 0.27,0.64 ± 0.29,0.67 ± 0.29,0.71 ± 0.32 in 1 day,1 week,1 month and 3 months after operation,showing a significant increase in comparison with 0.22±0.51 before operation(F=54.457,P=0.000;F =62.653,P =0.000).The refractive cylindrical error and corneal astigmatism were significantly decreased after operation in comparison with before operation (F =31.061,P =0.000;F =113.043,P=0.000).High order aberrations (HOA) at postoperative 1 day,1 week,1 month,3 months were all higher than those in preoperation (F =11.189,P =0.000) under the 4 mm pupil diameter.Compared with preoperation,the vertical coma,secondary vertical coma and three leaf clover were significantly increased(all at P＜0.05),but the horizontal coma and primary spherical aberration were not significantly changed (all at P＞0.05) under the 6 mm pupil diameter.Conclusions Phacoemulsification combined with LRI can reduce the corneal astigmatism effectively and steadily,and the increase of corneal aberrations does not affect visual acuity.
ABSTRACT
PURPOSE: To evaluate changes in corneal keratometry, high-order aberrations (HOAs), and anterior chamber parameters after trabeculectomy using Pentacam(R) (Oculus Inc., Dutenhofen, Germany). METHODS: Forty eyes of 40 patients who underwent limbal-based trabeculectomy or fornix-based trabeculectomy between July 2011 and May 2012 were retrospectively reviewed. Intraocular pressure (IOP), corneal keratometry, central corneal thickness, anterior chamber depth, anterior chamber volume, and HOAs were measured using Pentacam(R) preoperatively and at 3 months postoperatively. RESULTS: The mean age of patients who underwent trabeculectomy was 58.26 +/- 16.28 years. IOP showed significant decrease after surgery in both groups compared to preoperative values (p 0.05). CONCLUSIONS: Postoperative corneal keratometry and anterior chamber parameters did not change significantly compared to preoperative values in glaucoma patients after performing trabeculectomy. Most HOAs that affected quality of vision were not changed in the limbal-based trabeculectomy or fornix-based trabeculectomy.
Subject(s)
Humans , Anterior Chamber , Coma , Cornea , Glaucoma , Intraocular Pressure , Lotus , Retrospective Studies , TrabeculectomyABSTRACT
PURPOSE: To evaluate changes in corneal keratometry, high-order aberrations (HOAs), and anterior chamber parameters after trabeculectomy using Pentacam(R) (Oculus Inc., Dutenhofen, Germany). METHODS: Forty eyes of 40 patients who underwent limbal-based trabeculectomy or fornix-based trabeculectomy between July 2011 and May 2012 were retrospectively reviewed. Intraocular pressure (IOP), corneal keratometry, central corneal thickness, anterior chamber depth, anterior chamber volume, and HOAs were measured using Pentacam(R) preoperatively and at 3 months postoperatively. RESULTS: The mean age of patients who underwent trabeculectomy was 58.26 +/- 16.28 years. IOP showed significant decrease after surgery in both groups compared to preoperative values (p 0.05). CONCLUSIONS: Postoperative corneal keratometry and anterior chamber parameters did not change significantly compared to preoperative values in glaucoma patients after performing trabeculectomy. Most HOAs that affected quality of vision were not changed in the limbal-based trabeculectomy or fornix-based trabeculectomy.
Subject(s)
Humans , Anterior Chamber , Coma , Cornea , Glaucoma , Intraocular Pressure , Lotus , Retrospective Studies , TrabeculectomyABSTRACT
PURPOSE: To compare postoperative clinical outcomes between 2 types of 3-piece aspheric intraocular lenses. METHODS: Uncorrected visual acuity, best corrected visual acuity, total ocular and internal ocular aberration including higher-order aberrations and spherical aberration, and modulation transfer functions were compared 6 months after cataract surgery between eyes implanted with TECNIS ZA9003 (group 1) and HOYA PC-60AD (group 2) in 30 and 28 eyes, respectively, In addition, the differences between postoperative spherical equivalent and preoperative target refractive errors were analyzed. RESULTS: Clinical outcomes showed no significant differences between both groups including visual acuities, high order aberrations, and modulation transfer function. In both groups, postoperative refractive errors were more of a myopic state than preoperative estimated target refraction. The myopic refractive error between both groups showed no significant difference (-0.26 vs. -0.42 diopter, p = 0.75). CONCLUSIONS: The newly developed 3-piece aspheric IOL, HOYA PC-60AD shows similar clinical outcomes compared with the widely used 3-piece IOL TECNIS ZA9003.
Subject(s)
Cataract , Eye , Lenses, Intraocular , Refractive Errors , Visual AcuityABSTRACT
PURPOSE: To evaluate changes in corneal and ocular high-order aberration, ocular fatigue, and tear break-up time (TBUT) before and after playing computer games and the correlations among the variables. METHODS: Thirty-nine normal healthy subjects played computer games for 1 hour. Ocular fatigue was evaluated with a questionnaire, TBUT was measured with slit-lamp biomicroscopy, and high-order aberrations were measured with a KR-1W aberrometer (Topcon Medical System, Inc., Tokyo, Japan) in each subject before and after playing computer games. The right eye was used for statistical analyses. RESULTS: Subjective ocular fatigue (expressed as the interview score) increased from 4.23 +/- 5.35 to 12.05 +/- 8.68 after playing games (p < 0.001) and TBUT decreased from 8.03 +/- 6.43 sec to 4.90 +/- 3.31 sec (p < 0.001). Ocular high-order aberrations in the 4 mm and 6 mm zones were not significantly changed before and after playing games (p = 0.150, p = 0.202, respectively). However, corneal high-order aberrations in the 4 mm and 6 mm zones were significantly increased after playing computer games (p = 0.002, p = 0.002, respectively). Changes in TBUT, interview score, and corneal high-order aberration were not correlated with each other. CONCLUSIONS: Playing computer games increased corneal high-order aberrations as well as subjective ocular fatigue and TBUT.
Subject(s)
Eye , Fatigue , Surveys and Questionnaires , TokyoABSTRACT
PURPOSE: To study theeffect of micro incision (1.8 mm) and small incision (2.2 mm and 2.8 mm) coaxial phacoemulsification on surgically induced astigmatism (SIA) and high-order aberrations (HOA) of anterior and posterior corneal surface. METHODS: The present randomized clinical study included 32 eyes having a 1.8-mm, 38 eyes having a 2.2-mm, and 30 eyes having a 2.8-mm corneal incision. SIAs were measured at 1 and 3 months postoperatively. HOAs included coma, trefoil, and spherical aberration. The coma-root mean square (RMS) and trefoil-RMS were evaluated at 1 month after the cataract operation. RESULTS: Surgically induced astigmatisms were 0.41 +/- 0.30 diopter (D) in the 1.8-mm incision group, 0.47 +/- 0.21 D in 2.2-mm group and 0.71 +/- 0.50 D in the 2.8-mm group. The SIA of the 1.8-mm group was smaller than the other groups (p = 0.002). There was no statistically significant difference in coma, spherical aberration of the corneal anterior surface and trefoil, or spherical aberration of the posterior surface among the 3 groups at 1 month after surgery. CONCLUSIONS: Incision size contributes to postoperative corneal astigmatism. Phacoemulsification cataract surgery with less than 2.8-mm incision does not significantly influence the corneal aberrationsof anterior and posterior corneal surfaces.
Subject(s)
Astigmatism , Cataract , Coma , Eye , Lotus , PhacoemulsificationABSTRACT
PURPOSE: To investigate and compare the clinical outcomes of wavefront-guided LASIK performed by 2 different laser platforms. METHODS: A retrospective analysis of consecutive cases of eyes that underwent wavefront-guided LASIK by using the VISX S4 CustomVue system and the Zyoptix Z100 system advanced personalized mode. All procedures were performed by one surgeon. Fifty-six eyes of 36 patients were included. Of the 56 eyes, 30 eyes underwent LASIK by using the VISX S4 CustomVue system (CustomVue group), and other 26 eyes underwent LASIK by using the Zyoptix Z100 system (APT group). Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), manifest refraction, contrast sensitivity, total high order aberration (HOA), spherical aberration (SA) and Q-value were recorded preoperatively and at 1 week, 1 and 3 months postoperatively. RESULTS: There was no statistically significant difference between two groups in terms of preoperative UCVA, BCVA, manifest refraction, high order aberrations, Q-value and contrast sensitivity. Induced amount of SA was significantly lower in CustomVue group than in APT group (p = 0.02). CONCLUSIONS: Wavefront-guided LASIK performed by 2 different laser platforms caused clinically acceptable outcomes including good visual acuity and contrast sensitivity through 3 months. Furthermore, LASIK performed by VISX S4 CustomVue system caused less SA at three months after operation.
Subject(s)
Humans , Contrast Sensitivity , Dimaprit , Eye , Keratomileusis, Laser In Situ , Retrospective Studies , Visual AcuityABSTRACT
PURPOSE: To compare changes of anterior corneal aberration (Pentacam(R)) and ocular aberration (aberrometer, LADARWave(R)) after laser refractive surgery. METHODS: Sixty-six eyes underwent laser refractive surgery and were retrospectively reviewed. Anterior corneal aberration and ocular aberration were measured by Pentacam(R) and an aberrometer (LADARWave(R)) respectively. Changes of root mean square (RMS) values of coma, spherical aberration, and total high order aberration (HOA) were evaluated before, 1 month, and 3 months after surgery RESULTS: Ocular aberrations displayed low preoperative values, but after laser refractive surgery, anterior corneal aberration and ocular aberration increased equally. There were no statistically significant differences of internal optics aberration values (ocular aberration minus anterior corneal aberration) in coma, spherical aberration, and total HOA. Anterior corneal aberration and ocular aberration showed statistically significant correlations at 1 and 3 months after surgery. CONCLUSIONS: Internal optics aberration compensated the anterior corneal aberration effectively before surgery, but the increase of anterior corneal aberration after laser refractive surgery exceeded the compensation of internal optics. As a result, anterior corneal aberration and ocular aberration increased equally. The correlation between anterior corneal aberration and ocular aberration after surgery was statistically significant due to the increased proportion of anterior corneal aberration in ocular aberration.
Subject(s)
Adult , Humans , Cornea/physiopathology , Corneal Topography , Lasers, Excimer/therapeutic use , Myopia/surgery , Photography , Refraction, Ocular/physiology , Refractive Errors/physiopathology , Refractive Surgical Procedures , Retrospective StudiesABSTRACT
PURPOSE: To compare high order aberrations (HOA) among pseudophakic eyes with three different types of acrylic intraocular lenses (IOLs) and phakic eyes. METHODS: The ocular aberrations were measured within the central 4 mm pupil zone, using the Hartmann-Shack aberrometer in the eyes with acrylic IOLs, such as Acrysof(R) MA60BM, Acrysof(R) SA60AT, or Sensar(R) AR40e, at one month after uneventful cataract surgery and in the phakic eyes. Total HOA root-mean-square (RMS) value, coma, trefoil, and spherical aberration were compared among the groups. RESULTS: A total 49 pseudophakic and 18 phakic eyes were enrolled. Of the acrylic IOLs, Acrysof(R) MA60BMs (Alcon) were inserted in 16 eyes, Acrysof(R) SA60ATs (Alcon) in 16 eyes, Sensar(R) AR40es (Allergan Surgical) in 17 eyes. The average ages and pupil diameters among the four groups were not different (p=0.413, 0.797, respectively). The RMS values of total HOA, coma, and trefoil were not different among the groups (p=0.781, 0.370, 0.509, respectively), whereas the spherical aberration was significantly different among the four groups (p=0.033, Kruskal-Wallis test). There was no difference in the spherical aberration of the three acrylic IOL groups, but eyes with Acrysof(R) MA60BMs, Acrysof(R) SA60ATs had a larger spherical aberration than phakic eyes (p=0.040, 0.021, respectively, Mann-Whitney U test). CONCLUSIONS: There were no statistically significant differences in total HOA, coma, and trefoil among pseudophakias implanted with three different acrylic IOLs and phakic eyes. There was no difference in spherical aberration between the different IOL groups, but eyes with some acrylic IOLs had a larger spherical aberration than phakic eyes.
Subject(s)
Cataract , Coma , Lenses, Intraocular , Lotus , Pseudophakia , PupilABSTRACT
PURPOSE: We evaluate the clinical outcomes after wavefront-guided LASIK using the Fourier algorithm. METHODS: The uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), manifest refraction measured with auto refractometer, spherical aberration, coma, trefoil, total high order aberrations and contrast sensitivity of daytime and nighttime in 23 eyes of 13 patients who had undergone wavefront-guided LASIK using the Fourier algorithm preoperatively and at 1 day, 1 week, 1 month, 2 months and 6 months postoperatively. RESULTS In the wavefront-guided LASIK using the Fourier algorithm, the preoperative UCVA was 0.13+/-0.10 and increased to 1.02+/-0.29 (p=0.000) at 6 months postoperative, the postoperative spherical equivalent was -6.48+/-1.68D and 1.02+/-0.29 (p=0.000) at 6 months postopertive. The total high order aberration was 0.324+/-0.107 preoperative and 0.338+/-0.167 (p=0.810) at 6 months postoperative in wavefront-guided LASIK using the Fourier algorithm. Preoperative daytime contrast sensitivity increased preoperative from 0.75+/-0.24 to 1.11+/-0.35 (p=0.026) at 12 cpd, and that at 6-month preoperative increased from 1.05+/-0.26 to 1.41+/-0.41 (p=0.003) at 7.5 cpd and from 1.45+/-0.34 to 1.69+/-0.42 (p=0.028) at 4.8 cpd. CONCLUSIONS: The clinical outcomes of wavefront-guided LASIK using the Fourier algorithm after 6 months were stable visual acuity, no increase in high order aberration and no increase in contrast sensitivity.