Changes in the Contents of Water and Electrolytes in Cerebral Cortex of Rats at Simulated High Altitude of 6000m / 第三军医大学学报

Cerebral edema occurred in adult rats exposed to simulated high altitude of 6000m. Both sodium and water contents in cortex tissue of rats increased, which was a characteristic sign of cytotoxic brain edema. Our results support the hypothesis that acute mountain sickness results from cerebral edema because of high altitude hypoxia.