ABSTRACT
No abstract available.
Subject(s)
Animals , Rats , Dopaminergic Neurons , Parkinson Disease , TransplantationABSTRACT
21 albino rats were used. The origin of the noradrenergic (NA) fibers in the septum was studied with a simultaneously combined retrograde fluorescent tracing and histofluorescence method. The results revealed that the NA neurons projecting to the septum were in A_1, A_2 and A_6 groups. The projections of A_1 were bilateral, But A_2 and A_6 projected dominantly to the ipsilateral septum, with a few to the contralateral. Retrograde labeled NA cells were localized in the rostrodorsal part of A_6 group, and scattered over the whole rostrocaudal length of A_(1,2) groups. No labeling was seen in A_4 and A_7 groups. In five of the animals, retrograde labeled NA cells were occasionally observed in A_5 group. In addition, some scattered labeled non-NA neurons were seen in the raphe and the ventrolateral reticular formation of the rostral medulla.
ABSTRACT
The distribution and morphological characteristics of catecholamine(CA)-containing neurons in the human brain stem of 7-9-month-old fetuses were studied by using Faglu histofluorescence method. The distribution of the main CA groups is consistent with the data provided by the literature concerning human infant and adult except for the presence of numerous small premature-looking fluorescent cells in the fetal area postrema which is lacking in the human infant and adult. As compared with most studies of other animals, the CA neurons of the dorsocaudal extension of the locus coeruleus in human appear to be more extensive and do not close to the ependyma of the fourth ventricle. Moreover, the CA neuronal population in human midbrain become more hypertrophic and appear to be more complexly organized in comparison with those in animals.
ABSTRACT
The distribution and morphological characteristics of CA-containing cell bodies of diencephalon in 7-9monthold fetuses were studied by means of Faglu histofluoresccnce method. Although the general distribution of CA cell bodies in the human diencephalon observed in the present study is similar to that in other mammals, there are some significant differences. A great number of CA neurons occur within the lateroventral hypothalamic zone. There are more numerous larger CA neurons distributed outside the periventricular gray in human diencephalon.