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Objective To study the epidemiological characteristics of family cancer history in patients with nasopharyngeal carcinoma in Dongguan city. Methods A total of 240 patients with nasopharyngeal cancer treated in our hospital from January 2017 to January 2021 were selected for the investigation of family cancer history. The families of the patients were determined respectively, and the family cancer history of the first, second and third relatives was obtained. The incidence, population distribution and incidence factors were investigated and analyzed. Results A total of 7 918 primary, secondary and tertiary relatives of 240 cases were inquired. 188 cases were found to have cancer, including 118 cases of nasopharyngeal cancer and 70 cases of non-nasopharyngeal cancer (10 cases of digestive tract cancer, 18 cases of breast cancer, 20 cases of lymphoma and 22 cases of lung cancer). The incidence of familial cancer was higher in males (127/240) than in females (79/188). The main pathological type of family cancer was squamous cell carcinoma (109/188), accounting for 57.98%. Most of the patients in family cancer group were farmers (128/188), accounting for 68.09%; There was no significant difference in the prevalence of nasopharyngeal carcinoma and non-nasopharyngeal carcinoma in relatives of different genders (χ2=0.11, χ2=0.23, P>0.05). The incidence of cancer in first-degree relatives of different genders was higher than that in second-degree relatives, and the differences were statistically significant (χ2=4.26, χ2=5.62, P2 times per week), Epstein-Barr virus infection was significantly higher than that of the familial non-cancer group, the difference was statistically significant (χ2=6.57, χ2=10.59, P<0.05). Conclusions The incidence of cancer and nasopharyngeal cancer in first-degree relatives is significantly higher than that in second-level and third-level relatives. The occurrence of nasopharyngeal cancer is the result of the combined action of genetic factors and environmental factors. It is necessary to carry out health education for the families of nasopharyngeal cancer, Avoid eating and curing foods, and actively improve production and living environment, so as to reduce the incidence rate of nasopharyngeal carcinoma.
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Objective:To explore the effect of family history of cancer on clinical features and prognostic factors in nasopharyngeal car-cinoma (NPC) patients. Methods:The clinical data of 89 NPC patients with a family history of cancer and 388 NPC patients without a family history of cancer were retrospectively reviewed. Univariate and multivariate survival analyses were performed to identify possi-ble prognostic factors. Results:The clinical characteristics of NPC patients with and without family history of cancer were compared. The gender, age, TNM stage, pathological type, and hemoglobin radiotherapy concentration before treatment did not significantly dif-fer between the two groups (P>0.05). NPC patients with a family history of cancer had better 3-year overall survival than those with-out family history of cancer (91.6%vs. 85.5%), but no statistically significant difference was observed (P=0.211). Both univariate and multivariate analyses showed that T, N, and TNM stages were the important prognosis factors affecting 3-year overall survival (OS), progression free survival (PFS), and distant metastasis-free survival (DMFS) of NPC (P0.05). Conclusion:NPC patients with family history of cancer had better 3-year OS than those without family history of cancer, but no statistically significant observation was found. Large T stage or high lymph node stage contributed to poor survival of NPC. Family history of cancer had no significant in-fluence on the survival of NPC patients.
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PURPOSE: The aim of this study was to examine the health-related behaviors related to a family history of cancer (FHCA) among Korean women underwent cancer screening. MATERIALS AND METHODS: A total of 8,956 women who underwent cancer screenings during 2001-2011 at the National Cancer Center, Korea, were analyzed. The association between health-related behaviors and a FHCA were assessed using multivariate logistic regression. RESULTS: Compared to women with no FHCA, women with FHCA were more likely to smoke (adjusted odds ratio [aOR], 1.32; 95% confidence interval [CI], 1.06 to 1.65), to be exposed to passive smoking (aOR, 1.21; 95% CI, 1.15 to 1.65), and less likely to engage in regular exercise (aOR, 1.20; 95% CI, 1.01 to 1.41). Combined effects of selected health behaviors for FHCA were significant, although no statistically significant interactions were observed between selected health behaviors. Compared to women with no FHCA, women with FHCA were more likely to simultaneously smoke and be exposed to passive smoking (aOR, 1.65; 95% CI, 1.17 to 2.31) and to simultaneously smoke and be physically inactive (aOR, 1.62; 95% CI, 1.00 to 2.64). CONCLUSION: The study found that women with a FHCA exhibited unhealthy behaviors compared to women without FHCA. Higher emphasis on lifestyle modifications using a new standardized tool is strongly recommended for those with a FHCA, as well as individuals who are at high risk, together with their family members.
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Female , Humans , Early Detection of Cancer , Health Behavior , Korea , Life Style , Logistic Models , Mass Screening , Odds Ratio , Smoke , Tobacco Smoke PollutionABSTRACT
As campanhas de prevenção do câncer no Brasil são um aspecto importante da história do controle da doença. Os materiais produzidos no decorrer dessa história são uma rica fonte de documentos que merecem o olhar de profissionais de áreas como educação, comunicação, informação, saúde pública, história e hivulgação científica. Partindo desse pressuposto, analisam-se materiais de campanhas educativas a partir de distintos campos do conhecimento. As notas relatadas são fruto de análise preliminar de cartazes utilizados em campanhas. Este estudo foi realizado sob o enfoque da história da educação em saúde e será aprofundado nas próximas etapas da pesquisa.
Cancer prevention campaigns in Brazil are an important feature of the history of efforts to control this disease. The material produced down through this history offers a rich source of documents that merit the attention of professionals in such areas as education, communication, information, public health, history, and scientific educational outreach. Starting from this premise, I have analyzed education campaign material coming from different fields of knowledge. My notes are the result of a preliminary analysis of campaign posters from the perspective of the history of health education. This research will be further developed.
Subject(s)
Humans , History, 20th Century , Health Promotion/history , Neoplasms/history , Neoplasms/prevention & control , Brazil , Public Health/history , Health Education/history , Educational and Promotional MaterialsABSTRACT
Analisa ações de médicos ligados às iniciativas pública e privada e que colaboraram para a incorporação do combate ao câncer, na agenda das políticas públicas de saúde do governo federal, cristalizadas na criação do Serviço Nacional de Câncer em 1941. Objetiva também demonstrar que esse processo histórico se relaciona diretamente ao contexto internacional de intercâmbio científico entre o Brasil e os Estados Unidos, incentivado pela 'política da boa vizinhança', nos anos 1940. Aponta disputas políticas pela primazia da coordenação de ações de combate à enfermidade, no âmbito do poder central.
The article analyzes initiatives taken by physicians from both the private and public sectors who contributed to placing the fight against cancer on the federal government's agenda of public health policies, which became embodied in the 1941 creation of Brazil's National Cancer Service. The text also aims to show that this historical process was directly related to the international context of scientific exchange between Brazil and the United States that was encouraged under the Good-neighbor Policy of the 1940s. It calls attention to political disputes over the coordination of efforts to fight the disease at the federal level.
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Humans , History, 20th Century , Neoplasms/history , Neoplasms/prevention & control , United States , Brazil , Public Health/history , Natural History of Diseases , History, 20th Century , Researcher Exchange , Health Policy/historyABSTRACT
Background: In around 10 to 15% of all colorectal cancer (CRC) cases, a positive family history of colorectal cancer is observed . Although increased risk of colorectal cancer in individuals with a family history of the disease has been observed consistently in the past studies, limited information is available on colorectal cancer associated with family history in Iran. Aims : The purpose of this study is to define the risk of colorectal cancer associated with a family history of cancer. Setting and Design: The present study was designed as an unmatched case control study. The cases were 393 patients with histologically confirmed colorectal carcinomas and there were 393 controls, randomly selected from among the healthy participants in a health survey. Methods : The family history was extracted from a standard history form completed by the patient or from the record created by a health care provider. Statistical Analysis: Mantel-Heanszel Odds Ratio was computed for removing the confounding effect of age and sex. Results : A positive family history of cancer was reported by 36.4 and 24.4% among the cases and controls, respectively. Colorectal cancer risk increased two-fold in subjects who reported having first degree relatives with cancer. The adjusted odds ratio was 4.76, indicating that having a positive family history of colorectal cancer among relatives increased one's risk of colorectal cancer about 4.5-fold. Conclusion: According to our findings, a family history of cancer increased the risk of CRC. Due to this fact that there is no current colorectal cancer screening program in Iran, it is recommended that first degree relatives of patients with colorectal cancer should be considered as a priority group for screening programs.