ABSTRACT
In order to clarify the origin of Houzao, this paper summarizes and analyzes the related literatures, on-site investigation and experimental research results of Houzao. The results showed that Houzao coming from India is the gastric bezoars of Capra hircus. It is suggested that the name of the standard of imported Houzao should be changed to "Yangchangzao". At the same time, the local standards of Houzao should be abolished, and the standards of local processing procedures and the specifications of related Chinese patent medicines should be revised. In addition, according to literature research, the first detailed description of the origin and characters of Houzao may be Jie-sheng Shi's discussion in Shaoxing Medical Journal in 1920.
ABSTRACT
Objective To make a qualitative and a quantitative control on the Calculus Bovis in Houzao Niuhuang Powder.Methods Hyodeoxycholic acid and bilirubin in Calculus Bovis were separately identified by TLC,and the cholic acid content was determined by TLCS with the scan wavelength of ?s=380 nm,?R=650 nm.Results TLC can be used for the identification in-vitro cultured Calculus Bovis and artificial Calulus Bovis,the samples containing cultured Calulus Bovis showed the specific spots of bilirubin but no hyodeoxycholic acid spot while the samples containing artifical Calulus Bovis showed the hyodeoxycholic acid spot but no bilirubin spot.TLC-scanning can be used to measure the quantity of cholic acid,with the linear range being 0.2～1.8 ?g,average recovery rate of 99.5 %,and RSD being 3.3 %(n=6),and the results accorded with the criterion of the cultured Calculus Bovis in Chinese pharmacopoeia.Conclusion The methods can effectively control the quality of Calculus Bovis in Houzao Niuhuang Powder.