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Objective@#To investigate the awareness of human papillomavirus (HPV) vaccine knowledge among women in Hainan Province and the willingness to receive HPV vaccination among women and their daughters, so as to provide insights into HPV vaccine promotion and cervical cancer control. @*Methods@#Women aged 20 to 64 years who participated in the cervical cancer screening program in Hainan Province from July 2021 to February 2022 were enrolled, and participants' demographics, awareness of knowledge about HPV vaccine, and willingness to receive HPV vaccination among themselves and their daughters using a questionnaire survey. The factors affecting willingness to receive HPV vaccination were identified using a multivariable logistic regression model.@*Results@#A total of 4 300 questionnaires were allocated and 4 023 valid questionnaires were recovered, with an effective recovery rate of 93.56%. The respondents had a mean age of (35.52±6.48) years, and their daughters had a mean age of (8.93±4.83) years. There were 826 participants knowing HPV vaccine-related knowledge, with an awareness rate of 20.35%. The proportions of willingness to receive HPV vaccination were 75.07% among respondents and 71.36% among their daughters. Multivariable logistic regression analysis identified age (20 to <30 years, OR=1.474, 95%CI: 1.167-1.862; 30 to <40 years, OR=1.455, 95%CI: 1.199-1.765), urban-registered residence (OR=1.251, 95%CI: 1.016-1.541), monthly household income (3 000 to <5 000 Yuan, OR=1.568, 95%CI: 1.314-1.873; 5 000 Yuan and more, OR=1.231, 95%CI: 1.014-1.496), affordable fees for a single dose of HPV vaccination (100 to <500 Yuan, OR=1.358, 95%CI: 1.159-1.590; 500 Yuan and higher, OR=1.609, 95%CI: 1.188-2.180), and awareness of HPV vaccine-related knowledge (OR=4.473, 95%CI: 3.416-5.855) as factors affecting respondents' willingness to receive HPV vaccination, and participation in New Rural Cooperative Medical Insurance (OR=1.652, 95%CI: 1.087-2.511), affordable fees for a single dose of HPV vaccination (100 to <500 Yuan, OR=1.905, 95%CI: 1.633-2.221; 500 Yuan and higher, OR=1.683, 95%CI: 1.275-2.223), awareness of HPV vaccine-related knowledge (OR=3.625, 95%CI: 2.847-4.615), daughter's active request for HPV vaccination (OR=1.695, 95%CI: 1.293-2.222), and frequency of sexual health education for daughters (frequently, OR=2.142, 95%CI: 1.789-2.564; occasionally, OR=1.707, 95%CI: 1.416-2.059) as factors affecting the willingness to receive HPV vaccination among respondents' daughters. @*Conclusions@#The awareness of HPV vaccine-related knowledge is low among women aged 20 to 64 years in Hainan Province, and the women's and their daughters' willingness to receive HPV vaccination is associated with age, household registration, economic level, price of HPV vaccine and awareness of HPV vaccine-related knowledge.
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Objective@#To understand the behavioral characteristics of vaccination of human papillomavirus (HPV) vaccine based on diffusion of innovation theory, and to put forward suggestions for improving the vaccination willingness.@*Methods@#The women who had made an appointment or received at least one dose of HPV vaccine in two community health service centers with HPV vaccination qualification in Hangzhou were recruited by convenience sampling method. A questionnaire survey was conducted according to cervical cancer risk factors, HPV vaccine knowledge and the time of vaccination. The diffusion of HPV vaccination and the characteristics of vaccinees in different stages was analyzed.@*Results@#A total of 448 women, aged from 18 to 45 years old, with a median of 30.5 years old, were investigated. The spread of HPV vaccine were divided into five stages: April 2017 and before was the initial stage, with 8 leaders, accounting for 1.79%; October 2017 to February 2018 was the slowly rising stage, with 59 early vaccinees, accounting for 13.17%; April 2018 to April 2019 was the rising stage, with 160 most early vaccinees, accounting for 35.71%; May to August 2019 was the rapidly rising stage, with 170 most late vaccinees, accounting for 37.95%; September 2019 to the end of the survey was the standstill stage, with 51 laggards, accounting for 11.38%. All of the leaders had participated in cervical cancer screening, voluntarily vaccinated, and knew the susceptible population of cervical cancer, the targeted HPV types and the suitable population of vaccine. The median age of the first pregnancy was 27 years old. Six of them had three pregnancies. The early vaccinees and the most early vaccinees were recommended by doctors or friends to get HPV vaccine. The median age of first pregnancy was 26 and 28 years old, respectively. Their other characteristics were similar to those of the leaders. The characteristics of most late vaccinees were similar to those of the laggards. They were were mainly students who were recommended by their friends to receive HPV vaccination, did not participate in cervical cancer screening, did not know the susceptible population of cervical cancer, the targeted HPV types and the suitable population of vaccine.@*Conclusions@#People with high risk of HPV exposure, awareness of cervical cancer and screening are more likely to receive HPV vaccination at the early stage. It is necessary to strengthen the health education of HPV vaccination, and make full use of the influence of doctors and early vaccinees, which is helpful to promote the early vaccination of HPV vaccine among the right age population.
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Background: To have a successful cervical cancer control programme in developing countries, nursing staff must be aware of the facts about the disease preventive methods and the prophylactic human papilloma virus (HPV) vaccine. The aims of the present study were to assess knowledge of, attitudes toward and concerns to HPV vaccine among female Sikkimese nursing staff in India.Methods: Between April 2012 and February 2013, a pre-designed, pretested, self administered multiple responses questionnaire survey was conducted among female Sikkimese nursing staff in India.Results: Overall, 77.4% nursing staff responded that they had ever heard of a HPV vaccine. Trainee nurses were significantly more aware of the vaccine than regular working nurses. Actual knowledge of the vaccine was poor. Recommended age of HPV vaccination was aware by only 38.7% and only 30% nurses knew number of doses of vaccine, while over 90% nursing staff were not aware of time schedule of the vaccine. According to summarized knowledge index only 13.5% nurses had actual knowledge of HPV vaccine. Sixty five percent nurses wanted to vaccinate themselves or to their daughters. Top three aspects of HPV vaccine that nursing staff were most concerned were effectiveness, effect duration and long term effects. Eighty four percent nurses wanted more education and training sessions about cervical cancer prevention and HPV vaccine.Conclusions: Nursing staff in India need to be updated urgently with continuing medical education about cervical cancer prevention and HPV vaccination.
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Background: Cervical cancer continues to be a major health care problem and most common cause of cancer deaths. Many screening methods are available to detect the disease in precancerous stage. Cervical cancer is the only cancer that is preventable with HPV vaccine against the causative agent responsible for this condition. Knowledge and attitude of women determine the likelihood of women undergoing screening procedures and HPV vaccination which will have implications for the future generations. This study was conducted to determine the knowledge, attitude and practice of women towards cervical screening and HPV vaccine.Methods: This is a facility based observational cross-sectional study conducted at Dr. RMLIMS, Lucknow, over a period of 3 months - January 2019 to March 2019. Women attending gynecology OPD were enrolled after verbally consenting for the study and were required to fill a pre-structured questionnaire which was then analyzed and assessed.Results: A total of 368 participants answered the questionnaire. Overall, 154 subjects (41.8%) had adequate knowledge regarding cervical carcinoma risk factors, symptoms, screening for cancer and HPV vaccine. Favorable attitude was seen in 315 (85.5%) participants. Ninety-six participants (26.0%) had ever had a cervical cancer screening and 23 participants (6.2%) had ever received HPV vaccine which was very low. Lack of knowledge and cost factors were the main reasons cited for these low screening and vaccination rates among the participants.Conclusions: The study shows that knowledge was inadequate and screening and vaccination rates were very low in the study population. This highlights the need to educate the community regarding cervical cancer prevention and to make these services readily available at affordable costs to achieve the ultimate goal of elimination of cervical cancer.
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Background: Cervical cancer is still one of the most common cancers affecting females in India, leading to a lot of mortality and morbidity. The objective of this study was to assess the awareness of the human papillomavirus (HPV) infections and vaccination among the medical students of a tertiary care teaching hospital.Methods: A total 300 final year I and II medical students were requested to complete a questionnaire regarding cervical cancer, primary and secondary preventive measures and attitude of students towards HPV vaccination and the answers were then analysed.Results: Among 300 medical students, 46.6% were males and 53.4% were females. Most of them were aware of the common risk factors like early marriage (92.7%), multiple partners (99%), multiparity (83.3%) and HPV exposure (85.7%). Most were aware of the cervical cancer symptoms like offensive vaginal discharge (70%), irregular vaginal bleeding (92.7%) and postcoital bleeding (80.3%). 90% were aware that cervical cancer is preventable and 74% were aware that vaccine is available in India. 70% were aware about the best age to vaccinate is 9-13 years. About 10% were already vaccinated and all were females. Out of 270 students who have not administered HPV vaccine, 53.4% didn’t take the vaccine because of lack of awareness. High cost (18.8%), fear of side effects (13.8%) and doubt on efficacy (14%) were the other reasons reported for non-administration of vaccines.Conclusions: The study showed that there were gaps in knowledge regarding HPV infection and vaccination existed amongst the medical students. So, awareness among the students should be created and a more integrated teaching regarding various aspects of HPV infection, cervical cancers and its prevention needs to be introduced in the medical education system.
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Background: Cervical cancer, despite being a preventable disease, its screening and vaccination still remains poor in our country. The aim of our study was to assess the knowledge and awareness regarding cervical cancer, its risk factors, screening and HPV vaccination.Methods: This cross sectional study was carried out among outpatients attending gynaecology OPD in GEM hospital and Research Centre, a tertiary care centre in Tamil Nadu during the period of April 2019 to June 2019. A total of 500 women, aged 16 years and above were analyzed using a structured questionnaire with multiple choices regarding socio demographic profile, knowledge and awareness about the cervical cancer, its risk factors, screening method and HPV vaccination.Results: Only 16.6% knew that cervical cancer is the most common cancer in Indian women. Majority (74.6%) of them were married, of which 36.2% were aware of Pap smear. Of those who were aware, only one third (12.6%) had their Pap smear done. The awareness of HPV vaccination was only 25% and 3.4% of them were vaccinated. 70.2% of the study participants were willing to be vaccinated after knowing about the vaccination.Conclusions: This study serves to highlight that, the majority of women lack knowledge and awareness concerning cervical cancer and its preventive aspects. This is a major hindrance among Indian women to undergo early screening and timely prevention. Hence creating public awareness of cervical cancer and its prevention is still a priority.
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BACKGROUND: Although several traditional treatments have been applied for recalcitrant viral warts, these treatments have rarely resulted in complete recovery. To treat the recalcitrant viral wart, alternative therapies are required. OBJECTIVE: This study aimed to evaluate the efficacy and safety of quadrivalent HPV vaccine for recalcitrant wart treatment. METHODS: From 2012 to 2014, 17 patients who provided informed consent were enrolled. All patients received 3 doses of quadrivalent HPV vaccine at 0, 2, and 6 months, respectively. During clinic visits, doctors checked the grade of improvement, patient satisfaction, and treatment side effects. After completion of the 3 doses, the patients were followed up for 5 months with outpatient visits and telephone inquiries. RESULTS: After the third dose, 58.8% of patients showed complete remission and 41.2% showed no response after 5 months. There were no statistically significant differences in sex, age, disease duration, number, anatomic site, and previous treatment between the complete remission group and the no-response group. An adverse effect (syncope) was observed in one patient. CONCLUSION: Compared with traditional aggressive therapies, quadrivalent HPV vaccine is a simple method and does not usually interfere with the patient's work or social life. Quadrivalent HPV vaccine is an effective and safe alternative treatment for recalcitrant warts.
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Humans , Ambulatory Care , Clinical Study , Complementary Therapies , Informed Consent , Methods , Outpatients , Papillomaviridae , Patient Satisfaction , Telephone , WartsABSTRACT
Head and neck squamous cell carcinoma (HNSCC) have a broad and varying rate of incidence and mortality around the world. Tobacco smoking and chewing, alcohol consumption are the main etiological agents for HNSCC and have been estimated to account for the majority of disease burden worldwide. Over the past 20 years, there has been an increasing awareness about the human papilloma virus (HPV), the necessary cause of cancer of the cervix that has been etiologically linked with oropharyngeal cancer. Often diagnosed at a late stage this subset of squamous cell carcinoma of the head and neck has an affi nity for the oropharynx and tends to show low diff erentiation histopathologically and better prognosis regardless of the treatment strategy. Th e HPV belongs to the papillomavaviridiae group of virus which can infect the mucosal and cutaneous epithelia in a species-specifi c manner inducing cellular proliferation. Th e HPV can cause active subclinical infection without clinical signs or can also cause clinical infection that can lead to benign, potentially malignant or malignant lesions. Hence, this overview attempts to focus on the relevant characteristics of HPV and its role in oropharyngeal cancer.