ABSTRACT
Objective To investigate dilatancy effect of the Hypertonic Sodium Chloride Hydroxythyl Starch 40 injection (HSH) for the treatment of hemorrhagic shock.Methods 70 cases with trauma induced hemorrhagic shock were randomly divided into two groups:Hypertonic Sodium Chloride Hydroxythyl Starch 40 injection group (H group), Ringer's group (R group), 35 cases in each group.Patients of H group were infused HSH10ml/kg within 30 minutes, the R group were infused Ringer's 10ml/kg at the same time.Central venous pressure (CVP), systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR) and oxygen saturation (SpO2) were monitored before the infusion, after the infusion and finished 30 minutes separately.Na+、Cl-、K+ were examined before infusion and after infusion respectively.Results The CVP、SBP、DBP、HR and SpO2 in both groups were improved than before infusion, but those in H group is much better than R group, with statistical significance (p<0.05).The potassium was reduced moderately and sodium ions and chloride ions were increased in H group than in R group, but it was still within normal range.Conclusion Appling HSH (10ml/kg) to patients with hemorrhagic shock can be better than the compound prescription of sodium lactate.